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Human Polyclonal MINK1 Primary Antibody for IP, WB - ABIN439672
Gloerich, ten Klooster, Vliem, Koorman, Zwartkruis, Clevers, Bos: Rap2A links intestinal cell polarity to brush border formation. in Nature cell biology 2012
Show all 2 Pubmed References
MINK (show KCNE1 Antibodies) plays a functional role in the IRES-mediated translation of EV71 viral RNA and may provide a potential target for the development of specific antiviral strategies against EV71 infection
Misshapen-like kinase 1 (MINK1) is a novel component of striatin (show STRN Antibodies)-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis.
MINK1 interacts with and phosphorylates PRICKLE1 (show PRICKLE1 Antibodies) and PRICKLE2 (show PRICKLE2 Antibodies).
MINK (show KCNE1 Antibodies) interaction with Rap2 (show RAP2A Antibodies) plays a critical role in maintaining the morphological integrity of dendrites and synaptic transmission.
Analysis of the coding region of the NIK (show MAP3K14 Antibodies) gene in progressive supranuclear palsy (PSP (show MSMB Antibodies)) patients through single strand conformation polymorphism and direct sequencing does not support a pathogenic role of the NIK (show MAP3K14 Antibodies) gene in PSP (show MSMB Antibodies).
results suggest that human Misshapen/NIKs-related kinase beta (hMINK beta) plays an important role in cytoskeleton reorganization, cell adhesion, and cell motility(hMINKbeta)
using in vitro dephosphorylation assays, we demonstrate that Mastl (show MASTL Antibodies) promotes persistent MPS1 phosphorylation by inhibiting PP2A (show PPP2R2B Antibodies)/B55-mediated MPS1 dephosphorylation rather than affecting Cdk1 (show CDK1 Antibodies) kinase activity. Our findings establish a key regulatory function of the Greatwall (show MASTL Antibodies) kinase/Mastl (show MASTL Antibodies) - PP2A (show PPP2R2B Antibodies)/B55 pathway in preventing premature SAC (show ADCY10 Antibodies) silencing
MINK1 may be an important signaling molecule that mediates mitogen-activated protein kinase (show MAPK1 Antibodies) signaling and participates in platelet activation and thrombus formation.
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
misshapen-like kinase 1 (zebrafish)
, misshapen/NIK-related kinase
, GCK family kinase MINK
, MAPK/ERK kinase kinase kinase 6
, MEK kinase kinase 6
, MEKKK 6
, mitogen-activated protein kinase kinase kinase kinase 6
, serine/threonine protein kinase
, GCK family kinase MiNK
, GCK family kinase
, Misshapen/NIKs-related kinase
, Yeast Sps1/Ste20-related kinase 2
, misshapen-like kinase 1