anti-Human ROR2 antibody for Enzyme Immunoassay

Recommended ROR2 Antibody (supplied by: Log in to see )

Antigen
Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) Antibodies
  • ROR2
  • bdb
  • bdb1
  • Xror2
  • ntrkr2
  • MGC97773
  • LOC100219935
  • BDB
  • BDB1
  • NTRKR2
  • Ntrkr2
  • mRor2
  • receptor tyrosine kinase-like orphan receptor 2
  • ROR2
  • ror2
  • LOC100219935
  • LOC100351121
  • Ror2
Reactivity
Human
103
13
7
4
4
3
2
1
1
1
1
Host
Rabbit
80
23
1
Clonality
Polyclonal
Conjugate
This ROR2 antibody is un-conjugated
7
6
5
5
4
4
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
80
51
49
34
10
9
2
1
1
1
1
1
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Catalog No. ABIN359932
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5552250 EIA Rabbit Ig Fraction N-Term Log in to see Polyclonal

Top referenced anti-ROR2 antibody for Enzyme Immunoassay

Similar anti-ROR2 Antibodies

Application / Reactivity Human
Cytometry by Time of Flight (CyTOF) 1 Antibodies
ELISA 49 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 34 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunohistochemistry (IHC) 51 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies
Immunoprecipitation (IP) 10 Antibodies
Western Blotting (WB) 80 Antibodies

General

Antigen Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) Antibodies
Reactivity Human
(103), (13), (7), (4), (4), (3), (2), (1), (1), (1), (1)
Host Rabbit
(80), (23), (1)
Clonality
Polyclonal
Conjugate This ROR2 antibody is un-conjugated
(7), (6), (5), (5), (4), (4), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(80), (51), (49), (34), (10), (9), (2), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-ROR2 Antibody

Target Details ROR2 Application Details Handling ProductDetails: References for anti-ROR2 antibody (ABIN359932) Images
Specificity This antibody reacts to ROR2.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a recombinant protein of human ROR2.
Isotype Ig

Target Details ROR2

Product Details anti-ROR2 Antibody Application Details Handling ProductDetails: References for anti-ROR2 antibody (ABIN359932) Images back to top
Antigen
Alternative Name ROR2 (ROR2 Antibody Abstract)
Background ROR2 is a tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. This Type I membrane protein is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Defects in ROR2 are a cause of brachydactyly type B1 (BDB1). BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent. Both fingers and toes are affected. The thumbs and big toes are usually deformed. Defects in ROR2 are a cause of recessive Robinow syndrome (RRS). RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance. The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.Synonyms: NTRKR2, Tyrosine-protein kinase transmembrane receptor ROR2
Gene ID 4920, 9606
UniProt Q01974
Research Area Stem Cells, Extracellular Matrix, Tyrosine Kinases
Pathways RTK Signaling, WNT Signaling

Application Details

Product Details anti-ROR2 Antibody Target Details ROR2 Handling ProductDetails: References for anti-ROR2 antibody (ABIN359932) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-ROR2 Antibody Target Details ROR2 Application Details ProductDetails: References for anti-ROR2 antibody (ABIN359932) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-ROR2 antibody (ABIN359932)

Product Details anti-ROR2 Antibody Target Details ROR2 Application Details Handling Images back to top
Background publications

Afzal, Rajab, Fenske, Oldridge, Elanko, Ternes-Pereira, Tüysüz, Murday, Patton, Wilkie, Jeffery: "Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2." in: Nature genetics, Vol. 25, Issue 4, pp. 419-22, 2000

Oldridge, Fortuna, Maringa, Propping, Mansour, Pollitt, DeChiara, Kimble, Valenzuela, Yancopoulos, Wilkie: "Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B." in: Nature genetics, Vol. 24, Issue 3, pp. 275-8, 2000

van Bokhoven, Celli, Kayserili, van Beusekom, Balci, Brussel, Skovby, Kerr, Percin, Akarsu, Brunner: "Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome." in: Nature genetics, Vol. 25, Issue 4, pp. 423-6, 2000

Schwabe, Tinschert, Buschow, Meinecke, Wolff, Gillessen-Kaesbach, Oldridge, Wilkie, Kömec, Mundlos: "Distinct mutations in the receptor tyrosine kinase gene ROR2 cause brachydactyly type B." in: American journal of human genetics, Vol. 67, Issue 4, pp. 822-31, 2000

Masiakowski, Carroll: "A novel family of cell surface receptors with tyrosine kinase-like domain." in: The Journal of biological chemistry, Vol. 267, Issue 36, pp. 26181-90, 1993

Images

Product Details anti-ROR2 Antibody Target Details ROR2 Application Details Handling ProductDetails: References for anti-ROR2 antibody (ABIN359932) back to top
Supplier Images
 image for anti-ROR2 antibody (Receptor Tyrosine Kinase-Like Orphan Receptor 2) (ABIN359932) anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) antibody
 image for anti-ROR2 antibody (Receptor Tyrosine Kinase-Like Orphan Receptor 2) (ABIN359932) anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) antibody (Image 2)