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Browse our anti-RYK (RYK) Antibodies

Full name:
anti-RYK Receptor-Like Tyrosine Kinase Antibodies (RYK)
On www.antibodies-online.com are 102 RYK Receptor-Like Tyrosine Kinase (RYK) Antibodies from 13 different suppliers available. Additionally we are shipping RYK Proteins (10) and RYK Kits (2) and many more products for this protein. A total of 120 RYK products are currently listed.
Synonyms:
AW536699, D3S3195, ERK-3, JTK5, JTK5A, MGC114645, RYK, RYK1, Vik, wu:fb37b12, wu:fi05b06, zgc:158381
list all antibodies Gene Name GeneID UniProt
RYK 6259 P34925
RYK 20187 Q01887
RYK 140585  

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Most Popular Reactivities for anti-RYK (RYK) Antibodies

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anti-Human RYK Antibodies:

anti-Mouse (Murine) RYK Antibodies:

anti-Rat (Rattus) RYK Antibodies:

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Top referenced anti-RYK Antibodies

  1. Human Polyclonal RYK Primary Antibody for EIA, IHC (p) - ABIN359937 : Trivier, Ganesan: RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN359937

  2. Human Polyclonal RYK Primary Antibody for EIA, WB - ABIN453358 : Wang, Katso, Butler, Hanby, Poulsom, Jones, Sheer, Ganesan: H-RYK, an unusual receptor kinase: isolation and analysis of expression in ovarian cancer. in Molecular medicine (Cambridge, Mass.) 1996 (PubMed)
    Show all 3 references for ABIN453358

  3. Human Polyclonal RYK Primary Antibody for IHC (p), WB - ABIN392050 : Miyashita, Koda, Kitajo, Yamazaki, Takahashi, Kikuchi, Yamashita: Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury. in Journal of neurotrauma 2009 (PubMed)
    Show all 2 references for ABIN392050

  4. Human Polyclonal RYK Primary Antibody for IHC (p), WB - ABIN392051 : Keeble, Halford, Seaman, Kee, Macheda, Anderson, Stacker, Cooper: The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)

  5. Human Monoclonal RYK Primary Antibody for WB - ABIN264516 : Graham, Dawson, Mullaney, Snodgrass, Earp: Cloning and mRNA expression analysis of a novel human protooncogene, c-mer. in Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994 (PubMed)

More Antibodies against RYK Interaction Partners

Zebrafish RYK Receptor-Like Tyrosine Kinase (RYK) interaction partners

  1. RYK and VANGL2 (show VANGL2 Antibodies) proteins form a complex, whereas RYK also activated RhoA (show RHOA Antibodies), a downstream effector of PCP (show PRCP Antibodies) signaling.

  2. Data suggest that full-length Ryk conveys Wnt5b (show WNT5B Antibodies) signals in a directional manner during gastrulation.

Human RYK Receptor-Like Tyrosine Kinase (RYK) interaction partners

  1. results corroborated previous findings of Ryk-mediated Wnt5a (show WNT5A Antibodies) effect, and suggested a role for Ror2 (show ROR2 Antibodies) in the Wnt5a (show WNT5A Antibodies) machinery in glioblastoma

  2. Early treatment with HGF (show HGF Antibodies)/IgG complexes after myocardial ischaemia with reperfusion may rescue tissue through vasoprotection conferred by c-Met and RYK signalling

  3. Ryk-intracellular domain pathway may impair FOXO (show FOXO3 Antibodies) protective activity in mutant polyglutamine neurons, suggesting neurons unable to efficiently maintain function and resist disease from the earliest phases of the pathogenic process in Huntington disease (show HTT Antibodies)

  4. is a candidate wnt5a (show WNT5A Antibodies) receptor.

  5. The Ryk is important for the Wnt-5a (show WNT5A Antibodies)-dependent induction of MMP-2 (show MMP2 Antibodies) and invasive activity in glioma-derived cells and that Ryk might have a novel patho-physiological function in adult cancer invasion.

  6. RYK and VANGL2 (show VANGL2 Antibodies) proteins form a complex, whereas RYK also activated RhoA (show RHOA Antibodies), a downstream effector of PCP (show PRCP Antibodies) signaling.

  7. RYK interacts both physically and functionally with the E3 ubiquitin MIB1. MIB1 is sufficient to activate Wnt (show WNT2 Antibodies)/CTNNB1 (show CTNNB1 Antibodies) signaling and this activity depends on endogenous RYK.

  8. RYK, a catalytically inactive receptor tyrosine kinase (show RET Antibodies), associates with EphB2 (show EPHB2 Antibodies) and EphB3 (show EPHB3 Antibodies) but does not interact with AF-6 (show MLLT4 Antibodies).

Mouse (Murine) RYK Receptor-Like Tyrosine Kinase (RYK) interaction partners

  1. Ryk-intracellular domain pathway may impair FOXO (show FOXO3 Antibodies) protective activity in mutant polyglutamine neurons, suggesting neurons unable to efficiently maintain function and resist disease from the earliest phases of the pathogenic process in Huntington disease (show HTT Antibodies)

  2. Wnt5a (show WNT5A Antibodies) regulates HSC (show FUT1 Antibodies) quiescence and hematopoietic repopulation through the Ryk receptor and that this process is mediated by suppression of reactive oxygen species.

  3. Ryk inhibits axonal growth in response to Wnt5a (show WNT5A Antibodies).

  4. Ryk is an important mediator of ventral midbrain dopaminergic neuron development.

  5. Ryk regulates Wnt5a (show WNT5A Antibodies) signaling and planar cell polarity by modulating the degradation of Vangl2 (show VANGL2 Antibodies).

  6. RYK and VANGL2 (show VANGL2 Antibodies) proteins form a complex, whereas RYK also activated RhoA (show RHOA Antibodies), a downstream effector of PCP (show BMP1 Antibodies) signaling.

  7. Results identify Ryk as a multi-functional receptor that is able to transduce extrinsic cues into progenitor cells, promote GABAergic neuron formation, and inhibit oligodendrogenesis during ventral embryonic brain development.

  8. Mammalian Ryk, unlike the Drosophila Ryk homolog Derailed, functions as a coreceptor along with Frizzled for Wnt (show WNT2 Antibodies) ligands.

  9. RYK regulates cell migration during mammalian cortical development through the binding to Eph (show EPHA1 Antibodies) receptors

  10. Wnt3 (show WNT3 Antibodies) repulsion is mediated by Ryk, expressed in a ventral-to-dorsal decreasing gradient

RYK Antigen Profile

Antigen Summary

The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with RYK

  • RYK receptor-like tyrosine kinase (RYK) antibody
  • ryk receptor-like tyrosine kinase (ryk) antibody
  • receptor-like tyrosine kinase (ryk) antibody
  • receptor-like tyrosine kinase (RYK) antibody
  • RYK receptor-like tyrosine kinase (ryk) antibody
  • receptor-like tyrosine kinase (Ryk) antibody
  • AW536699 antibody
  • D3S3195 antibody
  • ERK-3 antibody
  • JTK5 antibody
  • JTK5A antibody
  • MGC114645 antibody
  • RYK antibody
  • RYK1 antibody
  • Vik antibody
  • wu:fb37b12 antibody
  • wu:fi05b06 antibody
  • zgc:158381 antibody

Protein level used designations for RYK

RYK receptor-like tyrosine kinase , tyrosine kinase RYK , ryk receptor-like tyrosine kinase , receptor-like tyrosine kinase , tyrosine-protein kinase RYK , tyrosine kinase-related protein , tyrosine-protein kinase RYK-like , JTK5A protein tyrosine kinase , hydroxyaryl-protein kinase , NYK-R , growth factor receptor , kinase VIK , met-related kinase

GENE ID SPECIES
395409 Gallus gallus
470931 Pan troglodytes
477074 Canis lupus familiaris
550026 Xenopus (Silurana) tropicalis
558502 Danio rerio
718950 Macaca mulatta
734495 Xenopus laevis
781353 Bos taurus
100008628 Oryctolagus cuniculus
100466026 Ailuropoda melanoleuca
100541106 Meleagris gallopavo
100555132 Anolis carolinensis
100591428 Nomascus leucogenys
6259 Homo sapiens
20187 Mus musculus
140585 Rattus norvegicus
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