anti-Human ROR2 antibody for Flow Cytometry

Recommended ROR2 Antibody (supplied by: Log in to see )

Antigen
Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) Antibodies
  • ROR2
  • bdb
  • bdb1
  • Xror2
  • ntrkr2
  • MGC97773
  • LOC100219935
  • BDB
  • BDB1
  • NTRKR2
  • Ntrkr2
  • mRor2
  • receptor tyrosine kinase-like orphan receptor 2
  • ROR2
  • ror2
  • LOC100219935
  • LOC100351121
  • Ror2
Epitope
AA 19-50, N-Term
23
20
19
18
14
6
6
5
4
3
3
2
2
1
1
1
1
1
Reactivity
Human
158
25
13
4
4
3
2
1
1
1
1
Host
Rabbit
98
60
1
Clonality
Polyclonal
Conjugate
This ROR2 antibody is un-conjugated
10
9
8
7
7
6
5
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
125
64
55
51
10
9
2
2
1
1
1
1
Options
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Catalog No. ABIN392044
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.052211 ABIN4897141 FACS Allophycocyanin Mouse IgG1 AA 28-403 Log in to see 231512
14.052211 ABIN4897142 FACS Alexa Fluor 488 Mouse IgG1 AA 28-403 Log in to see 231512
14.052211 ABIN4897140 FACS PE Mouse IgG2a AA 28-403 Log in to see 231509
14.052211 ABIN4897138 FACS Allophycocyanin Mouse IgG2a AA 28-403 Log in to see 231509
14.052211 ABIN4897139 FACS Alexa Fluor 488 Mouse IgG2a AA 28-403 Log in to see 231509
14.052211 ABIN4350966 CyTOF ELISA FACS WB Mouse IgG1 Log in to see 6F2D10
14.052211 ABIN4350967 FACS IHC (p) WB Rabbit N-Term Log in to see Polyclonal
14.052211 ABIN3032442 FACS IHC ELISA WB Rabbit Ig Fraction AA 19-50 Log in to see Polyclonal
14.052211 ABIN5503308 FACS Mouse IgG2a AA 28-403 Log in to see 231509
14.052211 ABIN2683012 FACS ELISA WB Mouse IgG1 AA 59-155 Log in to see 6F2D10
1 ABIN1981349 FACS IHC WB Rabbit IgG AA 19-50, N-Term Log in to see Polyclonal
1 ABIN4881242 ELISA FACS WB Mouse IgG1 AA 59-155 Log in to see 6F2D10
1 ABIN1832361 FACS APC Mouse IgG2a Log in to see 11n166
1 ABIN1832362 FACS PE Mouse IgG2a Log in to see 11n166
1 ABIN1931442 FACS IHC ELISA WB Biotin Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN1931443 FACS IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN1931444 FACS IHC ELISA WB FITC Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN1931441 FACS IHC ELISA WB APC Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN1931445 FACS IHC ELISA WB PE Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN5534648 FACS IHC (p) WB Rabbit Ig Fraction AA 19-50, N-Term Log in to see Polyclonal

General

Antigen Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) Antibodies
Epitope AA 19-50, N-Term
(23), (20), (19), (18), (14), (6), (6), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(158), (25), (13), (4), (4), (3), (2), (1), (1), (1), (1)
Host Rabbit
(98), (60), (1)
Clonality (Clone)
Polyclonal   ( )
Conjugate This ROR2 antibody is un-conjugated
(10), (9), (8), (7), (7), (6), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(125), (64), (55), (51), (10), (9), (2), (2), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-ROR2 Antibody

Target Details ROR2 Application Details Handling References for anti-ROR2 antibody (ABIN392044) Images
Specificity This ROR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27~57 amino acids from the N-terminal region of human ROR2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This ROR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-50 AA from the N-terminal region of human ROR2.
Clone RB01507-01508
Isotype Ig

Target Details ROR2

Product Details anti-ROR2 Antibody Application Details Handling References for anti-ROR2 antibody (ABIN392044) Images back to top
Antigen
Alternative Name ROR2 (ROR2 Antibody Abstract)
Background ROR2 is a tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. This Type I membrane protein is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Defects in ROR2 are a cause of brachydactyly type B1 (BDB1). BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent. Both fingers and toes are affected. The thumbs and big toes are usually deformed. Defects in ROR2 are a cause of recessive Robinow syndrome (RRS). RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance. The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.
Synonyms: Tyrosine-protein kinase transmembrane receptor ROR2, Neurotrophic tyrosine kinase, receptor-related 2 NTRKR2
Molecular Weight 104726 Da
Gene ID 4920
UniProt Q01974
Research Area Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Structure
Pathways RTK Signaling, WNT Signaling

Application Details

Product Details anti-ROR2 Antibody Target Details ROR2 Handling References for anti-ROR2 antibody (ABIN392044) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-ROR2 Antibody Target Details ROR2 Application Details References for anti-ROR2 antibody (ABIN392044) Images back to top
Format Liquid
Concentration 1.57 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-ROR2 antibody (ABIN392044)

Product Details anti-ROR2 Antibody Target Details ROR2 Application Details Handling Images back to top
Product cited in:

Ma, Henry, Llamosas, Higgins, Daniels, Hesson, Hawkins, Ward, Ford: "Validation of specificity of antibodies for immunohistochemistry: the case of ROR2." in: Virchows Archiv : an international journal of pathology, 2016

OConnell, Fiori, Xu, Carter, Frank, Camilli, French, Dissanayake, Indig, Bernier, Taub, Hewitt, Weeraratna: "The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma." in: Oncogene, Vol. 29, Issue 1, pp. 34-44, 2010

Background publications

Afzal, Rajab, Fenske, Oldridge, Elanko, Ternes-Pereira, Tüysüz, Murday, Patton, Wilkie, Jeffery: "Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2." in: Nature genetics, Vol. 25, Issue 4, pp. 419-22, 2000

Oldridge, Fortuna, Maringa, Propping, Mansour, Pollitt, DeChiara, Kimble, Valenzuela, Yancopoulos, Wilkie: "Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B." in: Nature genetics, Vol. 24, Issue 3, pp. 275-8, 2000

van Bokhoven, Celli, Kayserili, van Beusekom, Balci, Brussel, Skovby, Kerr, Percin, Akarsu, Brunner: "Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome." in: Nature genetics, Vol. 25, Issue 4, pp. 423-6, 2000

Schwabe, Tinschert, Buschow, Meinecke, Wolff, Gillessen-Kaesbach, Oldridge, Wilkie, Kömec, Mundlos: "Distinct mutations in the receptor tyrosine kinase gene ROR2 cause brachydactyly type B." in: American journal of human genetics, Vol. 67, Issue 4, pp. 822-31, 2000

Masiakowski, Carroll: "A novel family of cell surface receptors with tyrosine kinase-like domain." in: The Journal of biological chemistry, Vol. 267, Issue 36, pp. 26181-90, 1993

Images

Product Details anti-ROR2 Antibody Target Details ROR2 Application Details Handling References for anti-ROR2 antibody (ABIN392044) back to top
Supplier Images
Western Blotting (WB) image for anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 19-50), (N-Term) antibody (ABIN392044) Western blot analysis of ROR2 (arrow) using rabbit polyclonal ROR2 Antibody (N-term) ...
Immunohistochemistry (IHC) image for anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 19-50), (N-Term) antibody (ABIN392044) Formalin-fixed and paraffin-embedded human kidney carcionma reacted with ROR2 Antibod...
Flow Cytometry (FACS) image for anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 19-50), (N-Term) antibody (ABIN392044) Flow cytometric analysis of NCI-H292 cells using ROR2 Antibody (N-term)(bottom histog...