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FLT4 antibody

FLT4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4H4 unconjugated
Catalog No. ABIN969147
  • Target See all FLT4 Antibodies
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    Reactivity
    • 73
    • 47
    • 16
    • 12
    Human
    Host
    • 67
    • 21
    • 4
    • 2
    Mouse
    Clonality
    • 68
    • 26
    Monoclonal
    Conjugate
    • 52
    • 8
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLT4 antibody is un-conjugated
    Application
    • 52
    • 39
    • 35
    • 26
    • 14
    • 13
    • 13
    • 8
    • 8
    • 7
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human FLT4 expressed in E. coli.
    Clone
    4H4
    Isotype
    IgG1
    Top Product
    Discover our top product FLT4 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Goodyear, Kheyfets, Garcia, Stearns: "Role of the VEGFR3/VEGFD receptor axis in TGFbeta1 activation of primary prostate cell lines." in: The Prostate, Vol. 69, Issue 9, pp. 982-90, (2009) (PubMed).

    Pan, Chang, Chang, Su, Wang, Hung: "Sumoylation of Prox1 controls its ability to induce VEGFR3 expression and lymphatic phenotypes in endothelial cells." in: Journal of cell science, Vol. 122, Issue Pt 18, pp. 3358-64, (2009) (PubMed).

    Jayasinghe, Simiantonaki, Michel-Schmidt, Kirkpatrick: "Endothelial VEGFR-3 expression in colorectal carcinomas is associated with hematogenous metastasis." in: Oncology reports, Vol. 22, Issue 5, pp. 1093-100, (2009) (PubMed).

  • Target
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    Alternative Name
    FLT4 (FLT4 Products)
    Synonyms
    FLT41 antibody, LMPH1A antibody, PCL antibody, VEGFR3 antibody, AI323512 antibody, Chy antibody, Flt-4 antibody, VEGFR-3 antibody, Vegfr3 antibody, cb1059 antibody, fms related tyrosine kinase 4 antibody, FMS-like tyrosine kinase 4 antibody, fms-related tyrosine kinase 4 antibody, FLT4 antibody, Flt4 antibody, flt4 antibody
    Background

    Description: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. Tissue specificity: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain. VEGFR-3 is induced in all endothelial cells (EC's) during early embryogenesis, and its expression eventually disappears from the vascular endothelial cells of adult tissues. VEGFR-3 is constitutively expressed in the adult lymphatic endothelium. Although VEGFR-3 is not expressed in adult blood vessels, it is induced in vascular endothelial cells of tumor-bearing tissues.VEGFR-3 expression in adults is largely restricted to the endothelial cells of the lymphatic system, and high endothelial venules (HEV).

    Aliases: PCL, FLT41, LMPH1A, VEGFR3, FLT4

    Molecular Weight
    145 kDa
    Gene ID
    2324
    HGNC
    2324
    Pathways
    RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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