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anti-Human PPP3CC antibody for Enzyme Immunoassay

Recommended PPP3CC Antibody (supplied by: Log in to see )

Antigen
Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC) Antibodies
  • calna3
  • CALNA3
  • Calnc
  • CNA3
  • cna3
  • PP2Bgamma
  • pp2bgamma
  • ppp3cc
  • sb:cb767
  • si:dkey-21k4.5
Epitope
AA 480-509, C-Term
25
16
6
2
2
2
2
1
1
1
1
Reactivity
Human
53
5
5
Host
Rabbit
51
2
Clonality
Polyclonal
Conjugate
This PPP3CC antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
50
27
26
12
3
1
1
Supplier
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Catalog No. ABIN360813
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.000885838 ABIN360812 EIA IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 5
0.000885838 ABIN954277 EIA IHC (p) WB Rabbit Ig AA 17-45, N-Term Log in to see Polyclonal 3
0.000885838 ABIN784224 EIA IHC (p) WB Rabbit N-Term Log in to see Polyclonal

Top referenced anti-PPP3CC antibody for Enzyme Immunoassay

Similar anti-PPP3CC Antibodies

Application / Reactivity Human
ELISA 27 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Immunohistochemistry (IHC) 26 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Western Blotting (WB) 52 Antibodies

General

Antigen Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC) Antibodies
Epitope AA 480-509, C-Term
(25), (16), (6), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(53), (5), (5)
Host Rabbit
(51), (2)
Clonality
Polyclonal
Conjugate This PPP3CC antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(50), (27), (26), (12), (3), (1), (1)
Pubmed 5 references available
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Product Details anti-PPP3CC Antibody

Target Details PPP3CC Application Details Handling References for anti-PPP3CC Antibody (ABIN360813) Images
Specificity This antibody recognizes PPP3CC.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen KLH conjugated synthetic peptide between 480~509 amino acids from the C-terminal region of Human PPP3CC.
Isotype Ig

Target Details PPP3CC

Product Details anti-PPP3CC Antibody Application Details Handling References for anti-PPP3CC Antibody (ABIN360813) Images back to top
Antigen
Alternative Name PPP3CC / CALNA3 (PPP3CC Antibody Abstract)
Background Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma, have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).Synonyms: CAM-PRP catalytic subunit, CNA3, Calcineurin testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, protein phosphatase 2B catalytic subunit gamma
Gene ID 5533
NCBI Accession NP_005596
UniProt P48454
Pathways RTK Signaling, WNT Signaling

Application Details

Product Details anti-PPP3CC Antibody Target Details PPP3CC Handling References for anti-PPP3CC Antibody (ABIN360813) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PPP3CC Antibody Target Details PPP3CC Application Details References for anti-PPP3CC Antibody (ABIN360813) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-PPP3CC Antibody (ABIN360813)

Product Details anti-PPP3CC Antibody Target Details PPP3CC Application Details Handling Images back to top
Background publications

Eastwood, Burnet, Harrison: "Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia." in: Biological psychiatry, Vol. 57, Issue 7, pp. 702-10, 2005

Gerber, Hall, Miyakawa, Demars, Gogos, Karayiorgou, Tonegawa: "Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 15, pp. 8993-8, 2003

Bennasser, Badou, Tkaczuk, Bahraoui: "Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha." in: Virology, Vol. 303, Issue 1, pp. 174-80, 2002

Esau, Boes, Youn, Tatterson, Liu, Chen: "Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells." in: The Journal of experimental medicine, Vol. 194, Issue 10, pp. 1449-59, 2001

Muramatsu, Kincaid: "Molecular cloning and chromosomal mapping of the human gene for the testis-specific catalytic subunit of calmodulin-dependent protein phosphatase (calcineurin A)." in: Biochemical and biophysical research communications, Vol. 188, Issue 1, pp. 265-71, 1992

Images

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Supplier Images
 image for anti-PPP3CC antibody (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme) (AA 480-509) (ABIN360813) anti-Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC) (AA 480-509), (C-Term) antibody
 image for anti-PPP3CC antibody (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme) (AA 480-509) (ABIN360813) anti-Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC) (AA 480-509), (C-Term) antibody (Image 2)