Phospholipase C gamma 2 antibody (pTyr753)
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- Target See all Phospholipase C gamma 2 (PLCG2) Antibodies
- Phospholipase C gamma 2 (PLCG2)
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Binding Specificity
- pTyr753
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Phospholipase C gamma 2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of tyrosine 753 (S-L-Y(p)-D-V) derived from Human PLCg2.
- Isotype
- IgG
- Top Product
- Discover our top product PLCG2 Primary Antibody
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- Application Notes
- WB:1:500-1:1000, IF:1:100-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Phospholipase C gamma 2 (PLCG2)
- Alternative Name
- PLCG2 (PLCG2 Products)
- Synonyms
- PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
- Background
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Background: The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Kim YJ, et al. (2004) Mol Cell Biol 24: 9986-9999
Humphries LA, et al. (2004) J Biol Chem 279 : 37651-37661
Suzuki-Inoue K, et al. (2004) Biochem J 378 : 1023-1029
Rodriguez R, et al. (2003) Biochem J 374 : 269-280Aliases: 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2 antibody, 1-phosphatidylinositol-4 antibody, 5-bisphosphate phosphodiesterase gamma-2 antibody, EC 3.1.4.11 antibody, Phosphoinositide phospholipase C antibody, Phosphoinositide phospholipase C-gamma-2 antibody, Phospholipase C gamma 2 antibody, Phospholipase C, gamma 2 (phosphatidylinositol specific) antibody, Phospholipase C-gamma-2 antibody, Phospholipase C-IV antibody, PLC 2 antibody, PLC gamma 2 antibody, PLC IV antibody, PLC-gamma-2 antibody, PLC-IV antibody, Plcg2 antibody, PLCG2_HUMAN antibody
- UniProt
- P16885
- Pathways
- RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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