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anti-Human LTK antibody for Enzyme Immunoassay

Recommended LTK Antibody (supplied by: Log in to see )

Antigen
Leukocyte Receptor tyrosine Kinase (LTK) Antibodies
  • ALK
  • LTK
  • si:dz107o16.1
  • TYK1
Epitope
N-Term
22
19
15
7
6
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
62
25
2
1
Host
Rabbit
79
2
1
Clonality
Polyclonal
Conjugate
This LTK antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
64
40
11
8
5
1
Supplier
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Catalog No. ABIN359893
$ 390.50
Plus shipping costs $45.00

Top referenced anti-LTK antibody for Enzyme Immunoassay

  • Human Polyclonal LTK Primary Antibody for EIA, WB - ABIN359893 (3 Publications): Toyoshima, Kozutsumi, Maru, Hagiwara, Furuya, Mioh, Hanai, Takaku, Yazaki, Hirai: Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein. in Proceedings of the National Academy of Sciences of the United States of America 1993 (PubMed)

Similar anti-LTK Antibodies

Application / Reactivity Human
ELISA 24 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Western Blotting (WB) 51 Antibodies

General

Antigen Leukocyte Receptor tyrosine Kinase (LTK) Antibodies
Epitope N-Term
(22), (19), (15), (7), (6), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(62), (25), (2), (1)
Host Rabbit
(79), (2), (1)
Clonality
Polyclonal
Conjugate This LTK antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(64), (40), (11), (8), (5), (1)
Pubmed 3 references available
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Product Details anti-LTK Antibody

Target Details LTK Application Details Handling References for anti-LTK Antibody (ABIN359893) Images
Specificity This antibody reacts to LTK.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LTK.
Isotype Ig

Target Details LTK

Product Details anti-LTK Antibody Application Details Handling References for anti-LTK Antibody (ABIN359893) Images back to top
Antigen
Alternative Name LTK / TYK1 (LTK Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: Leukocyte tyrosine kinase receptor, Protein tyrosine kinase 1
Gene ID 4058, 9606
UniProt P29376
Pathways RTK Signaling

Application Details

Product Details anti-LTK Antibody Target Details LTK Handling References for anti-LTK Antibody (ABIN359893) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-LTK Antibody Target Details LTK Application Details References for anti-LTK Antibody (ABIN359893) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-LTK Antibody (ABIN359893)

Product Details anti-LTK Antibody Target Details LTK Application Details Handling Images back to top
Background publications

Toyoshima, Kozutsumi, Maru, Hagiwara, Furuya, Mioh, Hanai, Takaku, Yazaki, Hirai: "Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 12, pp. 5404-8, 1993

Krolewski, Dalla-Favera: "The ltk gene encodes a novel receptor-type protein tyrosine kinase." in: The EMBO journal, Vol. 10, Issue 10, pp. 2911-9, 1991

Maru, Hirai, Takaku: "Human ltk: gene structure and preferential expression in human leukemic cells." in: Oncogene research, Vol. 5, Issue 3, pp. 199-204, 1990

Images

Product Details anti-LTK Antibody Target Details LTK Application Details Handling References for anti-LTK Antibody (ABIN359893) back to top
Supplier Images
 image for anti-LTK antibody (Leukocyte Receptor tyrosine Kinase) (N-Term) (ABIN359893) anti-Leukocyte Receptor tyrosine Kinase (LTK) (N-Term) antibody