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anti-Human Phospholipase C gamma 2 antibody for Enzyme Immunoassay

Recommended Phospholipase C gamma 2 Antibody (supplied by: Log in to see )

Antigen
Phospholipase C gamma 2 (PLCG2) Antibodies
  • APLAID
  • FCAS3
  • Plcg-2
  • PLCgamma2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
193
118
114
6
Host
Rabbit
187
6
Clonality
Polyclonal
Conjugate
This Phospholipase C gamma 2 antibody is un-conjugated
4
4
3
3
3
3
3
3
3
3
3
3
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
115
72
34
34
28
27
14
5
3
2
1
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Catalog No. ABIN271905
$ 390.50
Plus shipping costs $45.00

Similar anti-Phospholipase C gamma 2 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 16 Antibodies 16 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 2 Antibodies 2 Antibodies
Immunofluorescence (IF) 22 Antibodies 23 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 34 Antibodies 34 Antibodies
Immunohistochemistry (IHC) 44 Antibodies 46 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 19 Antibodies 19 Antibodies
Immunoprecipitation (IP) 5 Antibodies 5 Antibodies
Intracellular Staining (ICS) 3 Antibodies 3 Antibodies
Western Blotting (WB) 64 Antibodies 66 Antibodies

General

Antigen Phospholipase C gamma 2 (PLCG2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(193), (118), (114), (6)
Host Rabbit
(187), (6)
Clonality
Polyclonal
Conjugate This Phospholipase C gamma 2 antibody is un-conjugated
(4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(115), (72), (34), (34), (28), (27), (14), (5), (3), (2), (1)
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Product Details anti-Phospholipase C gamma 2 Antibody

Target Details Phospholipase C gamma 2 Application Details Handling Images
Specificity This antibody detects endogenous levels of PLCG2 protein. (region surrounding Arg747)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography using epitope-specific immunogen

Target Details Phospholipase C gamma 2

Product Details anti-Phospholipase C gamma 2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PLCG2 (PLCG2 Antibody Abstract)
Background Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. There are many mammalian PLC isozymes, including PLC β1, PLC β2, PLC β3, PLC β4, PLCγ1, PLCγ2, PLC δ1, PLC δ2 and PLCe. PLCδ exists as four different isoforms. PLC δ1, a calcium signal amplifier, is activated by an atypical GTP-binding protein. In addition, PLC δ1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and α1B-adrenoreceptor signaling. Mouse PLC δ1 is highly expressed in brain, heart, lung and testis. PLC δ is abnormally accumulated in autopsied brains with Alzheimer's disease (AD), suggesting that it may play a role in the pathology of AD. PLC δ2 is markedly expressed in type II intestinal metaplasia and in the adenocarcinoma. When PLC δ2 is expressed in type I intestinal metaplasia, the metaplasia is generally considered benignant, yet evolves toward neoplastic transformation. Thus, PLC δ2 expression may be a possible marker of gastric malignant transformation.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2
Molecular Weight approx. 148 kDa
Gene ID 5336
NCBI Accession NP_002652
UniProt P16885
Pathways RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Handling Images back to top
Application Notes ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Phospholipase C gamma 2 Antibody Target Details Phospholipase C gamma 2 Application Details Handling back to top
Supplier Images
 image for anti-Phospholipase C gamma 2 antibody (PLCG2) (ABIN271905) anti-Phospholipase C gamma 2 (PLCG2) antibody
 image for anti-Phospholipase C gamma 2 antibody (PLCG2) (ABIN271905) anti-Phospholipase C gamma 2 (PLCG2) antibody (Image 2)