PPP3CC antibody (AA 18-47)

Catalog No. ABIN3032390

Product Details anti-PPP3CC Antibody

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Binding Specificity: AA 18-47

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3CC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogen: A portion of amino acids 18-47 from the human protein was used as the immunogen for this PPP3CC antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PPP3CC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PPP3CC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PPP3CC

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Alternative Name: PPP3CC (PPP3CC Products)

Synonyms: CALNA3 antibody, CNA3 antibody, PP2Bgamma antibody, Calnc antibody, ppp3cc antibody, sb:cb767 antibody, si:dkey-21k4.5 antibody, calna3 antibody, cna3 antibody, pp2bgamma antibody, im:7163784 antibody, zgc:158685 antibody, protein phosphatase 3 catalytic subunit gamma antibody, protein phosphatase 3, catalytic subunit, gamma isoform antibody, protein phosphatase 3, catalytic subunit, gamma isozyme, a antibody, protein phosphatase 3, catalytic subunit, gamma isozyme antibody, protein phosphatase 3, catalytic subunit, gamma isozyme L homeolog antibody, protein phosphatase 3, catalytic subunit, gamma isozyme, b antibody, PPP3CC antibody, Ppp3cc antibody, ppp3cca antibody, ppp3cc antibody, ppp3cc.L antibody, ppp3ccb antibody

Background: Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).

UniProt: P48454

Pathways: RTK Signaling, WNT Signaling, VEGF Signaling, BCR Signaling