LTK antibody

Catalog No. ABIN7183757

Product Details anti-LTK Antibody

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human LTK.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LTK

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Alternative Name: LTK (LTK Products)

Synonyms: LTK antibody, ALK antibody, TYK1 antibody, si:dz107o16.1 antibody, leukocyte receptor tyrosine kinase antibody, leukocyte tyrosine kinase antibody, Ltk antibody, LTK antibody, ltk antibody

Background:

Background: Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.

Toyoshima H., Proc. Natl. Acad. Sci. U.S.A. 90:5404-5408(1993).
Krolewski J.J., EMBO J. 10:2911-2919(1991).
Maru Y., Oncogene Res. 5:199-204(1990).

Aliases: Leukocyte receptor tyrosine kinase antibody, Leukocyte tyrosine kinase antibody, Leukocyte tyrosine kinase receptor antibody, Ltk antibody, LTK_HUMAN antibody, Protein tyrosine kinase 1 antibody, TYK 1 antibody, TYK1 antibody

UniProt: P29376

Pathways: RTK Signaling