anti-Human PPP3CC antibody for Enzyme Immunoassay

Recommended PPP3CC Antibody (supplied by: Log in to see )

Antigen
Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC) Antibodies
  • ppp3cc
  • sb:cb767
  • si:dkey-21k4.5
  • calna3
  • cna3
  • pp2bgamma
  • Calnc
  • CALNA3
  • CNA3
  • PP2Bgamma
  • protein phosphatase 3, catalytic subunit, gamma isozyme
  • protein phosphatase 3, catalytic subunit, gamma isozyme, a
  • protein phosphatase 3, catalytic subunit, gamma isoform
  • PPP3CC
  • ppp3cca
  • ppp3cc
  • Ppp3cc
Epitope
AA 480-509, C-Term
17
15
5
4
4
2
2
2
2
1
1
1
1
1
Reactivity
Human
52
6
6
2
2
2
2
1
1
1
Host
Rabbit
50
2
Clonality
Polyclonal
Conjugate
This PPP3CC antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
48
27
24
13
3
1
1
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Catalog No. ABIN360813
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN360812 EIA IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 5
1 ABIN954277 EIA IHC (p) WB Rabbit Ig AA 17-45, N-Term Log in to see Polyclonal 3
1 ABIN784224 EIA IHC (p) WB Rabbit N-Term Log in to see Polyclonal

Top referenced anti-PPP3CC antibody for Enzyme Immunoassay

Similar anti-PPP3CC Antibodies

Application / Reactivity Human
ELISA 27 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunohistochemistry (IHC) 24 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies
Western Blotting (WB) 49 Antibodies

General

Antigen Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC) Antibodies
Epitope AA 480-509, C-Term
(17), (15), (5), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(52), (6), (6), (2), (2), (2), (2), (1), (1), (1)
Host Rabbit
(50), (2)
Clonality
Polyclonal
Conjugate This PPP3CC antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(48), (27), (24), (13), (3), (1), (1)
Pubmed 5 references available
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Product Details anti-PPP3CC Antibody

Target Details PPP3CC Application Details Handling ProductDetails: References for anti-PPP3CC antibody (ABIN360813) Images
Specificity This antibody recognizes PPP3CC.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide between 480~509 amino acids from the C-terminal region of Human PPP3CC.
Isotype Ig

Target Details PPP3CC

Product Details anti-PPP3CC Antibody Application Details Handling ProductDetails: References for anti-PPP3CC antibody (ABIN360813) Images back to top
Antigen
Alternative Name PPP3CC / CALNA3 (PPP3CC Antibody Abstract)
Background Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma, have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).Synonyms: CAM-PRP catalytic subunit, CNA3, Calcineurin testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, protein phosphatase 2B catalytic subunit gamma
Gene ID 5533
NCBI Accession NP_005596
UniProt P48454
Pathways RTK Signaling, WNT Signaling

Application Details

Product Details anti-PPP3CC Antibody Target Details PPP3CC Handling ProductDetails: References for anti-PPP3CC antibody (ABIN360813) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PPP3CC Antibody Target Details PPP3CC Application Details ProductDetails: References for anti-PPP3CC antibody (ABIN360813) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-PPP3CC antibody (ABIN360813)

Product Details anti-PPP3CC Antibody Target Details PPP3CC Application Details Handling Images back to top
Background publications

Eastwood, Burnet, Harrison: "Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia." in: Biological psychiatry, Vol. 57, Issue 7, pp. 702-10, 2005

Gerber, Hall, Miyakawa, Demars, Gogos, Karayiorgou, Tonegawa: "Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8993-8, 2003

Bennasser, Badou, Tkaczuk, Bahraoui: "Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha." in: Virology, Vol. 303, Issue 1, pp. 174-80, 2002

Esau, Boes, Youn, Tatterson, Liu, Chen: "Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells." in: The Journal of experimental medicine, Vol. 194, Issue 10, pp. 1449-59, 2001

Muramatsu, Kincaid: "Molecular cloning and chromosomal mapping of the human gene for the testis-specific catalytic subunit of calmodulin-dependent protein phosphatase (calcineurin A)." in: Biochemical and biophysical research communications, Vol. 188, Issue 1, pp. 265-71, 1992

Images

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Supplier Images
 image for anti-PPP3CC antibody (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme) (AA 480-509) (ABIN360813) anti-Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC) (AA 480-509), (C-Term) antibody
 image for anti-PPP3CC antibody (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme) (AA 480-509) (ABIN360813) anti-Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC) (AA 480-509), (C-Term) antibody (Image 2)