Browse our anti-FLT4 (FLT4) Antibodies

Full name:
anti-Fms-Related Tyrosine Kinase 4 Antibodies (FLT4)
On www.antibodies-online.com are 245 Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies from 36 different suppliers available. Additionally we are shipping FLT4 Kits (46) and FLT4 Proteins (34) and many more products for this protein. A total of 333 FLT4 products are currently listed.
Synonyms:
6130401C07, AI323512, cb1059, Chy, Flk-1, Flk1, Flt-4, FLT41, Krd-1, LMPH1A, Ly73, PCL, sVEGFR-2, VEGFR-2, VEGFR-3, VEGFR2, Vegfr3

Most Popular Reactivities for anti-FLT4 (FLT4) Antibodies

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anti-Mouse (Murine) FLT4 Antibodies:

anti-Human FLT4 Antibodies:

anti-Rat (Rattus) FLT4 Antibodies:

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Top referenced anti-FLT4 Antibodies

  1. Human Monoclonal FLT4 Primary Antibody for FACS - ABIN4896919 : Shawber, Funahashi, Francisco, Vorontchikhina, Kitamura, Stowell, Borisenko, Feirt, Podgrabinska, Shiraishi, Chawengsaksophak, Rossant, Accili, Skobe, Kitajewski: Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. in The Journal of clinical investigation 2007 (PubMed)
    Show all 5 references for 4896919

  2. Human Monoclonal FLT4 Primary Antibody for FACS - ABIN4896918 : Roorda, Ter Elst, Scherpen, Meeuwsen-de Boer, Kamps, de Bont: VEGF-A promotes lymphoma tumour growth by activation of STAT proteins and inhibition of p27(KIP1) via paracrine mechanisms. in European journal of cancer (Oxford, England : 1990) 2010 (PubMed)
    Show all 5 references for 4896918

  3. Human Polyclonal FLT4 Primary Antibody for WB - ABIN616061 : Paone, Galli, Gabellini, Lukashev, Starace, Gorlach, De Cesaris, Ziparo, Del Bufalo, Sitkovsky, Filippini, Riccioli: Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxia-inducible factor 1 alpha. in Neoplasia (New York, N.Y.) 2010 (PubMed)
    Show all 3 references for 616061

  4. Human Polyclonal FLT4 Primary Antibody for ELISA, WB - ABIN1997515 : Shushanov, Bronstein, Adélaïde, Jussila, Tchipysheva, Jacquemier, Stavrovskaya, Birnbaum, Karamysheva: VEGFc and VEGFR3 expression in human thyroid pathologies. in International journal of cancer. Journal international du cancer 2000 (PubMed)
    Show all 2 references for 1997515

  5. Human Monoclonal FLT4 Primary Antibody for EIA, WB - ABIN115160 : Davids, Davids, Charlton, Ng, Chong, Laubscher, Dar, Hodge, Soong, Goh: Response to a novel multitargeted tyrosine kinase inhibitor pazopanib in metastatic Merkel cell carcinoma. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009 (PubMed)
    Show all 2 references for 115160

  6. Human Monoclonal FLT4 Primary Antibody for EIA, IHC (fro) - ABIN115161 : Jussila, Valtola, Partanen, Salven, Heikkilä, Matikainen, Renkonen, Kaipainen, Detmar, Tschachler, Alitalo, Alitalo: Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3. in Cancer research 1998 (PubMed)
    Show all 2 references for 115161

  7. Human Polyclonal FLT4 Primary Antibody for IHC (fro), IHC (p) - ABIN115449 : Earnshaw, Halligan, Cooke, Heck, Liu: Topoisomerase II is a structural component of mitotic chromosome scaffolds. in The Journal of cell biology 1985 (PubMed)
    Show all 2 references for 115449

  8. Mouse (Murine) Polyclonal FLT4 Primary Antibody for FACS - ABIN4896915 : Imoukhuede, Popel: Expression of VEGF receptors on endothelial cells in mouse skeletal muscle. in PLoS ONE 2012 (PubMed)

  9. Human Polyclonal FLT4 Primary Antibody for IHC (p) - ABIN115450 : Dietrich, Onderka, Bock, Kruse, Vossmeyer, Stragies, Zahn, Cursiefen: Inhibition of inflammatory lymphangiogenesis by integrin alpha5 blockade. in The American journal of pathology 2007 (PubMed)

More Antibodies against FLT4 Interaction Partners

Mouse (Murine) Fms-Related Tyrosine Kinase 4 (FLT4) interaction partners

  1. The elevated soluble VEGFR-2 (show KDR Antibodies) that was found in the aortas of apoE (show APOE Antibodies)(-/-) mice with atherosclerosis binds to and diminishes the activity of VEGF-C (show VEGFC Antibodies).

  2. Data show that Leishmania major infection initiates enhanced vascular endothelial growth factor-A (show VEGFA Antibodies)/VEGFR-2 (show KDR Antibodies) signaling and suggest that VEGFR-2 (show KDR Antibodies)-dependent lymphangiogenesis is a mechanism that restricts tissue inflammation in leishmaniasis.

  3. VEGFR3 limits VEGFR2 (show KDR Antibodies) expression and VEGF (show VEGFA Antibodies)/VEGFR2 (show KDR Antibodies) pathway activity in quiescent and angiogenic blood vascular endothelial cells, thereby preventing excessive vascular permeability.

  4. fetal mouse lung mesenchymal cells express Vegfr2 (show KDR Antibodies) and respond to VEGF-A (show VEGFA Antibodies) stimulation.

  5. Deletion of microRNA miR (show MLXIP Antibodies)-150 increased the retinal pathological angiogenesis in high-fat-diet (HFD) induced type 2 diabetic mice, which was in part through vascular endothelial growth factor receptor 2 (VEGFR2 (show KDR Antibodies)).

  6. findings demonstrated that a multi-component Chinese medicine DHI effectively increased blood flow recovery after tissue ischemia in diabetic mice by promoting angiogenesis and improving glucose tolerance through a concomitant activation of VEGF-A (show VEGFA Antibodies)/VEGFR-2 (show KDR Antibodies) and PPARdelta (show PPARD Antibodies) signaling pathways

  7. Intronic Flk1 (show KDR Antibodies) genetic enhancer element directs arterial-specific expression via RBPJ (show RBPJ Antibodies)-mediated venous repression.

  8. Endothelial SCUBE2 may be a novel coreceptor for VEGFR2 and potentiate VEGF-induced signaling in adult angiogenesis.

  9. VEGFR2 (show KDR Antibodies) signaling is necessary to maintain the integrity of the intestinal mucosal microvasculature during the postnatal period and lack of VEGFR2 (show KDR Antibodies) signaling predisposes to NEC in neonatal mice.

  10. First-in-class selective PET tracers for imaging VEGFR-1 (show FLT1 Antibodies) and VEGFR-2 (show KDR Antibodies) were constructed and successfully validated in an orthotopic murine tumor model.

Human Fms-Related Tyrosine Kinase 4 (FLT4) interaction partners

  1. There was a significant decrease in VEGFR3 expression in pulmonary arterial endothelial cells from pulmonary arterial hypertension patients.

  2. By treating LECs with VEGF (show VEGFA Antibodies)-C156S and analyzing subsequent changes in gene expression, we identified several 'immediate early (show JUN Antibodies)' transcription factors that showed a rapid transient upregulation VEGFR-3 stimulation. these results reveal an important and unanticipated role of HOXD10 (show HOXD10 Antibodies) in the regulation of VEGFR-3 signaling in lymphatic endothelial cells, and in the control of lymphangiogenesis and permeability.

  3. The normalized methylation values for the VEGFR1 (show FLT1 Antibodies), VEGFR2 (show KDR Antibodies) and VEGFR3 promoters tended to be higher in the tumour cell lines than in normal tonsil samples, whereas amounts of VEGFR1 (show FLT1 Antibodies), VEGFR2 (show KDR Antibodies) and VEGFR3 messenger RNA were significantly higher

  4. These results indicate that VEGF-C (show VEGFC Antibodies)-induced MSC (show MSC Antibodies) osteogenesis is mediated through VEGFR2 (show KDR Antibodies) and VEGFR3, and followed the activation of the ERK (show EPHB2 Antibodies)/RUNX2 (show RUNX2 Antibodies) signaling pathway.

  5. Assessment of VEGFR-2/VEGFR (show KDR Antibodies)-3 on tumor samples might serve as a putative prognostic factor in renal cell carcinoma (show MOK Antibodies) cases, identifying a subset of patients that may benefit from antiangiogenic treatments targeting VEGFR (show KDR Antibodies) receptors.

  6. This study suggests that NRP1 (show NELL1 Antibodies) expression and LVD are independent factors that are likely to predict the risk of LN metastasis in squamous cell carcinoma (SCC (show CYP11A1 Antibodies))of the tongue, whereas the expression of VEGFC (show VEGFC Antibodies), VEGFR3, CCR7 (show CCR7 Antibodies), and SEMA3E (show SEMA3E Antibodies) are nonindependent predictive factors

  7. Data indicate that vascular endothelial growth factor D (VEGF-D (show Figf Antibodies)) was the best indicator of metastasis and vascular endothelial growth factors and receptor-3 (VEGFR-3) may help to determine the prognosis and management of colorectal cancer (CRC (show CALR Antibodies)).

  8. The summarizes the structure and function features of pathway-related molecules of VEGFC (show VEGFC Antibodies)/D-VEGFR3/NRP2 (show NELL2 Antibodies) axis, stages of various tumors and their molecular mechanisms and significances in tuthe expression changes of these molecules in different anatomic organs or histopathologic types or development lymphatic metastasis.

  9. The most extensively accepted signaling pathways promoting lymphangiogenesis in tumors include the secreted lymphangiogenic proteins: VEGF-C (show VEGFC Antibodies) and VEGF-D (show Figf Antibodies), and their cognate receptor on lymphatic endothelium VEGF receptor (show FLT1 Antibodies)-3 (VEGFR-3).

  10. MTA1 (show MTA1 Antibodies) is up-regulated in CRC (show CALR Antibodies); its expression is inversely associated with lymphatic metastases and the expression of VEGFC (show VEGFC Antibodies), VEGFD (show Figf Antibodies) and VEGFR3

Zebrafish Fms-Related Tyrosine Kinase 4 (FLT4) interaction partners

  1. miR (show MYLIP Antibodies)-126a directs lymphatic endothelial cell sprouting and extension by interacting with Cxcl12a-mediated chemokine (show CCL1 Antibodies) signaling and Vegfc (show VEGFC Antibodies)-Flt4 signal axis.

  2. Ca(2 (show CA2 Antibodies)+) oscillations depended upon VEGF receptor-2 (Vegfr2) and Vegfr3 in endothelial cells budding from the dorsal aorta (DA) and posterior cardinal (show CARD8 Antibodies) vein, respectively.

  3. Experiments in mice and zebrafish demonstrate that changing levels of VEGFR3/Flt4 modulates aortic lumen diameter consistent with flow-dependent remodeling

  4. In the embryo, phenotypes driven by increased Vegfc (show VEGFC Antibodies) are suppressed in the absence of Ccbe1 (show CCBE1 Antibodies), and Vegfc (show VEGFC Antibodies)-driven sprouting is enhanced by local Ccbe1 (show CCBE1 Antibodies) overexpression. Moreover, Vegfc (show VEGFC Antibodies)- and Vegfr3-dependent Erk (show MAPK1 Antibodies) signaling is impaired in the absence of Ccbe1 (show CCBE1 Antibodies).

  5. Flt4 plays an essential role in lymphangiogenesis [review]

  6. The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc (show VEGFC Antibodies)/Vegfr3 signaling in zebrafish.

  7. Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.

  8. flt4 signalling is suppressed by Dll4 (show DLL4 Antibodies) in developing zebrafish intersegmental arteries.

FLT4 Antigen Profile

Antigen Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.

Alternative names and synonyms associated with FLT4

  • FMS-like tyrosine kinase 4 (Flt4) antibody
  • fms-related tyrosine kinase 4 (FLT4) antibody
  • fms-related tyrosine kinase 4 (Flt4) antibody
  • fms-related tyrosine kinase 4 (flt4) antibody
  • kinase insert domain protein receptor (Kdr) antibody
  • 6130401C07 antibody
  • AI323512 antibody
  • cb1059 antibody
  • Chy antibody
  • Flk-1 antibody
  • Flk1 antibody
  • Flt-4 antibody
  • FLT41 antibody
  • Krd-1 antibody
  • LMPH1A antibody
  • Ly73 antibody
  • PCL antibody
  • sVEGFR-2 antibody
  • VEGFR-2 antibody
  • VEGFR-3 antibody
  • VEGFR2 antibody
  • Vegfr3 antibody

Protein level used designations for FLT4

chylous ascites , receptor protein tyrosine kinase , tyrosine-protein kinase receptor FLT4 , vascular endothelial growth factor receptor 3 , vascular endothelial growth factor receptor-3 , FLT-4 , VEGFR-3 , fms-like tyrosine kinase 4 , soluble VEGFR3 variant 1 , soluble VEGFR3 variant 2 , soluble VEGFR3 variant 3 , FMS-like tyrosine kinase 4 , tyrosine kinase VEGFR-3 , VEGFR3 , expando , receptor tyrosine kinase Flt4 , VEGF receptor-2 , fetal liver kinase 1 , kinase NYK , protein-tyrosine kinase receptor flk-1 , soluble vascular endothelial growth factor receptor 2 , vascular endothelial growth factor receptor 2 , vascular endothelial growth factor receptor- 2 , vascular endothelial growth factor receptor-2

GENE ID SPECIES
14257 Mus musculus
2324 Homo sapiens
114110 Rattus norvegicus
338031 Bos taurus
100008829 Oryctolagus cuniculus
395742 Gallus gallus
30121 Danio rerio
16542 Mus musculus
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