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anti-Human MME antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MME Antibody (supplied by: Log in to see )

Antigen
Membrane Metallo-Endopeptidase (MME) Antibodies
  • 6030454K05Rik
  • AV378681
  • C85356
  • CAK
  • CALLA
  • CD10
  • CD167
  • DDR
  • EDDR1
  • HGK2
  • MCK10
  • MME
  • Mmel
  • Nep
  • NEP
  • NTRK4
  • PTK3
  • PTK3A
  • RTK6
  • SFE
  • TRKE
Epitope
C-Term
33
21
19
16
14
12
7
6
6
6
6
6
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
568
65
63
15
15
1
Host
Rabbit
406
177
3
Clonality
Polyclonal
Conjugate
This MME antibody is un-conjugated
61
49
35
24
9
7
7
7
7
5
5
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
294
256
134
132
99
75
67
52
46
14
11
8
4
4
3
2
2
2
1
1
1
Supplier
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Catalog No. ABIN453219
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34288716 ABIN951144 EIA IHC (p) WB Rabbit Ig AA 728-755, Middle Region Log in to see Polyclonal 3
0.34288716 ABIN214166 IHC (fro) IHC (p) ELISA Mouse IgG2b Log in to see
0.34288716 ABIN2649265 IHC (p) Mouse Log in to see
0.0008982679 ABIN1687426 IHC (p) Rabbit IgG Log in to see SP67 2
0.0008982679 ABIN391499 FACS IHC (p) WB Rabbit Ig AA 506-534, C-Term Log in to see Polyclonal 4
0.0008982679 ABIN654151 IHC (p) WB Rabbit Ig AA 721-747, Center Log in to see Polyclonal 2
0.0008982679 ABIN1105718 Func FACS IHC (p) Mouse IgG2a Log in to see B-E3 2
0.0008982679 ABIN1687388 IHC (p) WB Rabbit IgG Log in to see SP67 5
0.0008982679 ABIN114759 IHC (fro) IHC (p) Mouse IgG1 Log in to see 56C6 4
0.0008982679 ABIN669666 IF (p) IHC (p) WB Rabbit IgG AA 500-550 Log in to see Polyclonal 1
0.0008982679 ABIN115280 IHC (fro) IHC (p) Mouse IgG1 Log in to see 56C6 4
0.0008982679 ABIN302259 EIA IHC (fro) IHC (p) Mouse IgG2b Log in to see n-a
0.0008982679 ABIN1105719 IHC (p) Mouse IgG2b Log in to see 2A1H5E1 2
0.0008982679 ABIN1688093 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal
0.0008982679 ABIN1688930 IHC (p) Rabbit IgG N-Term Log in to see SP179
0.0008982679 ABIN1687382 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal
0.0008982679 ABIN1688911 FACS IHC (p) WB Rabbit IgG N-Term Log in to see SP179
0.0008982679 ABIN254462 FACS IHC (p) IHC FITC Mouse IgG1 Log in to see SN5c
0.0008982679 ABIN373155 IHC (p) Rabbit Internal Region Log in to see Polyclonal
0.0008982679 ABIN1105720 FACS IHC (p) Mouse IgG2a Log in to see B-E3

Top referenced anti-MME antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-MME Antibodies

Application / Reactivity Human
Complement Mediated Cell Depletion (CMCD) 2 Antibodies
Confocal Microscopy (CM) 14 Antibodies
ELISA 124 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 302 Antibodies
Functional Studies (Func) 4 Antibodies
Immunoassay (IA) 1 Antibodies
Immunocytochemistry (ICC) 43 Antibodies
Immunofluorescence (IF) 75 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 130 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 8 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 3 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 49 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 100 Antibodies
Immunoprecipitation (IP) 69 Antibodies

General

Antigen Membrane Metallo-Endopeptidase (MME) Antibodies
Epitope C-Term
(33), (21), (19), (16), (14), (12), (7), (6), (6), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(568), (65), (63), (15), (15), (1)
Host Rabbit
(406), (177), (3)
Clonality
Polyclonal
Conjugate This MME antibody is un-conjugated
(61), (49), (35), (24), (9), (7), (7), (7), (7), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(294), (256), (134), (132), (99), (75), (67), (52), (46), (14), (11), (8), (4), (4), (3), (2), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-MME Antibody

Target Details MME Application Details Handling References for anti-MME Antibody (ABIN453219) Images
Specificity This antibody reacts to Neprilysin (CD10).
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human Neprilysin

Target Details MME

Product Details anti-MME Antibody Application Details Handling References for anti-MME Antibody (ABIN453219) Images back to top
Antigen
Alternative Name CD10 / Neprilysin (MME Antibody Abstract)
Background MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11
Gene ID 4311
NCBI Accession NP_000893
UniProt P08473
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling

Application Details

Product Details anti-MME Antibody Target Details MME Handling References for anti-MME Antibody (ABIN453219) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MME Antibody Target Details MME Application Details References for anti-MME Antibody (ABIN453219) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-MME Antibody (ABIN453219)

Product Details anti-MME Antibody Target Details MME Application Details Handling Images back to top
Background publications

Dakka, Bellaoui, Bouzid, Khattab, Bakri, Benjouad: "CD10 AND CD34 expression in childhood acute lymphoblastic leukemia in Morocco: clinical relevance and outcome." in: Pediatric hematology and oncology, Vol. 26, Issue 4, pp. 216-31, 2009

Wang, Wang, Malter, Wang: "Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells." in: Journal of neurochemistry, Vol. 108, Issue 4, pp. 1072-82, 2009

Images

Product Details anti-MME Antibody Target Details MME Application Details Handling References for anti-MME Antibody (ABIN453219) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MME antibody (Membrane Metallo-Endopeptidase) (C-Term) (ABIN453219) Formalin-fixed and paraffin-embedded human kidney carcinoma with Neprilysin Antibody ...
Western Blotting (WB) image for anti-MME antibody (Membrane Metallo-Endopeptidase) (C-Term) (ABIN453219) Western blot analysis of Neprilysin Antibody (C-term) in A2058,A375,Ramos cell line l...