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anti-Human Neuroligin 1 Antibodies:
anti-Mouse (Murine) Neuroligin 1 Antibodies:
anti-Rat (Rattus) Neuroligin 1 Antibodies:
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Mammalian Monoclonal Neuroligin 1 Primary Antibody for ISt, IHC - ABIN1304856
Zou, McSweeney, Sebastian, Reynolds, Dong, Zhou, Deng, Wang, Liu, Zhu, Zou, Shi, Albert, Mao: A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors. in Neural development 2015
Show all 8 Pubmed References
Cow (Bovine) Polyclonal Neuroligin 1 Primary Antibody for ELISA - ABIN250533
Chih, Engelman, Scheiffele: Control of excitatory and inhibitory synapse formation by neuroligins. in Science (New York, N.Y.) 2005
Human Monoclonal Neuroligin 1 Primary Antibody for ELISA, WB - ABIN393306
Bernard, Castano, Bayer, Benke: Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures. in Neuropharmacology 2014
Rat (Rattus) Polyclonal Neuroligin 1 Primary Antibody for WB - ABIN1742286
Dahlhaus, Hines, Eadie, Kannangara, Hines, Brown, Christie, El-Husseini: Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus. in Hippocampus 2010
Coinjection of low doses of morpholinos for beta-neurexin 1a and neuroligin 1 together or in combination with morpholinos targeting the -heparin--binding isoforms of vascular endothelial growth factor A (show VEGFA Antibodies) recapitulates the observed abnormalities
Findings support a contribution of the NLGN1 gene pathway to the neurobiological underpinnings of PTSD.
We show that a novel NLGN1 Pro89Leu (P89L) missense variant found in two autism spectrum disorder (ASD (show ARSD Antibodies)) siblings leads to changes in cellular localization, protein degradation, and to the impairment of spine formation. Furthermore, we generated the knock-in P89L mice, and we show that the P89L heterozygote mice display abnormal social behavior, a core feature of ASD (show ARSD Antibodies)
the expression of NL1 and its binding partner neurexin (show NRXN1 Antibodies)-1beta was increased in temporal lobe epileptic foci in patients and lithium-pilocarpine-treated epileptic rats.
Neuroligin 1 (NL1) promotes the formation of glutamatergic synapses and mediates long-term potentiation.
NLGN1 was associated with schizophrenia in Chinese Han Populations
Increasing expression of TGF-beta1 (show TGFB1 Antibodies) protein, decreasing expressions of Ghrelin (show GHRL Antibodies), Neurexin (show NRXN1 Antibodies), and Neuroligin proteins can induce the loss or dysfunction of ganglion cells in distal intestinal canal
Neuroligin-1 and Glu (show DCTN1 Antibodies) may represent new markers of ganglion cells, whose expression may correlate with the pathogenesis, diagnosis, differential diagnosis or classification of Hirschsprung's disease.
Results indicate that the neurexin (show NRXN1 Antibodies) and neuroligin synaptic complex is intrinsically involved in the regulation of DISC1 (show DISC1 Antibodies) function, thus contributing to a better understanding of the pathology of schizophrenia.
Monitoring the attachment and detachment of neurexin (Nrx (show NRXN1 Antibodies))-coated quantum dots measures the rates of neurexin (Nrx (show NRXN1 Antibodies))/neuroligin interaction in the hippocampus.
We identified a cluster of single nucleotide polymorphisms at the NLGN1 locus showing significant association with BP variability. Follow-up analyses did not support an association with risk of ischemic stroke and its subtypes
Co-expression of gamma-Pcdhs inhibits the ability of Nlg1 to increase spine density and to induce presynaptic differentiation in hippocampal neurons in vitro.
The alternatively spliced segment 4 (AS4) of NRX (show NXN Antibodies) genes (Nrxn) is a critical element in selective trans-synaptic interactions. This study evaluated the synaptogenic receptor activity of NL1 (show MMEL1 Antibodies)/2/3 isoforms in a neuron-fibroblast co-culture system, in which the Nrxn AS4 segments are manipulated using SLM2 (show KHDRBS3 Antibodies), a selective and dominant regulator of AS4 splicing.
We show that a novel NLGN1 Pro89Leu (P89L) missense variant found in two autism spectrum disorder (ASD (show GUSB Antibodies)) siblings leads to changes in cellular localization, protein degradation, and to the impairment of spine formation. Furthermore, we generated the knock-in P89L mice, and we show that the P89L heterozygote mice display abnormal social behavior, a core feature of ASD (show GUSB Antibodies)
The results indicate that Nrx2alpha and NL1 (show MMEL1 Antibodies) are targets of Abeta (show APP Antibodies) oligomers and that prevention of this interaction reduces the deleterious impact of Abeta (show APP Antibodies) oligomers on synapses and cognition.
Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization.
Study shows that astrocyte-secreted hevin is a trans-synaptic linker that bridges presynaptic NRX1alpha with postsynaptic NL1B. This way, hevin organizes both pre- and postsynaptic specializations and aligns them across the synapse.
Results are indicative of an altered immediate response of the brain to peripheral stimulation in Nlgn1 KO mice, and suggest a role for NLGN1 in the regulation of cerebrovascular responses
the R451C mutation in the Nlgn3 (show NLGN3 Antibodies) gene, associated with autism spectrum disorder in humans, confers resistance to induced seizures
This study provided first evidence that NL1 (show MMEL1 Antibodies) is essential for normal excitatory transmission and long-term synaptic plasticity in the hippocampus of intact animals.
NLGN1 and alpha6 integrin preferentially colocalize in the mature retinal vessels, whereas NLGN1 deletion causes an aberrant VE-cadherin (show CDH5 Antibodies), laminin and alpha6 integrin distribution in vessels
transmembrane ligand for neurexins\; involved in development and maturation of synaptic connections
, neuroligin I
, neuroligin 1 isoform A1A2B