anti-Human TIE1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended TIE1 Antibody (supplied by: Log in to see )

Antigen
tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) Antibodies
  • tie-1
  • JTK14
  • TIE
  • D430008P04Rik
  • tyrosine kinase with immunoglobulin-like and EGF-like domains 1
  • tyrosine-protein kinase receptor Tie-1
  • endothelium-specific receptor tyrosine kinase 1
  • TIE1
  • LOC100350418
  • CpipJ_CPIJ018933
  • tie1
  • Tie1
Epitope
AA 1-760
32
18
15
13
13
12
11
8
7
6
5
4
4
4
3
2
1
1
Reactivity
Human
228
56
29
3
Host
Mouse
123
102
4
1
Clonality
Monoclonal
Conjugate
This TIE1 antibody is un-conjugated
13
10
10
8
6
6
5
5
5
5
5
5
5
5
5
4
4
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA (Detection), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
182
143
80
40
33
13
7
6
6
2
2
1
1
Supplier
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Catalog No. ABIN1996997
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.571599 ABIN783895 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN359947 EIA IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 4
1 ABIN392060 IHC (p) WB Rabbit Ig AA 12-42, N-Term Log in to see Polyclonal 1
1 ABIN675099 IF (p) IHC (p) WB Rabbit IgG AA 850-900 Log in to see Polyclonal
1 ABIN1689012 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN955206 EIA IHC (p) WB Mouse IgG2a Log in to see 1G10
1 ABIN1688127 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN2855630 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN258833 IHC (p) IHC WB Mouse IgG1 Log in to see MM0017-12D9
1 ABIN675108 IHC (p) WB HRP Rabbit IgG AA 850-900 Log in to see Polyclonal
1 ABIN609763 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN675101 IHC (p) WB Biotin Rabbit IgG AA 850-900 Log in to see Polyclonal
1 ABIN961303 IHC (p) ELISA WB Mouse IgG2a, kappa Log in to see 1G10
1 ABIN1740068 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN2574439 FACS IHC (p) WB Goat IgG AA 22-760 Log in to see Polyclonal
1 ABIN4359667 IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN4359668 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1723947 IHC (p) ELISA WB Mouse IgG2a kappa Log in to see 1G10
1 ABIN5604059 IHC IHC (p) WB Biotin Mouse IgG1 Log in to see MM0017-12D9
1 ABIN5604060 IHC IHC (p) WB DyLight 350 Mouse IgG1 Log in to see MM0017-12D9

General

Antigen tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) Antibodies
Epitope AA 1-760
(32), (18), (15), (13), (13), (12), (11), (8), (7), (6), (5), (4), (4), (4), (3), (2), (1), (1)
Reactivity Human
(228), (56), (29), (3)
Host Mouse
(123), (102), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TIE1 antibody is un-conjugated
(13), (10), (10), (8), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA (Detection), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(182), (143), (80), (40), (33), (13), (7), (6), (6), (2), (2), (1), (1)
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Product Details anti-TIE1 Antibody

Target Details TIE1 Application Details Handling Images
Specificity Human Tie1
No cross-reactivity in ELISA with
Human Tie2
Human cell lysate (293 cell line)
No Cross-Reactivity Human
Characteristics This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Tie1 (rh Tie1, ABIN2002976 NP_005415.1, Met 1-Gln 760,. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Purification purified by Protein A affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Human Tie1 Protein (ABIN2002976)
Clone 8D2D2
Isotype IgG2b

Target Details TIE1

Product Details anti-TIE1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TIE1 (TIE1 Antibody Abstract)
Background Tyrosine-protein kinase receptor Tie-1, also known as TIE1, is a single-pass type I membrane protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and Tie subfamily. TIE1 contains threeEGF-like domains, threefibronectin type-III domains, twoIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. TIE1 is an endothelial-cell-specific tyrosine kinase receptor. It is a cell surface protein expressed exclusively in endothelial cells. It is required for the survival and growth of microvascular endothelial cells during the capillary sprouting phase of vascular development. TIE1 is an orphan receptor tyrosine kinase that is expressed almost exclusively in endothelial cells and that is required for normal embryonic vascular development. TIE1 upregulates the cell adhesion molecules (CAMs) VCAM-1, E-selectin, and ICAM-1 through a p38-dependent mechanism. Attachment of monocyte derived immune cells to endothelial cells is also enhanced by TIE1 expression. TIE1 has a proinflammatory effect and may play a role in the endothelial inflammatory diseases such as atherosclerosis.
NCBI Accession NP_005415.1
Pathways RTK Signaling

Application Details

Product Details anti-TIE1 Antibody Target Details TIE1 Handling Images back to top
Application Notes ELISA(Det): 0.1-1 μg/mL
IHC-P: 5-20 μg/mL
Restrictions For Research Use only

Handling

Product Details anti-TIE1 Antibody Target Details TIE1 Application Details Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

Images

Product Details anti-TIE1 Antibody Target Details TIE1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 1-760) antibody (ABIN1996997) anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 1-760) antibody
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 1-760) antibody (ABIN1996997) anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 1-760) antibody (Image 2)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 1-760) antibody (ABIN1996997) anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 1-760) antibody (Image 3)