anti-Human VEGFR2 antibody for Neutralization

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • vegfr-2
  • KDR
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • VEGFR2
  • sVEGFR-2
  • Vegfr-2
  • CD309
  • FLK1
  • VEGFR
  • FLK-1
  • flk-1
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • fk52c05
  • flk
  • kdr
  • kdra
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fk52c05
  • vascular endothelial growth factor receptor 2
  • kinase insert domain protein receptor
  • kinase insert domain receptor
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • kinase insert domain receptor like
  • vascular endothelial growth factor receptor-2
  • vegfr-2
  • Kdr
  • KDR
  • kdr
  • kdrl
Epitope
AA 20-764
77
58
53
38
24
23
21
18
18
18
16
16
15
15
13
13
13
12
12
11
10
10
9
7
6
6
6
5
5
4
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
611
372
183
25
7
4
4
4
3
3
2
2
1
1
1
1
1
1
1
1
Host
Mouse
535
140
60
4
2
2
1
Clonality
Monoclonal
Conjugate
This VEGFR2 antibody is un-conjugated
45
32
24
20
18
12
11
9
9
5
5
5
5
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
Application
Flow Cytometry (FACS), Neutralization (Neut)
463
239
208
201
118
109
40
34
26
24
19
17
11
8
8
7
6
5
3
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN4899538
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
34.729786 ABIN4899539 FACS Neut Mouse IgG1 AA 20-764 Log in to see 89106 10
1 ABIN449647 BP ELISA FACS IP Neut WB Biotin Mouse IgG1 Log in to see 4H3
1 ABIN958173 IHC (p) Neut WB Goat IgG AA 20-764 Log in to see Polyclonal
1 ABIN1824313 FACS IP Neut WB Mouse IgG1 Extracellular Domain Log in to see 23B31
1 ABIN1003446 IP Neut ELISA WB Rabbit IgG Log in to see Polyclonal 3
1 ABIN933609 FACS IP Neut WB Mouse IgG1 Extracellular Domain Log in to see 23B31
1 ABIN1003447 IP Neut ELISA WB Mouse IgG Log in to see 4

Top referenced anti-VEGFR2 antibody for Neutralization

  • Human Monoclonal VEGFR2 Primary Antibody for FACS, Neut - ABIN4899538 (10 Publications): Riccioni, Diverio, Mariani, Buffolino, Riti, Saulle, Petrucci, Cedrone, Lo-Coco, Foà, Peschle, Testa: Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. in Stem cells (Dayton, Ohio) 2007 (PubMed)

  • Human Monoclonal VEGFR2 Primary Antibody for FACS, Neut - ABIN4899539 (10 Publications): Riccioni, Senese, Diverio, Riti, Mariani, Boe, LoCoco, Foà, Peschle, Sporn, Testa: Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels. in Leukemia research 2008 (PubMed)

  • Human Polyclonal VEGFR2 Primary Antibody for IP, Neut - ABIN1003446 (3 Publications): Simon, Röckl, Hornig, Gröne, Theis, Weich, Fuchs, Yayon, Gröne: Receptors of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in fetal and adult human kidney: localization and [125I]VEGF binding sites. in Journal of the American Society of Nephrology : JASN 1998 (PubMed)

Similar anti-VEGFR2 Antibodies

Application / Reactivity Human
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Peptide (BP) 1 Antibodies
Cell Culture (CC) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 3 Antibodies
Dot Blot (DB) 17 Antibodies
ELISA 201 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 19 Antibodies
Flow Cytometry (FACS) 147 Antibodies
Functional Studies (Func) 6 Antibodies
Immunochromatography (IC) 8 Antibodies
Immunocytochemistry (ICC) 35 Antibodies
Immunofluorescence (IF) 116 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 8 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies
Immunohistochemistry (IHC) 185 Antibodies

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Epitope AA 20-764
(77), (58), (53), (38), (24), (23), (21), (18), (18), (18), (16), (16), (15), (15), (13), (13), (13), (12), (12), (11), (10), (10), (9), (7), (6), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(611), (372), (183), (25), (7), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(535), (140), (60), (4), (2), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VEGFR2 antibody is un-conjugated
(45), (32), (24), (20), (18), (12), (11), (9), (9), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1)
Application Flow Cytometry (FACS), Neutralization (Neut)
(463), (239), (208), (201), (118), (109), (40), (34), (26), (24), (19), (17), (11), (8), (8), (7), (6), (5), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 10 references available
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Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling ProductDetails: References for anti-VEGFR2 antibody (ABIN4899538) Images
Specificity Detects human VEGF R2/KDR/Flk-1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) VEGF R1, rhVEGF R3 or recombinant mouse VEGF R2 is observed.
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGF R2/KDR/Flk-1, Ala20-Glu764, Accession # P35968
Clone 89106
Isotype IgG1

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling ProductDetails: References for anti-VEGFR2 antibody (ABIN4899538) Images back to top
Antigen
Alternative Name VEGF R2/KDR (KDR Antibody Abstract)
Background Alternative Names: CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, Flk1, Flk-1, FLK1tyrosine kinase growth factor receptor, KDR, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGFR, VEGFR2, VEGFR-2
Gene ID 3791
UniProt P35968
Pathways RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling ProductDetails: References for anti-VEGFR2 antibody (ABIN4899538) Images back to top
Application Notes Flow Cytometry 0.25 μg/10^6 cells
Neutralization 10-50 ng/mL
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details ProductDetails: References for anti-VEGFR2 antibody (ABIN4899538) Images back to top
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

ProductDetails: References for anti-VEGFR2 antibody (ABIN4899538)

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling Images back to top
Product cited in:

Facciabene, Peng, Hagemann, Balint, Barchetti, Wang, Gimotty, Gilks, Lal, Zhang, Coukos: "Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells." in: Nature, Vol. 475, Issue 7355, pp. 226-30, 2011 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Byeon, Lee, Choi, Lee, Lee, Chu, Kwon: "Vascular endothelial growth factor as an autocrine survival factor for retinal pigment epithelial cells under oxidative stress via the VEGF-R2/PI3K/Akt." in: Investigative ophthalmology & visual science, Vol. 51, Issue 2, pp. 1190-7, 2010 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Riccioni, Senese, Diverio, Riti, Mariani, Boe, LoCoco, Foà, Peschle, Sporn, Testa: "Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels." in: Leukemia research, Vol. 32, Issue 8, pp. 1244-58, 2008 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ohsaka, Hirota-Komatsu, Shibata, Ezaki, Shinohara, Yoshida: "Specific association of increased vascular endothelial growth factor expression and its receptors with macrophage differentiation of HL-60 leukemia cells." in: Biochemical and biophysical research communications, Vol. 368, Issue 3, pp. 543-9, 2008 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Riccioni, Diverio, Mariani, Buffolino, Riti, Saulle, Petrucci, Cedrone, Lo-Coco, Foà, Peschle, Testa: "Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 8, pp. 1862-71, 2007 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Rajesh, Chinnasamy, Mitalipov, Wolf, Slukvin, Thomson, Shaaban: "Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 2, pp. 490-9, 2007 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ball, Shuttleworth, Kielty: "Vascular endothelial growth factor can signal through platelet-derived growth factor receptors." in: The Journal of cell biology, Vol. 177, Issue 3, pp. 489-500, 2007 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Lin, Liang, Chiang: "Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells." in: Journal of leukocyte biology, Vol. 82, Issue 6, pp. 1473-80, 2007 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Caldas, Fangusaro, Boué, Holloway, Altura: "Dissecting the role of endothelial SURVIVIN DeltaEx3 in angiogenesis." in: Blood, Vol. 109, Issue 4, pp. 1479-89, 2007 Method employed by authors: Neutralization (Neut) (Sample species: Human).

Sreekumar, Kannan, de Silva, Burton, Ryan, Hinton: "Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells." in: Biochemical and biophysical research communications, Vol. 346, Issue 4, pp. 1200-6, 2006 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Images

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling ProductDetails: References for anti-VEGFR2 antibody (ABIN4899538) back to top
Supplier Images
Neutralization (Neut) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 20-764) (ABIN4899538) VEGF R2/KDR Inhibition of VEGF-dependent Cell Proliferation and Neutralization by Hum...
Flow Cytometry (FACS) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 20-764) (ABIN4899538) Detection of VEGF R2/KDR/Flk-1 in HUVEC Human Cells by Flow Cytometry. HUVEC human um...
Neutralization (Neut) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 20-764) (ABIN4899538) VEGF R2/KDR Inhibition of VEGF-dependent Cell Proliferation and Neutralization by Hum...
Flow Cytometry (FACS) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 20-764) (ABIN4899538) Detection of VEGF R2/KDR/Flk-1 in HUVEC Human Cells by Flow Cytometry. HUVEC human um...