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Browse our anti-EYA4 (EYA4) Antibodies

Full name:
anti-Eyes Absent Homolog 4 (Drosophila) Antibodies (EYA4)
On www.antibodies-online.com are 64 Eyes Absent Homolog 4 (Drosophila) (EYA4) Antibodies from 12 different suppliers available. Additionally we are shipping EYA4 Proteins (4) and many more products for this protein. A total of 71 EYA4 products are currently listed.
Synonyms:
B130023L16Rik, CMD1J, DFNA10
list all antibodies Gene Name GeneID UniProt
EYA4 14051  
EYA4 2070 O95677
EYA4 292172  

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Top referenced anti-EYA4 Antibodies

  1. Human Polyclonal EYA4 Primary Antibody for EIA, FACS - ABIN952150 : Miller, Lan, Hardiman, Wu, Kordich, Patmore, Hegde, Cripe, Cancelas, Collins, Ratner: Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis. in Oncogene 2010 (PubMed)

  2. Human Polyclonal EYA4 Primary Antibody for ELISA, WB - ABIN185511 : Schönberger, Wang, Shin, Kim, Depreux, Zhu, Zon, Pizard, Kim, Macrae, Mungall, Seidman, Seidman: Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss. in Nature genetics 2005 (PubMed)

More Antibodies against EYA4 Interaction Partners

Mouse (Murine) Eyes Absent Homolog 4 (Drosophila) (EYA4) interaction partners

  1. results implicate Eya4/Six1 (show SIX1 Antibodies) regulates normal cardiac function via p27 (show CDKN1B Antibodies)/casein kinase-2alpha/histone deacetylase 2 (show HDAC2 Antibodies) and indicate that mutations within this transcriptional complex and signaling cascade lead to the development of cardiomyopathy.

  2. constructs of the homologous region ( Eya1HR and Eya4HR) interact with Six1 (show SIX1 Antibodies) prey constructs, although no interaction with Dach1 (show DACH1 Antibodies) prey was demonstrable

  3. Eya4(-/-) mice developed otitis media with effusion; anatomic studies revealed abnormal middle ear cavity and eustachian tube dysmorphology.

  4. that Eyes absent 4 (EYA4), originally identified as a co-transcription factor, stimulates the expression of IFN-beta (show IFNB1 Antibodies) and CXCL10 (show CXCL10 Antibodies) in response to the undigested DNA of apoptotic cells

Human Eyes Absent Homolog 4 (Drosophila) (EYA4) interaction partners

  1. Up to now, merely 7 loci have been linked to mid-frequency hearing loss. Only four genetic mid-frequency deafness genes, namely, DFNA10 (EYA4), DFNA8 (show TECTA Antibodies)/12 (TECTA (show TECTA Antibodies)), DFNA13 (COL11A2 (show COL11A2 Antibodies)), DFNA44 (CCDC50 (show CCDC50 Antibodies)), have been reported to date. [review]

  2. study identified EYA4 gene as targets for AML1 (show RUNX1 Antibodies)-ETO (show RUNX1T1 Antibodies) and indicated it as a novel tumor suppressor gene. In addition, we provided evidence that EYA4 gene might be a novel therapeutic target and a potential candidate for treating AML1 (show RUNX1 Antibodies)-ETO (show RUNX1T1 Antibodies)+ t (8;21) AML (show RUNX1 Antibodies).

  3. Loss of EYA4 expression is associated with intrahepatic cholangiocarcinoma.

  4. The identification of a novel EYA4 truncation mutation associated with DFNA10, rather than syndromic hearing loss, supports a previously reported genotype-phenotype correlation in this gene.

  5. results implicate Eya4/Six1 (show SIX1 Antibodies) regulates normal cardiac function via p27 (show PAK2 Antibodies)/casein kinase-2alpha/histone deacetylase 2 (show HDAC2 Antibodies) and indicate that mutations within this transcriptional complex and signaling cascade lead to the development of cardiomyopathy.

  6. In a Dutch family with c.464del EYA4 mutation, hearing impairment begins as a mid-frequency hearing impairment in childhood and develops into a high-frequency, moderate hearing impairment later in life.

  7. Genetic variations in the EYA4, GRHL2 (show GRHL2 Antibodies) and DFNA5 (show DFNA5 Antibodies) genes and their interactions with occupational noise exposure may play an important role in the incidence of noise-induced hearing loss (NIHL).

  8. analysis of an EYA4 mutation causing hearing loss in a Chinese DFNA family

  9. A novel missense mutation c.1643C>G (p.T548R) in EYA4 may cause autosomal dominant non-syndromic hearing impairment.

  10. EYA4 mutations are associated with autosomal dominant non-syndromic hearing loss.

EYA4 Antigen Profile

Antigen Summary

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant nonsyndromic sensorineural 10 locus. Defects in this gene are also associated with dilated cardiomyopathy 1J. Three transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with EYA4

  • eyes absent 4 homolog (Drosophila) (Eya4) antibody
  • eyes absent homolog 4 (Drosophila) (EYA4) antibody
  • eyes absent homolog 4 (Drosophila) (Eya4) antibody
  • B130023L16Rik antibody
  • CMD1J antibody
  • DFNA10 antibody

Protein level used designations for EYA4

eyes absent homolog 4 , dJ78N10.1 (eyes absent) , eyes absent 4

GENE ID SPECIES
14051 Mus musculus
2070 Homo sapiens
395716 Gallus gallus
483991 Canis lupus familiaris
100157256 Sus scrofa
538786 Bos taurus
292172 Rattus norvegicus
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