Browse our anti-COL4a5 (COL4a5) Antibodies

Full name:
anti-Collagen, Type IV, alpha 5 Antibodies (COL4a5)
On www.antibodies-online.com are 45 Collagen, Type IV, alpha 5 (COL4a5) Antibodies from 14 different suppliers available. Additionally we are shipping COL4a5 Proteins (2) and COL4a5 Kits (1) and many more products for this protein. A total of 52 COL4a5 products are currently listed.
Synonyms:
ASLN, ATS, CA54, col4a5, fj65e07, im:7157877, RGD1565499, si:ch211-174g17.1, wu:fj65e07
list all antibodies Gene Name GeneID UniProt
COL4a5 1287 P29400
COL4a5 12830  
COL4a5 363457  

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More Antibodies against COL4a5 Interaction Partners

Human Collagen, Type IV, alpha 5 (COL4a5) interaction partners

  1. Missense mutation in exon 28 of the COL4A5 gene is associated with focal segmental glomerulosclerosis.

  2. We show that collagen IV (show COL4 Antibodies) mutations, including COL4A5, frequently underlie FSGS (show ACTN4 Antibodies) and should be considered, particularly with a positive family history. Targeted NGS improves diagnostic efficiency by investigating many candidate genes in parallel.

  3. mutations in COL4A3 (show COL4a3 Antibodies), COL4A4 (show Col4a4 Antibodies), and COL4A5 in Chinese patients with Alport Syndrome

  4. Synonymous COL4A5 substitution responsible for X-linked Alport syndrome.

  5. Sanger sequencing of these regions identified a novel splicesite mutation in intron 9 (c.547-3C>A) of the COL4A5 gene. Subsequent cDNA analysis revealed that c.547- 3C>A led to skipping of exon 10, which resulted in an in-frame deletion of 21 amino acids from the a5 chain of type IV collagen (show COL4 Antibodies). This is the first report of the novel c.547-3C>A splicing mutation in the collagen domain of COL4A5 gene.

  6. Coinheritance of COL4A5 and MYO1E (show MYO1E Antibodies) mutations accentuate the severity of kidney disease.

  7. Case Report: subepidermal blistering disease with autoantibodies to multiple laminin subunits which developed autoantibodies to COL4A5 associated with membranous glomerulonephropathy.

  8. New COL4A5 mutations among Portuguese patients with collagen IV (show COL4 Antibodies)-related nephropathies were identified in unrelated individuals.

  9. alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor (show ITGA2 Antibodies) DDR1 (show DDR1 Antibodies)-mediated ERK (show EPHB2 Antibodies) activation.

  10. we identified seven families with associated mutations in COL4A3 (show COL4a3 Antibodies) and COL4A4 (show Col4a4 Antibodies) genes and four families with associated mutations in COL4A4 (show Col4a4 Antibodies) and COL4A5. We did not find kindreds with digenic inheritance attributable to mutations in COL4A3 (show COL4a3 Antibodies) and COL4A5

Mouse (Murine) Collagen, Type IV, alpha 5 (COL4a5) interaction partners

  1. Findings indicate a role for collagen alpha-5(IV) chain (Col4a5) in the regulation of macrophage responses to mycobacterial infection and identify Col4a5 as a potential target for the host-directed anti-mycobacterial therapy.

  2. alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor (show ITGA2 Antibodies) DDR1 (show DDR1 Antibodies)-mediated ERK (show EPHB2 Antibodies) activation.

  3. In murine embryos, collagen IV (show COL4 Antibodies) subunits alpha1(IV), alpha2(IV), alpha5(IV) and alpha6(IV) were detected in the basement membrane surrounding the lens vesicle, and they persisted in the capsule until adulthood.

  4. In kidney, when expressed onto Col4a3 (show COL4a3 Antibodies)(-/-) background, human alpha3(IV (show COL4a3 Antibodies)) chain restored expression of and co-assembled with mouse alpha4 and alpha5(IV) chains at sites where human alpha3(IV (show COL4a3 Antibodies)) was expressed. All three chains required for network assembly.

  5. Alpha3(IV (show COL4a3 Antibodies)), alpha4(IV), and alpha5(IV) chains form a complex, which is a heterotrimer, and a defect in complex formation might be one of the molecular mechanisms underlying the pathogenesis of Alport syndrome.

  6. the proximal bifunctional promoter regulates the expression of the alpha5(IV) and alpha6(IV) genes in a cell-specific manner and demonstrates promoter plasticity in growth factor regulation of type IV collagen (show COL4 Antibodies) genes in different tissues of the body.

COL4a5 Antigen Profile

Antigen Summary

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.

Alternative names and synonyms associated with COL4a5

  • collagen, type IV, alpha 5 (COL4A5) antibody
  • collagen, type IV, alpha 1 (col4a1) antibody
  • collagen, type IV, alpha 5 (LOC100285389) antibody
  • collagen, type IV, alpha 5 (Col4a5) antibody
  • ASLN antibody
  • ATS antibody
  • CA54 antibody
  • col4a5 antibody
  • fj65e07 antibody
  • im:7157877 antibody
  • RGD1565499 antibody
  • si:ch211-174g17.1 antibody
  • wu:fj65e07 antibody

Protein level used designations for COL4a5

collagen, type IV, alpha 5 , type IV collagen alpha 5-like , type IV collagen alpha 5 chain , collagen alpha-5(IV) chain-like , collagen IV, alpha-5 polypeptide , collagen alpha-5(IV) chain , collagen of basement membrane, alpha-5 chain , dA149D17.3 , dA24A23.1 , collagen type IV alpha5 chain , procollagen type IV alpha 5 , procollagen, type IV, alpha 5 , collagen, type IV, alpha 5 (Alport syndrome) , type IV collagen alpha 5

GENE ID SPECIES
511602 Bos taurus
554269 Danio rerio
703814 Macaca mulatta
100519180 Sus scrofa
465805 Pan troglodytes
100285389 Zea mays
1287 Homo sapiens
12830 Mus musculus
363457 Rattus norvegicus
403466 Canis lupus familiaris
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