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Browse our anti-PDGFD (PDGFD) Antibodies

Full name:
anti-Platelet Derived Growth Factor D Antibodies (PDGFD)
On are 61 Platelet Derived Growth Factor D (PDGFD) Antibodies from 12 different suppliers available. Additionally we are shipping PDGFD Kits (47) and PDGFD Proteins (10) and many more products for this protein. A total of 125 PDGFD products are currently listed.
1110003I09Rik, IEGF, PDGFD, rSCDGF-B, SCDGF-B, Scdgfb
list all antibodies Gene Name GeneID UniProt
PDGFD 80310 Q9GZP0
PDGFD 66018 Q9EQT1
PDGFD 71785 Q925I7

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Most Popular Reactivities for anti-PDGFD (PDGFD) Antibodies

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anti-Human PDGFD Antibodies:

anti-Rat (Rattus) PDGFD Antibodies:

anti-Mouse (Murine) PDGFD Antibodies:

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Top referenced anti-PDGFD Antibodies

  1. Human Polyclonal PDGFD Primary Antibody for WB - ABIN2787839 : Liu, Changsirikulchai, Hudkins, Banas, Kowalewska, Yang, Wietecha, Volpone, Gilbertson, Alpers: Identification of platelet-derived growth factor D in human chronic allograft nephropathy. in Human pathology 2008 (PubMed)

  2. Human Polyclonal PDGFD Primary Antibody for IP, WB - ABIN529260 : Rizvi, Mertens, Bronk, Hirsova, Dai, Roberts, Kaufmann, Gores: Platelet-derived growth factor primes cancer-associated fibroblasts for apoptosis. in The Journal of biological chemistry 2014 (PubMed)

  3. Human Polyclonal PDGFD Primary Antibody for IF (p), IHC (p) - ABIN714581 : Hurley, Adams, Wang, Jiang, Meo Burt, Du, Xiao: Accelerated Fracture Healing in Transgenic Mice Overexpressing an Anabolic Isoform of Fibroblast Growth Factor 2. in Journal of cellular biochemistry 2015 (PubMed)

More Antibodies against PDGFD Interaction Partners

Human Platelet Derived Growth Factor D (PDGFD) interaction partners

  1. Novel findings reveal a new paradigm in matriptase (show ST14 Antibodies) activation involving PDGF-D-specific signal transduction leading to extracellular acidosis.

  2. PDGF-D expression is associated with miR (show MLXIP Antibodies)-106a and Twist1 (show TWIST1 Antibodies) in HCC (show FAM126A Antibodies) patients

  3. PDGF-D is highly expressed by ASCs, where it acts as a potent mitogenic factor.

  4. PDGFD, CDH1 and SLIT2 are upregulated in low grade meningiomas and schwannomas compared with healthy tissue.

  5. PDGF (show PDGFA Antibodies)-DD secreted by gastric cancer derived mesenchymal stem cells is capable of promoting gastric cancer cell progression in vitro and in vivo.

  6. Data suggest that targeting platelet-derived growth factor-D as a strategy for endometrial cancer treatment.

  7. Compared with matched normal endometrial cases, PDGF-D was up-regulated in endometrial cancer. Expression of PDGF-D protein, found in 78% of the cases, was associated with nonendometrioid histologic type.

  8. PDGFD-PDGFRbeta signalling is required for human neocortical development and local production of growth factors by radial glia supports the expanded germinal region and progenitor heterogeneity of species with large brains

  9. PDGF-D is highly expressed in gemcitabine resistant (GR) liver neoplasm cells. Furthermore, down-regulation of PDGF-D in GR cells led to partial reversal of the EMT (show ITK Antibodies) phenotype.

  10. Down-regulation of platelet-derived growth factor-D expression blockades NF-kappaB (show NFKB1 Antibodies) pathway to inhibit cell proliferation and invasion as well as induce apoptosis in esophageal squamous cell carcinoma.

Mouse (Murine) Platelet Derived Growth Factor D (PDGFD) interaction partners

  1. Inactivation of the Pdgfd gene resulted in a mild phenotype in C57BL/6 mice, and the offspring was viable, fertile and generally in good health.

  2. PDGF-D intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1 (show TIMP1 Antibodies)/MMP-2 (show MMP2 Antibodies)/MMP (show MMP2 Antibodies)-9 (show MMP9 Antibodies) system, and PDGF-D signaling is mediated through both PDGF (show PDGFA Antibodies)-alpha and -beta receptors.

  3. Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex

  4. PDGF D represents a potentially promising target for prostate carcinoma treatment resistance in the absence of PTEN (show PTEN Antibodies) function, and warrants further laboratory evaluation and clinical study.

  5. Data indicate that the proteolytic processing of full-length PDGF-D is required for PDGF-D activation of preosteoclasts, and that beta-PDGFR (show PDGFRB Antibodies) is present in activated osteoclasts.

  6. identified PDGF (show PDGFA Antibodies)-DD as an important target gene for antiangiogenic therapy due to its pleiotropic effects on vascular and non-vascular cells. PDGF (show PDGFA Antibodies)-DD inhibition may offer new therapeutic options to treat neovascular diseases

  7. Failure of laminin alpha4-mediated down-regulation of PDGF (show PDGFA Antibodies) activity contributes to the progressive renal lesions in this animal model.

  8. These results suggest that PDGF-D induce cellular transformation and promote tumour growth by accelerating the proliferation rate of the tumour cells, and by stimulation of tumour neovascularization.

  9. PDGF-D plays an important role in the pathogenesis of tubulointerstitial injury through binding of PDGF (show PDGFA Antibodies)-Rbeta in obstructive ureteral nephropathy

  10. PDGF (show PDGFA Antibodies)-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns.

PDGFD Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.

Alternative names and synonyms associated with PDGFD

  • platelet derived growth factor D (PDGFD) antibody
  • platelet derived growth factor D (Pdgfd) antibody
  • platelet-derived growth factor, D polypeptide (Pdgfd) antibody
  • 1110003I09Rik antibody
  • IEGF antibody
  • PDGFD antibody
  • rSCDGF-B antibody
  • SCDGF-B antibody
  • Scdgfb antibody

Protein level used designations for PDGFD

platelet derived growth factor D , PDGF-D , platelet-derived growth factor D , platelet-derived growth factor D-like , iris-expressed growth factor , spinal cord derived growth factor B , spinal cord-derived growth factor B , spinal cord-derived growth factor-B , SCDGF-B , platelet-derived growth factor, D polypeptide , spinal-cord derived growth factor-B protein

466765 Pan troglodytes
100061488 Equus caballus
100172718 Pongo abelii
100398033 Callithrix jacchus
100586178 Nomascus leucogenys
80310 Homo sapiens
66018 Rattus norvegicus
100008912 Oryctolagus cuniculus
100713757 Cavia porcellus
479460 Canis lupus familiaris
525931 Bos taurus
418978 Gallus gallus
101117784 Ovis aries
71785 Mus musculus
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