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anti-Rat (Rattus) FLT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FLT1 Antibody (supplied by: Log in to see )

Antigen
Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) Antibodies
  • FLT1
  • VEGFR1
  • AI323757
  • Flt-1
  • VEGFR-1
  • sFlt1
  • FLT
  • FLT-1
  • flt1b
  • fms-related tyrosine kinase 1
  • vascular endothelial growth factor receptor 1
  • FMS-like tyrosine kinase 1
  • FMS-related tyrosine kinase 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • vascular endothelial growth factor receptor-1
  • FLT1
  • CpipJ_CPIJ012087
  • Flt1
  • flt1
  • FLT-1
Epitope
AA 1160-1210
52
24
19
16
14
14
13
11
9
8
5
5
5
5
5
5
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
378
110
66
16
13
5
3
2
2
2
2
1
1
1
1
1
1
1
Host
Rabbit
206
204
31
7
4
1
Clonality
Polyclonal
Conjugate
This FLT1 antibody is un-conjugated
25
13
10
10
9
9
8
7
7
7
7
6
6
6
6
5
4
3
3
3
3
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
268
221
97
62
55
54
50
40
13
12
12
6
5
3
2
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN725795
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN115391 IHC (p) WB Rabbit C-Term Log in to see Polyclonal 2
1 ABIN115390 IHC (p) WB Rabbit C-Term Log in to see Polyclonal 2
1 ABIN373445 IHC (p) Rabbit C-Term Log in to see Polyclonal 1
1 ABIN568000 IHC (p) WB Rabbit pTyr1333 Log in to see Polyclonal
1 ABIN725804 IHC (p) WB HRP Rabbit IgG AA 1160-1210 Log in to see Polyclonal
1 ABIN725797 IHC (p) WB Biotin Rabbit IgG AA 1160-1210 Log in to see Polyclonal

Top referenced anti-FLT1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-FLT1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 25 Antibodies 41 Antibodies
Immunocytochemistry (ICC) 4 Antibodies 17 Antibodies
Immunofluorescence (IF) 2 Antibodies 19 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies 13 Antibodies
Immunohistochemistry (IHC) 23 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 32 Antibodies
Blocking Peptide (BP) 2 Antibodies
Blocking Reagent (BR) 1 Antibodies
ELISA (Capture) 1 Antibodies
ELISA (Detection) 1 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 13 Antibodies

General

Antigen Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) Antibodies
Epitope AA 1160-1210
(52), (24), (19), (16), (14), (14), (13), (11), (9), (8), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(378), (110), (66), (16), (13), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(206), (204), (31), (7), (4), (1)
Clonality
Polyclonal
Conjugate This FLT1 antibody is un-conjugated
(25), (13), (10), (10), (9), (9), (8), (7), (7), (7), (7), (6), (6), (6), (6), (5), (4), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(268), (221), (97), (62), (55), (54), (50), (40), (13), (12), (12), (6), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-FLT1 Antibody

Target Details FLT1 Application Details Handling References for anti-FLT1 Antibody (ABIN725795) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from rat VEGFR1
Isotype IgG

Target Details FLT1

Product Details anti-FLT1 Antibody Application Details Handling References for anti-FLT1 Antibody (ABIN725795) Images back to top
Antigen
Alternative Name VEGFR1 (FLT1 Antibody Abstract)
Background

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, and proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts. Has very high affinity for VEGFA and relatively low protein kinase activity, may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR. Modulates KDR signaling by forming heterodimers with KDR. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leading to the activation of phosphatidylinositol kinase and the downstream signaling pathway. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Phosphorylates SRC, YES1 and PLCG, and may also phosphorylate CBL. Promotes phosphorylation of AKT1 and PTK2/FAK1 (By similarity).

Subcellular location: Cytoplasm


Synonyms: VEGFR-1, Vascular endothelial growth factor receptor 1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase receptor FLT, Flt1, Vegfr1
Gene ID 54251
UniProt P53767
Pathways RTK Signaling

Application Details

Product Details anti-FLT1 Antibody Target Details FLT1 Handling References for anti-FLT1 Antibody (ABIN725795) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-FLT1 Antibody Target Details FLT1 Application Details References for anti-FLT1 Antibody (ABIN725795) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-FLT1 Antibody (ABIN725795)

Product Details anti-FLT1 Antibody Target Details FLT1 Application Details Handling Images back to top
Product cited in:

Cheng, Xiang, Yang, Ma, Zhao: "Direct Effects of Bevacizumab on Rat Conjunctival Fibroblast." in: Cell biochemistry and biophysics, 2015

Liu, Wang, Wang, Wang, Xue: "Paeoniflorin attenuates A?1-42-induced inflammation and chemotaxis of microglia in vitro and inhibits NF-?B- and VEGF/Flt-1 signaling pathways." in: Brain research, Vol. 1618, pp. 149-58, 2015

Images

Product Details anti-FLT1 Antibody Target Details FLT1 Application Details Handling References for anti-FLT1 Antibody (ABIN725795) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 1160-1210) (ABIN725795) Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-VEGFR1/FLT1 P...
SDS-PAGE (SDS) image for anti-FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 1160-1210) (ABIN725795) Rat lung lysates 30ug, probed (ABIN725795) at 1:200 overnight in 4 °C. Followed by co...
Immunofluorescence (IF) image for anti-FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 1160-1210) (ABIN725795) Image kindly submitted by Victor Blanco as part of the Free Sample Program. Frozen mo...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 1160-1210) (ABIN725795) Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-VEGFR1/FLT1 P...
Western Blotting (WB) image for anti-FLT1 antibody (Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor)) (AA 1160-1210) (ABIN725795) Rat lung lysates 30ug, probed at 1:200 overnight in 4˚C. Followed by conjugation to ...