Browse our anti-DVL1 (DVL1) Antibodies

Full name:
anti-Dishevelled Segment Polarity Protein 1 Antibodies (DVL1)
On www.antibodies-online.com are 6 Dishevelled Segment Polarity Protein 1 (DVL1) Antibodies from 4 different suppliers available. Additionally we are shipping DVL1 Proteins (4) and and many more products for this protein. A total of 14 DVL1 products are currently listed.
Synonyms:
DVL, DVL1L1, DVL1P1
list all antibodies Gene Name GeneID UniProt
DVL1 1855 O14640
DVL1    
DVL1    

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Human Dishevelled Segment Polarity Protein 1 (DVL1) interaction partners

  1. The DEP (show ZDHHC21 Antibodies) domain of Dishevelled (show DVL2 Antibodies) undergoes a conformational switch, from monomeric to swapped dimer, to trigger DIX domain-dependent polymerization and signaling to beta-catenin (show CTNNB1 Antibodies).

  2. two mutually exclusive functions of the DEP (show ZDHHC21 Antibodies) domain in Wnt (show WNT2 Antibodies) signal transduction - binding to Frizzled to recruit Dishevelled (show DVL2 Antibodies) to the receptor complex, is reported.

  3. we show that Wnt5a (show WNT5A Antibodies) rapidly represses rDNA gene transcription in breast cancer cells and generates a chromatin state with reduced transcription of rDNA by RNA polymerase I (show POLR1C Antibodies) (Pol I). These effects were specifically dependent on Dishevelled1 (DVL1), which accumulates in nucleolar organizer regions (NORs) and binds to rDNA regions of the chromosome.

  4. Data show that dishevelled (show DVL2 Antibodies) proteins DVL1, 2 and 3 were exclusively expressed in chronic lymphatic leukaemia (CLL) cells as compared to normal peripheral blood mononuclear cells (PBMCs).

  5. The secreted frizzled-related protein (show SFRP2 Antibodies) and disheveled protein family members appear to be actively involved in the pathogenesis of primary testicular germ cell tumors.

  6. Data show that receptor for activated C kinase 1 (RACK1 (show GNB2L1 Antibodies)) interacts with Dishevelled (Dvl (show DVL2 Antibodies)) proteins and promotes their lysosomal degradation, and this effect is enhanced by autophagy induction.

  7. TMEM88 stimulated triple negative breast cancer cell invasion by interacting with DVLl.

  8. Specific -1 frameshift variants in the penultimate exon of DVL1 cause autosomal-dominant Robinow syndrome.

  9. Results show that coexpression of IQGAP1 (show IQGAP1 Antibodies) and Dvl (show DVL2 Antibodies) in the cytoplasm and nucleus was correlated with the lymph nodal metastase and poor prognosis of non-small cell lung cancer.

  10. Data indicate Dishevelled (DVL (show DVL2 Antibodies)) as a dual function adaptor to recruit negative regulators ZNRF3 (show ZNRF3 Antibodies)/RNF43 (show RNF43 Antibodies) to Wnt (show WNT2 Antibodies) receptors to ensure proper control of pathway activity.

DVL1 Antigen Profile

Antigen Summary

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

Alternative names and synonyms associated with DVL1

  • dishevelled segment polarity protein 1 (DVL1) antibody
  • DVL antibody
  • DVL1L1 antibody
  • DVL1P1 antibody

Protein level used designations for DVL1

DSH homolog 1 , dishevelled 1 (homologous to Drosophila dsh) , dishevelled, dsh homolog 1 , dishevelled-1 , segment polarity protein dishevelled homolog DVL-1

GENE ID SPECIES
1855 Homo sapiens
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