RYK Products
(RYK Receptor-Like Tyrosine Kinase (RYK))
Categories
The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012].
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Featured RYK Categories
RYK Antibodies
High quality antibodies with extensive validation data.
RYK ELISA Kits
Reliable ELISA kits for a wide range of species.
RYK Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RYK Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (4)
- (7)
Cat. No.
ABIN392050
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7174060
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (2)
Cat. No.
ABIN392051
Quantity
400 μL
Datasheet
Datasheet
Recommended RYK ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4886279
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4884386
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730510
Quantity
96 tests
Datasheet
Datasheet
Recommended RYK Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319036
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3087682
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3121366
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our RYK products
: "Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor." in: Stem cells (Dayton, Ohio), Vol. 32, Issue 1, pp. 105-15, (2014) (PubMed).: "The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury." in: Journal of neurotrauma, Vol. 30, Issue 10, pp. 806-17, (2013) (PubMed).
: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).
: "Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury." in: Journal of neurotrauma, Vol. 26, Issue 7, pp. 955-64, (2009) (PubMed).
: "The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 21, pp. 5840-8, (2006) (PubMed).
Synonyms and alternative names related to RYK
receptor-like tyrosine kinase (RYK), receptor-like tyrosine kinase (ryk), receptor-like tyrosine kinase S homeolog (ryk.S), tyrosine-protein kinase RYK (LOC100541106), receptor-like tyrosine kinase (Ryk), AW536699, d3s3195, D3S3195, ERK-3, jtk5, JTK5, jtk5a, JTK5A, MGC114645, RYK, ryk1, RYK1, Vik, wu:fb37b12, wu:fi05b06, zgc:158381Protein level used designations for RYK
- RYK receptor-like tyrosine kinase
- tyrosine kinase RYK
- ryk receptor-like tyrosine kinase
- receptor-like tyrosine kinase
- tyrosine-protein kinase RYK
- tyrosine kinase-related protein
- tyrosine-protein kinase RYK-like
- JTK5A protein tyrosine kinase
- hydroxyaryl-protein kinase
- NYK-R
- growth factor receptor
- kinase VIK
- met-related kinase
Did you look for something else?
- RYBP
- Ryanodine Receptor 3
- Ryanodine Receptor
- RXFP4
- RXFP2
- RXFP1
- RWDD4A
- RWDD3
- RWDD2B
- RWDD2A
- RWDD1
- RVFV N
- RVFV L
- RVFV G
- RuvC
- RUVBL2
- RUVBL1
- RuvA
- RUSC2
- RUSC1
- Ryncolin-1-Like
- RYR1
- RYR2
- S-100
- S-Adenosyl-Homocysteine
- S-Adenosyl-Methionine
- S-Adenosyl-Methionine Synthase 2
- S-Adenosyl-Methionine Synthase 4
- S-Ribosylhomocysteine Lyase
- S-Tag
- S1-Tag
- S100 Ab
- S100 Calcium Binding Protein A10
- S100 Calcium Binding Protein A7A
- S100 Protein
- S100A/B
- S100A1
- S100A11
- S100A12
- S100A13
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