You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Rat (Rattus) VEGFR2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended VEGFR2 Antibody (supplied by: Log in to see )

Antigen
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
  • 6130401C07
  • CD309
  • fk52c05
  • flk
  • FLK-1
  • flk-1
  • Flk-1
  • FLK/KDR
  • Flk1
  • flk1
  • FLK1
  • flk1b
  • kdr
  • KDR
  • kdra
  • kdrb
  • Krd-1
  • Ly73
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • sVEGFR-2
  • VEGFR
  • Vegfr-2
  • vegfr-2
  • VEGFR-2
  • VEGFR2
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fc31a09
  • wu:fk52c05
Epitope
AA 150-190
79
52
50
36
24
20
18
18
17
17
14
13
13
13
12
12
12
10
9
7
6
6
6
6
5
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
537
275
150
5
5
4
3
2
2
2
1
1
1
1
1
1
1
1
1
Host
Rabbit
483
107
51
2
2
2
1
Clonality
Polyclonal
Conjugate
This VEGFR2 antibody is un-conjugated
38
25
22
16
14
12
9
7
5
4
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
403
231
205
126
105
78
31
27
23
22
17
16
8
6
6
5
5
2
2
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN2180045
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34288716 ABIN498218 IF IHC (p) Rabbit Log in to see Polyclonal
0.34288716 ABIN498808 IHC (p) Rabbit pTyr1214 Log in to see Polyclonal
0.34288716 ABIN498807 IHC (p) Rabbit pTyr1175 Log in to see Polyclonal
0.34288716 ABIN498898 IHC (p) Rabbit Log in to see Polyclonal
0.34288716 ABIN498899 IHC (p) Rabbit Log in to see Polyclonal
0.34288716 ABIN2506667 ICC IF IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN181334 IHC (p) WB Rabbit C-Term Log in to see Polyclonal 4
0.0008982679 ABIN115388 IHC (p) Rabbit C-Term Log in to see Polyclonal 1
0.0008982679 ABIN115389 IHC (p) Rabbit C-Term Log in to see Polyclonal 2
0.0008982679 ABIN197238 IF IHC (p) WB Rabbit AA 1212-1216 Log in to see Polyclonal 2
0.0008982679 ABIN197240 IF IHC (p) WB Rabbit AA 949-953 Log in to see Polyclonal 2
0.0008982679 ABIN197236 IF IHC (p) WB Rabbit Tyr1175 Log in to see Polyclonal 2
0.0008982679 ABIN196770 IF IHC (p) WB Rabbit pTyr951 Log in to see Polyclonal 2
0.0008982679 ABIN271859 IHC (p) WB Rabbit Log in to see Polyclonal
0.0008982679 ABIN271860 IHC (p) WB Rabbit Log in to see Polyclonal
0.0008982679 ABIN318151 IHC (p) Rabbit pTyr1175 Log in to see Polyclonal
0.0008982679 ABIN373443 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008982679 ABIN746783 IF (p) IHC (p) WB Rabbit IgG AA 1150-1200, pTyr1175 Log in to see Polyclonal
0.0008982679 ABIN285774 IHC (fro) IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008982679 ABIN257628 ICC IF IHC (p) IHC Rabbit IgG Tyr1175 Log in to see Polyclonal

Top referenced anti-VEGFR2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-VEGFR2 Antibodies

Application / Reactivity Human Rat (Rattus)
Western Blotting (WB) 367 Antibodies 81 Antibodies
Neutralization (Neut) 6 Antibodies
Mass Cytometry (CyTOF) 1 Antibodies
Immunoprecipitation (IP) 22 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 82 Antibodies 32 Antibodies
Immunohistochemistry (IHC) 201 Antibodies 68 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 22 Antibodies 3 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies
Immunofluorescence (IF) 112 Antibodies 43 Antibodies

General

Antigen Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antibodies
Epitope AA 150-190
(79), (52), (50), (36), (24), (20), (18), (18), (17), (17), (14), (13), (13), (13), (12), (12), (12), (10), (9), (7), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(537), (275), (150), (5), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(483), (107), (51), (2), (2), (2), (1)
Clonality
Polyclonal
Conjugate This VEGFR2 antibody is un-conjugated
(38), (25), (22), (16), (14), (12), (9), (7), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(403), (231), (205), (126), (105), (78), (31), (27), (23), (22), (17), (16), (8), (6), (6), (5), (5), (2), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
Supplier Log in to see

Product Details anti-VEGFR2 Antibody

Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 Antibody (ABIN2180045) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human VEGFR2
Isotype IgG

Target Details VEGFR2

Product Details anti-VEGFR2 Antibody Application Details Handling References for anti-VEGFR2 Antibody (ABIN2180045) Images back to top
Antigen
Alternative Name Vegfr2 (KDR Antibody Abstract)
Background

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular growth factors to isoform 1 leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. Required for VEGFA-mediated induction of NOS2 and NOS3, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells. Phosphorylates PLCG1. Promotes phosphorylation of FYN, NCK1, NOS3, PIK3R1, PTK2/FAK1 and SRC.

Subcellular location: Extracellular


Synonyms: FLK1, CD309, VEGFR, VEGFR2, Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1
Gene ID 3791
UniProt P35968
Pathways RTK Signaling

Application Details

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Handling References for anti-VEGFR2 Antibody (ABIN2180045) Images back to top
Application Notes IHC-P(1:100-500)
Restrictions For Research Use only

Handling

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details References for anti-VEGFR2 Antibody (ABIN2180045) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-VEGFR2 Antibody (ABIN2180045)

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling Images back to top
Product cited in:

Tan, Yang, Fu, Cui, Guo, Ma, Yin, Leng, Song: "Single-dose local simvastatin injection improves implant fixation via increased angiogenesis and bone formation in an ovariectomized rat model." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 1428-39, 2015

García Fernández, Sánchez Pérez, Sánchez Maldonado, García-Palencia, Naranjo Freixa, Palomo Yagüe, Flores: "Iberian pig early pregnancy: vascular endothelial growth factor receptor system expression in the maternofetal interface in healthy and arresting conceptuses." in: Theriogenology, Vol. 83, Issue 3, pp. 334-43, 2014

Kuang, Yang, Zhang, Zhang, Wu: "Schlafen 1 inhibits the proliferation and tube formation of endothelial progenitor cells." in: PLoS ONE, Vol. 9, Issue 10, pp. e109711, 2014

Images

Product Details anti-VEGFR2 Antibody Target Details VEGFR2 Application Details Handling References for anti-VEGFR2 Antibody (ABIN2180045) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 150-190) (ABIN2180045) HeLa cells probed with Rabbit Anti-VEGFR2 Polyclonal Antibody (ABIN2180045) at 1:100 ...
Western Blotting (WB) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 150-190) (ABIN2180045) Mouse lung lysates probed with Anti-VEGFR2 Polyclonal Antibody at 1:5000 90min in 37˚C.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (AA 150-190) (ABIN2180045) Formalin-fixed and paraffin embedded mouse placenta tissue labeled with Anti-VEGFR2 P...