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anti-Human FLT1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended FLT1 Antibody (supplied by: Log in to see )

Antigen
Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) Antibodies
  • AI323757
  • FLT
  • FLT-1
  • Flt-1
  • FLT1
  • flt1b
  • sFlt1
  • VEGFR-1
  • VEGFR1
Epitope
AA 1160-1210
32
20
12
11
9
9
8
5
5
5
5
5
5
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
245
74
63
12
4
2
2
2
2
2
2
1
1
1
1
1
1
1
Host
Rabbit
188
86
7
4
1
1
Clonality
Polyclonal
Conjugate
This FLT1 antibody is un-conjugated
15
10
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
171
132
55
48
36
25
21
16
12
11
10
5
2
2
1
1
1
1
Supplier
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Catalog No. ABIN725795
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008812695 ABIN919610 IF (p) Alexa Fluor 488 Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.0008812695 ABIN919611 IF (p) Alexa Fluor 555 Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.0008812695 ABIN919613 IF (p) Alexa Fluor 350 Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.0008812695 ABIN919614 IF (p) Alexa Fluor 647 Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.0008812695 ABIN725800 IF (p) Cy5.5 Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.0008812695 ABIN725798 IF (p) Cy3 Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.0008812695 ABIN725801 IF (p) Cy7 Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.0008812695 ABIN725799 IF (p) Cy5 Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.0008812695 ABIN725802 IF (p) FITC Rabbit IgG AA 1160-1210 Log in to see Polyclonal
0.0008812695 ABIN2807478 IF (p) Alexa Fluor 594 Rabbit IgG AA 1160-1210 Log in to see Polyclonal

Top referenced anti-FLT1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-FLT1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 27 Antibodies 29 Antibodies
Flow Cytometry (FACS) 1 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 4 Antibodies 4 Antibodies
Immunofluorescence (IF) 4 Antibodies 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 21 Antibodies 22 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies 12 Antibodies
Immunoprecipitation (IP) 2 Antibodies 10 Antibodies
Western Blotting (WB) 31 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies

General

Antigen Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) Antibodies
Epitope AA 1160-1210
(32), (20), (12), (11), (9), (9), (8), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(245), (74), (63), (12), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(188), (86), (7), (4), (1), (1)
Clonality
Polyclonal
Conjugate This FLT1 antibody is un-conjugated
(15), (10), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(171), (132), (55), (48), (36), (25), (21), (16), (12), (11), (10), (5), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-FLT1 Antibody

Target Details FLT1 Application Details Handling References for anti-FLT1 Antibody (ABIN725795) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from rat VEGFR1
Isotype IgG

Target Details FLT1

Product Details anti-FLT1 Antibody Application Details Handling References for anti-FLT1 Antibody (ABIN725795) Images back to top
Antigen
Alternative Name VEGFR1 (FLT1 Antibody Abstract)
Background

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, and proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts. Has very high affinity for VEGFA and relatively low protein kinase activity, may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR. Modulates KDR signaling by forming heterodimers with KDR. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leading to the activation of phosphatidylinositol kinase and the downstream signaling pathway. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Phosphorylates SRC, YES1 and PLCG, and may also phosphorylate CBL. Promotes phosphorylation of AKT1 and PTK2/FAK1 (By similarity).

Subcellular location: Cytoplasm


Synonyms: VEGFR-1, Vascular endothelial growth factor receptor 1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase receptor FLT, Flt1, Vegfr1
Gene ID 54251
UniProt P53767
Pathways RTK Signaling

Application Details

Product Details anti-FLT1 Antibody Target Details FLT1 Handling References for anti-FLT1 Antibody (ABIN725795) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-FLT1 Antibody Target Details FLT1 Application Details References for anti-FLT1 Antibody (ABIN725795) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-FLT1 Antibody (ABIN725795)

Product Details anti-FLT1 Antibody Target Details FLT1 Application Details Handling Images back to top
Product cited in:

Cheng, Xiang, Yang, Ma, Zhao: "Direct Effects of Bevacizumab on Rat Conjunctival Fibroblast." in: Cell biochemistry and biophysics, 2015

Liu, Wang, Wang, Wang, Xue: "Paeoniflorin attenuates Aβ1-42-induced inflammation and chemotaxis of microglia in vitro and inhibits NF-κB- and VEGF/Flt-1 signaling pathways." in: Brain research, Vol. 1618, pp. 149-58, 2015

Images

Product Details anti-FLT1 Antibody Target Details FLT1 Application Details Handling References for anti-FLT1 Antibody (ABIN725795) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 1160-1210) (ABIN725795) Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-VEGFR1/FLT1 P...
SDS-PAGE (SDS) image for anti-FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 1160-1210) (ABIN725795) Rat lung lysates 30ug, probed (ABIN725795) at 1:200 overnight in 4 °C. Followed by co...
Immunofluorescence (IF) image for anti-FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 1160-1210) (ABIN725795) Image kindly submitted by Victor Blanco as part of the Free Sample Program. Frozen mo...