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anti-Human MME antibody for Complement Mediated Cell Depletion

Recommended MME Antibody (supplied by: Log in to see )

Antigen
Membrane Metallo-Endopeptidase (MME) Antibodies
  • MME
  • NEP
  • CD10
  • CALLA
  • CAK
  • CD167
  • DDR
  • EDDR1
  • HGK2
  • MCK10
  • NTRK4
  • PTK3
  • PTK3A
  • RTK6
  • TRKE
  • AV378681
  • Mmel
  • 6030454K05Rik
  • C85356
  • SFE
  • Nep
  • membrane metallo-endopeptidase
  • discoidin domain receptor tyrosine kinase 1
  • matrix metallopeptidase 12
  • membrane metallo endopeptidase
  • MME
  • DDR1
  • Mmp12
  • Mme
Reactivity
Human
568
87
76
16
14
3
3
2
2
1
1
1
1
1
1
Host
Mouse
396
184
4
3
Clonality
Monoclonal
Conjugate
This MME antibody is conjugated to PE
59
46
33
22
9
8
8
8
7
6
5
5
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Complement Mediated Cell Depletion (CMCD), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
303
268
178
140
105
75
74
46
42
14
13
10
5
4
3
2
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2662920
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2662921 CMCD FACS IP IHC WB PE Mouse IgG1 kappa Log in to see HI10a 5

Top referenced anti-MME antibody for Complement Mediated Cell Depletion

Similar anti-MME Antibodies

Application / Reactivity Human
Complement Mediated Cell Depletion (CMCD) 2 Antibodies
Confocal Microscopy (CM) 14 Antibodies
Cytometry by Time of Flight (CyTOF) 3 Antibodies
ELISA 127 Antibodies
ELISA (Capture) 1 Antibodies
ELISA (Detection) 1 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 304 Antibodies
Functional Studies (Func) 4 Antibodies
Immunoassay (IA) 1 Antibodies
Immunocytochemistry (ICC) 39 Antibodies
Immunofluorescence (IF) 75 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 169 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies

General

Antigen Membrane Metallo-Endopeptidase (MME) Antibodies
Reactivity Human
(568), (87), (76), (16), (14), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(396), (184), (4), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MME antibody is conjugated to PE
(59), (46), (33), (22), (9), (8), (8), (8), (7), (6), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Complement Mediated Cell Depletion (CMCD), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(303), (268), (178), (140), (105), (75), (74), (46), (42), (14), (13), (10), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-MME Antibody

Target Details MME Application Details Handling References for anti-MME Antibody (ABIN2662920) Images
Cross-Reactivity Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Capuchin Monkey
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone HI10a
Isotype IgG1 kappa

Target Details MME

Product Details anti-MME Antibody Application Details Handling References for anti-MME Antibody (ABIN2662920) Images back to top
Antigen
Alternative Name CD10 (MME Antibody Abstract)
Background CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.
Research Area Cancer, Hematopoietic Progenitors, Hematopoietic Stem Cells, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells
Pathways RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones

Application Details

Product Details anti-MME Antibody Target Details MME Handling References for anti-MME Antibody (ABIN2662920) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MME Antibody Target Details MME Application Details References for anti-MME Antibody (ABIN2662920) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-MME Antibody (ABIN2662920)

Product Details anti-MME Antibody Target Details MME Application Details Handling Images back to top
Background publications

Denny, Yalavarthi, Zhao, Thacker, Anderson, Sandy, McCune, Kaplan: "A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 6, pp. 3284-97, 2010

DallEra, True, Siegel, Porter, Sherertz, Liu: "Differential expression of CD10 in prostate cancer and its clinical implication." in: BMC urology, Vol. 7, pp. 3, 2007

Yoshino, Ami, Terao, Tashiro, Honda: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, 2000

Lu, Gerard, Kolakowski, Bozza, Zurakowski, Finco, Carroll, Gerard: "Neutral endopeptidase modulation of septic shock." in: The Journal of experimental medicine, Vol. 181, Issue 6, pp. 2271-5, 1995

Shipp, Look: "Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key!" in: Blood, Vol. 82, Issue 4, pp. 1052-70, 1993

Images

Product Details anti-MME Antibody Target Details MME Application Details Handling References for anti-MME Antibody (ABIN2662920) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-MME antibody (Membrane Metallo-Endopeptidase)  (PE) (ABIN2662920) anti-Membrane Metallo-Endopeptidase (MME) antibody (PE)