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anti-Mouse (Murine) FLT4 antibody for Functional Studies

Recommended FLT4 Antibody (supplied by: Log in to see )

Antigen
Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies
  • 6130401C07
  • AI323512
  • cb1059
  • Chy
  • Flk-1
  • Flk1
  • Flt-4
  • FLT41
  • Krd-1
  • LMPH1A
  • Ly73
  • PCL
  • sVEGFR-2
  • VEGFR-2
  • VEGFR-3
  • VEGFR2
  • Vegfr3
  • VEGFR3
Reactivity
Mouse (Murine)
159
75
31
2
1
Host
Rat
120
61
16
4
1
Clonality
Monoclonal
Conjugate
This FLT4 antibody is un-conjugated
13
7
6
6
4
2
2
2
2
2
2
2
2
2
2
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
113
83
55
31
26
22
19
11
10
9
4
3
2
2
1
Supplier
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Catalog No. ABIN281068
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008715322 ABIN2154588 Func FACS Rat IgG2a kappa Log in to see AFL4
0.0008715322 ABIN282491 Func FACS Rat IgG2a Log in to see AFL4

Similar anti-FLT4 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 19 Antibodies
Flow Cytometry (FACS) 17 Antibodies
Functional Studies (Func) 3 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 14 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 16 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Western Blotting (WB) 34 Antibodies

General

Antigen Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies
Reactivity Mouse (Murine)
(159), (75), (31), (2), (1)
Host Rat
(120), (61), (16), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FLT4 antibody is un-conjugated
(13), (7), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(113), (83), (55), (31), (26), (22), (19), (11), (10), (9), (4), (3), (2), (2), (1)
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Product Details anti-FLT4 Antibody

Target Details FLT4 Application Details Handling Images
Specificity The AFL4 monoclonal antibody reacts with the mouse VEGF receptor-3, also known as Flt-4. This 195 kDa molecule was identified as an endothelial-specific member of the receptor tyrosine kinase (RTK) family. During early embryogenesis all endothelial cells express VEGFR-3, while in the adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. However, VEGFR-3 expression is induced in the adult tissue upon tumor implementation suggesting an important role for this receptor in the tumor angiogenesis. VEGF-C and VEGF-D bind to and activate VEGFR-3. AFL4 is an antagonist mAb.
Characteristics The AFL4 monoclonal antibody reacts with the mouse VEGF receptor-3, also known as Flt-4. This 195 kDa molecule was identified as an endothelial-specific member of the receptor tyrosine kinase (RTK) family. During early embryogenesis all endothelial cells express VEGFR-3, while in the adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. However, VEGFR-3 expression is induced in the adult tissue upon tumor implementation suggesting an important role for this receptor in the tumor angiogenesis. VEGF-C and VEGF-D bind to and activate VEGFR-3. AFL4 is an antagonist mAb.
Synonyms: Synonyms: VEGFR3, VEGF R3, VEGF receptor 3, Flt-4, Flt4, vascular endothelial growth factor receptor 3
Purification Affinity Purified
Clone AFL4
Isotype IgG2a kappa

Target Details FLT4

Product Details anti-FLT4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name VEGFR3 (FLT4 Antibody Abstract)
Research Area Cancer, Angiogenesis, Growth Factors, Cell Cycle, Kinases/Phosphatases, Tyrosine Kinases
Pathways RTK Signaling

Application Details

Product Details anti-FLT4 Antibody Target Details FLT4 Handling Images back to top
Application Notes Applications reported: The AFL4 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunoblotting (WB), and immunohistochemical staining of frozen tissue sections. It has also been reported in blocking of ligand binding. (Please use Functional Grade purified AFL4, cat. 16- 5988, in functional assays.)

Applications tested: The AFL4 antibody has been tested by flow cytometric analysis of in vitro differentiated mouse endothelial cells. In brief, mouse ES cells were incubated on collagen IV matrix for 4 days and subsequently stimulated with VEGF under serum free conditions to induce further differentiation. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Restrictions For Research Use only

Handling

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details Images back to top
Concentration 0.5 mg/mL
Buffer aqueous buffer, 0.09 % sodium azide, may contain carrier protein/stabilizer
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Monoclonal antibodies should not be stored at a temperature below -25 °C due to the aggregation effect of the protein.
Storage 4 °C