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Browse our anti-FLT4 (FLT4) Antibodies

Full name:
anti-Fms-Related Tyrosine Kinase 4 Antibodies (FLT4)
On www.antibodies-online.com are 244 Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies from 36 different suppliers available. Additionally we are shipping FLT4 Kits (46) and FLT4 Proteins (32) and many more products for this protein. A total of 330 FLT4 products are currently listed.
Synonyms:
6130401C07, AI323512, cb1059, Chy, Flk-1, Flk1, Flt-4, FLT41, Krd-1, LMPH1A, Ly73, PCL, sVEGFR-2, VEGFR-2, VEGFR-3, VEGFR2, Vegfr3

Most Popular Reactivities for anti-FLT4 (FLT4) Antibodies

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anti-Mouse (Murine) FLT4 Antibodies:

anti-Human FLT4 Antibodies:

anti-Rat (Rattus) FLT4 Antibodies:

All available anti-FLT4 Antibodies

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Top referenced anti-FLT4 Antibodies

  1. Human Monoclonal FLT4 Primary Antibody for FACS - ABIN4896919 : Shawber, Funahashi, Francisco, Vorontchikhina, Kitamura, Stowell, Borisenko, Feirt, Podgrabinska, Shiraishi, Chawengsaksophak, Rossant, Accili, Skobe, Kitajewski: Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. in The Journal of clinical investigation 2007 (PubMed)
    Show all 5 references for ABIN4896919

  2. Human Monoclonal FLT4 Primary Antibody for FACS - ABIN4896918 : Roorda, Ter Elst, Scherpen, Meeuwsen-de Boer, Kamps, de Bont: VEGF-A promotes lymphoma tumour growth by activation of STAT proteins and inhibition of p27(KIP1) via paracrine mechanisms. in European journal of cancer (Oxford, England : 1990) 2010 (PubMed)
    Show all 5 references for ABIN4896918

  3. Human Monoclonal FLT4 Primary Antibody for ELISA, WB - ABIN969147 : Goodyear, Kheyfets, Garcia, Stearns: Role of the VEGFR3/VEGFD receptor axis in TGFbeta1 activation of primary prostate cell lines. in The Prostate 2009 (PubMed)
    Show all 3 references for ABIN969147

  4. Human Polyclonal FLT4 Primary Antibody for WB - ABIN616061 : Paone, Galli, Gabellini, Lukashev, Starace, Gorlach, De Cesaris, Ziparo, Del Bufalo, Sitkovsky, Filippini, Riccioli: Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha. in Neoplasia (New York, N.Y.) 2010 (PubMed)
    Show all 3 references for ABIN616061

  5. Human Polyclonal FLT4 Primary Antibody for IHC (fro), IHC (p) - ABIN115449 : Earnshaw, Halligan, Cooke, Heck, Liu: Topoisomerase II is a structural component of mitotic chromosome scaffolds. in The Journal of cell biology 1985 (PubMed)
    Show all 2 references for ABIN115449

  6. Human Monoclonal FLT4 Primary Antibody for EIA, IHC (fro) - ABIN115161 : Davids, Davids, Charlton, Ng, Chong, Laubscher, Dar, Hodge, Soong, Goh: Response to a novel multitargeted tyrosine kinase inhibitor pazopanib in metastatic Merkel cell carcinoma. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 (PubMed)
    Show all 2 references for ABIN115161

  7. Human Monoclonal FLT4 Primary Antibody for EIA, WB - ABIN115160 : Jussila, Valtola, Partanen, Salven, Heikkilä, Matikainen, Renkonen, Kaipainen, Detmar, Tschachler, Alitalo, Alitalo: Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3. in Cancer research 1998 (PubMed)
    Show all 2 references for ABIN115160

  8. Human Polyclonal FLT4 Primary Antibody for IHC (p) - ABIN115450 : Dietrich, Onderka, Bock, Kruse, Vossmeyer, Stragies, Zahn, Cursiefen: Inhibition of inflammatory lymphangiogenesis by integrin alpha5 blockade. in The American journal of pathology 2007 (PubMed)

  9. Mouse (Murine) Polyclonal FLT4 Primary Antibody for FACS - ABIN4896915 : Imoukhuede, Popel: Expression of VEGF receptors on endothelial cells in mouse skeletal muscle. in PLoS ONE 2012 (PubMed)

More Antibodies against FLT4 Interaction Partners

Mouse (Murine) Fms-Related Tyrosine Kinase 4 (FLT4) interaction partners

  1. Intronic Flk1 (show KDR Antibodies) genetic enhancer element directs arterial-specific expression via RBPJ (show RBPJ Antibodies)-mediated venous repression.

  2. Endothelial SCUBE2 may be a novel coreceptor for VEGFR2 and potentiate VEGF-induced signaling in adult angiogenesis.

  3. VEGFR2 (show KDR Antibodies) signaling is necessary to maintain the integrity of the intestinal mucosal microvasculature during the postnatal period and lack of VEGFR2 (show KDR Antibodies) signaling predisposes to NEC in neonatal mice.

  4. First-in-class selective PET tracers for imaging VEGFR-1 (show FLT1 Antibodies) and VEGFR-2 (show KDR Antibodies) were constructed and successfully validated in an orthotopic murine tumor model.

  5. Blockade of FLT4 suppresses metastasis of melanoma cells by impaired lymphatic vessels.

  6. Vegf-d (show Figf Antibodies) and its receptor Vegfr-3 were more highly expressed in lungs of hyperoxic, versus normoxic, wild-type mice, indicating that components of the Vegf-d (show Figf Antibodies) signalling pathway are up-regulated in hyperoxia.

  7. data for the first time demonstrate a calpain/PTP1B/VEGFR2 negative feedback loop in the regulation of VEGF-induced angiogenesis. Modulation of local PTP1B and/or calpain activities may prove beneficial in the treatment of impaired wound healing in diabetes.

  8. We found that bevacizumab reduced airway hyper-responsiveness (AHR (show AHR Antibodies)) and airway inflammation induced by HDM (show HDAC3 Antibodies). In addition, HDM (show HDAC3 Antibodies) exposure promoted expression of VEGF (show VEGFA Antibodies), and caused AHR (show AHR Antibodies), disruptions of the epithelial barrier, and airway inflammation. Bevacizumab ameliorated AHR (show AHR Antibodies) and the release of Th2 cytokines, thereby protecting the epithelial barrier. Our data suggest that bevacizumab may be a new therapeutic strategy for asthm

  9. Introduction of sVEGFR-2 suppressed lymphangiogenesis in primary lung cancer and also suppressed lymphogenic metastasis by inhibiting VEGF-C (show VEGFC Antibodies), followed by down-regulation of VEGFR-2 (show KDR Antibodies), VEGFR-3 and MMPs.

  10. VEGFB (show VEGFB Antibodies)-Induced Vascular Remodeling in Adipose Tissue Requires VEGF (show VEGFA Antibodies)/VEGFR2 (show KDR Antibodies). VEGFB (show VEGFB Antibodies)-Induced Vascular Remodeling Improves Insulin (show INS Antibodies) Supply, Signaling, and Function in Obese Mice.

Human Fms-Related Tyrosine Kinase 4 (FLT4) interaction partners

  1. These results indicate that VEGF-C (show VEGFC Antibodies)-induced MSC (show MSC Antibodies) osteogenesis is mediated through VEGFR2 (show KDR Antibodies) and VEGFR3, and followed the activation of the ERK (show EPHB2 Antibodies)/RUNX2 (show RUNX2 Antibodies) signaling pathway.

  2. Assessment of VEGFR-2/VEGFR (show KDR Antibodies)-3 on tumor samples might serve as a putative prognostic factor in renal cell carcinoma (show MOK Antibodies) cases, identifying a subset of patients that may benefit from antiangiogenic treatments targeting VEGFR (show KDR Antibodies) receptors.

  3. This study suggests that NRP1 (show NELL1 Antibodies) expression and LVD are independent factors that are likely to predict the risk of LN metastasis in squamous cell carcinoma (SCC (show CYP11A1 Antibodies))of the tongue, whereas the expression of VEGFC (show VEGFC Antibodies), VEGFR3, CCR7 (show CCR7 Antibodies), and SEMA3E (show SEMA3E Antibodies) are nonindependent predictive factors

  4. Data indicate that vascular endothelial growth factor D (VEGF-D (show Figf Antibodies)) was the best indicator of metastasis and vascular endothelial growth factors and receptor-3 (VEGFR-3) may help to determine the prognosis and management of colorectal cancer (CRC (show CALR Antibodies)).

  5. The summarizes the structure and function features of pathway-related molecules of VEGFC (show VEGFC Antibodies)/D-VEGFR3/NRP2 (show NELL2 Antibodies) axis, stages of various tumors and their molecular mechanisms and significances in tuthe expression changes of these molecules in different anatomic organs or histopathologic types or development lymphatic metastasis.

  6. The most extensively accepted signaling pathways promoting lymphangiogenesis in tumors include the secreted lymphangiogenic proteins: VEGF-C (show VEGFC Antibodies) and VEGF-D (show Figf Antibodies), and their cognate receptor on lymphatic endothelium VEGF receptor (show FLT1 Antibodies)-3 (VEGFR-3).

  7. MTA1 (show MTA1 Antibodies) is up-regulated in CRC (show CALR Antibodies); its expression is inversely associated with lymphatic metastases and the expression of VEGFC (show VEGFC Antibodies), VEGFD (show Figf Antibodies) and VEGFR3

  8. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8 (show LGALS8 Antibodies)-dependent crosstalk among VEGF-C (show VEGFC Antibodies), podoplanin (show PDPN Antibodies) and integrin pathways plays a key role.

  9. Report FLT4 genetic alterations in angiosarcomas.

  10. High expression levels of VEGFR1 (show FLT1 Antibodies) and VEGFR3 were associated with a higher rate of lung metastasis.

Zebrafish Fms-Related Tyrosine Kinase 4 (FLT4) interaction partners

  1. miR (show MYLIP Antibodies)-126a directs lymphatic endothelial cell sprouting and extension by interacting with Cxcl12a-mediated chemokine (show CCL1 Antibodies) signaling and Vegfc (show VEGFC Antibodies)-Flt4 signal axis.

  2. Ca(2 (show CA2 Antibodies)+) oscillations depended upon VEGF receptor-2 (Vegfr2) and Vegfr3 in endothelial cells budding from the dorsal aorta (DA) and posterior cardinal (show CARD8 Antibodies) vein, respectively.

  3. Experiments in mice and zebrafish demonstrate that changing levels of VEGFR3/Flt4 modulates aortic lumen diameter consistent with flow-dependent remodeling

  4. In the embryo, phenotypes driven by increased Vegfc (show VEGFC Antibodies) are suppressed in the absence of Ccbe1 (show CCBE1 Antibodies), and Vegfc (show VEGFC Antibodies)-driven sprouting is enhanced by local Ccbe1 (show CCBE1 Antibodies) overexpression. Moreover, Vegfc (show VEGFC Antibodies)- and Vegfr3-dependent Erk (show MAPK1 Antibodies) signaling is impaired in the absence of Ccbe1 (show CCBE1 Antibodies).

  5. Flt4 plays an essential role in lymphangiogenesis [review]

  6. The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc (show VEGFC Antibodies)/Vegfr3 signaling in zebrafish.

  7. Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.

  8. flt4 signalling is suppressed by Dll4 (show DLL4 Antibodies) in developing zebrafish intersegmental arteries.

FLT4 Antigen Profile

Antigen Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.

Alternative names and synonyms associated with FLT4

  • FMS-like tyrosine kinase 4 (Flt4) antibody
  • fms-related tyrosine kinase 4 (FLT4) antibody
  • fms-related tyrosine kinase 4 (Flt4) antibody
  • fms-related tyrosine kinase 4 (flt4) antibody
  • kinase insert domain protein receptor (Kdr) antibody
  • 6130401C07 antibody
  • AI323512 antibody
  • cb1059 antibody
  • Chy antibody
  • Flk-1 antibody
  • Flk1 antibody
  • Flt-4 antibody
  • FLT41 antibody
  • Krd-1 antibody
  • LMPH1A antibody
  • Ly73 antibody
  • PCL antibody
  • sVEGFR-2 antibody
  • VEGFR-2 antibody
  • VEGFR-3 antibody
  • VEGFR2 antibody
  • Vegfr3 antibody

Protein level used designations for FLT4

chylous ascites , receptor protein tyrosine kinase , tyrosine-protein kinase receptor FLT4 , vascular endothelial growth factor receptor 3 , vascular endothelial growth factor receptor-3 , FLT-4 , VEGFR-3 , fms-like tyrosine kinase 4 , soluble VEGFR3 variant 1 , soluble VEGFR3 variant 2 , soluble VEGFR3 variant 3 , FMS-like tyrosine kinase 4 , tyrosine kinase VEGFR-3 , VEGFR3 , expando , receptor tyrosine kinase Flt4 , VEGF receptor-2 , fetal liver kinase 1 , kinase NYK , protein-tyrosine kinase receptor flk-1 , soluble vascular endothelial growth factor receptor 2 , vascular endothelial growth factor receptor 2 , vascular endothelial growth factor receptor- 2 , vascular endothelial growth factor receptor-2

GENE ID SPECIES
14257 Mus musculus
2324 Homo sapiens
114110 Rattus norvegicus
338031 Bos taurus
100008829 Oryctolagus cuniculus
395742 Gallus gallus
30121 Danio rerio
16542 Mus musculus
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