anti-Human TIE1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended TIE1 Antibody (supplied by: Log in to see )

Antigen
tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) Antibodies
  • tie-1
  • JTK14
  • TIE
  • D430008P04Rik
  • tyrosine kinase with immunoglobulin like and EGF like domains 1
  • tyrosine-protein kinase receptor Tie-1
  • endothelium-specific receptor tyrosine kinase 1
  • tyrosine kinase with immunoglobulin-like and EGF-like domains 1
  • TIE1
  • CpipJ_CPIJ018933
  • tie1
  • Tie1
Epitope
C-Term
32
18
15
13
12
11
11
8
7
6
5
5
4
3
3
3
2
1
1
1
Reactivity
Human
230
58
29
3
1
Host
Rabbit
124
107
3
1
Clonality
Polyclonal
Conjugate
This TIE1 antibody is un-conjugated
13
10
10
8
6
6
6
5
5
5
5
5
5
5
5
5
4
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
187
146
84
40
33
13
8
8
6
4
2
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN783895
$ 368.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.4242 ABIN1996997 ELISA (Detection) IHC (p) Mouse IgG2b AA 1-760 Log in to see 8D2D2
1 ABIN359947 EIA IHC (p) WB Rabbit Ig Fraction N-Term Log in to see Polyclonal 4
1 ABIN392060 IHC (p) WB Rabbit Ig Fraction AA 12-42, N-Term Log in to see Polyclonal 1
1 ABIN675099 IF (p) IHC (p) WB Rabbit IgG AA 850-900 Log in to see Polyclonal
1 ABIN955206 EIA IHC (p) WB Mouse IgG2a Log in to see 1G10
1 ABIN1689012 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1688127 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN258833 IHC (p) IHC WB Mouse IgG1 Log in to see MM0017-12D9
1 ABIN2855630 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN675108 IHC (p) WB HRP Rabbit IgG AA 850-900 Log in to see Polyclonal
1 ABIN609763 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN675101 IHC (p) WB Biotin Rabbit IgG AA 850-900 Log in to see Polyclonal
1 ABIN961303 IHC (p) ELISA WB Mouse IgG2a, kappa Log in to see 1G10
1 ABIN1740068 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN4359667 IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN4359668 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN2574439 FACS IHC (p) WB Goat IgG AA 22-760 Log in to see Polyclonal
1 ABIN5604066 IHC IHC (p) WB DyLight 755 Mouse IgG1 Log in to see MM0017-12D9
1 ABIN5604056 IHC IHC (p) WB Alexa Fluor 488 Mouse IgG1 Log in to see MM0017-12D9
1 ABIN5604063 IHC IHC (p) WB DyLight 550 Mouse IgG1 Log in to see MM0017-12D9

General

Antigen tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) Antibodies
Epitope C-Term
(32), (18), (15), (13), (12), (11), (11), (8), (7), (6), (5), (5), (4), (3), (3), (3), (2), (1), (1), (1)
Reactivity Human
(230), (58), (29), (3), (1)
Host Rabbit
(124), (107), (3), (1)
Clonality
Polyclonal
Conjugate This TIE1 antibody is un-conjugated
(13), (10), (10), (8), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(187), (146), (84), (40), (33), (13), (8), (8), (6), (4), (2), (2), (1), (1), (1)
Supplier Log in to see

Product Details anti-TIE1 Antibody

Target Details TIE1 Application Details Handling Images
Specificity This antibody reacts to the C-term of Protein Tyrosine Kinase Receptor TIE1.
Purification Immunoaffinity Chromatography
Immunogen Synthetic peptide corresponding to C-terminal of human Tie-1 Genename: TIE1
Isotype IgG

Target Details TIE1

Product Details anti-TIE1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TIE1 (TIE1 Antibody Abstract)
Background TIE1 is a receptor that is implicated in vessel maturation and angiogenesis. TIE1 contains immunoglobulin-like loops and epidermal growth factor (EGF) homology domains. TIE1/TIE (tyrosine kinase with Ig and EGF homology domains 1) and TIE2/Tek define a new class of the receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin like domains flanking three epidermal growth factor (EFG) like domains followed by three fibronectin type III like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. Human TIE1 cDNA encodes a 1138 amino acid residue precursor protein with a putative signal peptide, an extracellular domain, and a cytoplasmic domain. TIE1 and TIE2, expressed primarily on endothelial and hematopoietic progenitor cells, play important roles in angiogenesis, vasculogenesis, and hematopoiesis. In developing vascular endothelial cells, TIE1 and TIE2 are specifically expressed. Two ligands that bind TIE have been identified, angiopoietin 1 and angiopoietin 2. Based on gene targeting studies, the in vivo functions of TIE1 are related to endothelial cell differentiation.Synonyms: TIE, Tie-1, Tyrosine-protein kinase receptor Tie-1
Gene ID 7075
NCBI Accession NP_005415
Research Area Lineage Markers, Tyrosine Kinases
Pathways RTK Signaling

Application Details

Product Details anti-TIE1 Antibody Target Details TIE1 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TIE1 Antibody Target Details TIE1 Application Details Images back to top
Format Liquid
Buffer 10 mM PBS, pH 7.4 containing BSA as stabilizer and 0,09 % sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Images

Product Details anti-TIE1 Antibody Target Details TIE1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (C-Term) antibody (ABIN783895) Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)