Browse our anti-NMDAR2A (GRIN2A) Antibodies

Full name:
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a Antibodies (GRIN2A)
On www.antibodies-online.com are 238 Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies from 22 different suppliers available. Additionally we are shipping NMDAR2A Kits (28) and NMDAR2A Proteins (9) and many more products for this protein. A total of 280 NMDAR2A products are currently listed.
Synonyms:
EPND, GluN2A, GRIN2A, NMDAR2A, NR2A
list all antibodies Gene Name GeneID UniProt
GRIN2A 2903 Q12879
GRIN2A 24409 Q00959
GRIN2A 14811 P35436

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Most Popular Reactivities for anti-NMDAR2A (GRIN2A) Antibodies

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anti-Human NMDAR2A Antibodies:

anti-Rat (Rattus) NMDAR2A Antibodies:

anti-Mouse (Murine) NMDAR2A Antibodies:

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Top referenced anti-NMDAR2A Antibodies

  1. Human Polyclonal NMDAR2A Primary Antibody for EIA, FACS - ABIN953719 : Endele, Rosenberger, Geider, Popp, Tamer, Stefanova, Milh, Kortüm, Fritsch, Pientka, Hellenbroich, Kalscheuer, Kohlhase, Moog, Rappold, Rauch, Ropers, von Spiczak, Tönnies, Villeneuve, Villard, Zabel, Zenker, Laube, Reis, Wieczorek, Van Maldergem, Kutsche: Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes. in Nature genetics 2010 (PubMed)
    Show all 5 references for 953719

  2. Human Polyclonal NMDAR2A Primary Antibody for EIA, IHC (p) - ABIN953720 : King, Eugenin, Hazleton, Morgello, Berman: Mechanisms of HIV-tat-induced phosphorylation of N-methyl-D-aspartate receptor subunit 2A in human primary neurons: implications for neuroAIDS pathogenesis. in The American journal of pathology 2010 (PubMed)
    Show all 5 references for 953720

  3. Human Polyclonal NMDAR2A Primary Antibody for IF (p), IHC (p) - ABIN747353 : Zhao, Li, Wei, Savage, Zhou, Ma: Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring. in Neurobiology of disease 2014 (PubMed)
    Show all 2 references for 747353

  4. Mouse (Murine) Monoclonal NMDAR2A Primary Antibody for IF, WB - ABIN968802 : Ishii, Moriyoshi, Sugihara, Sakurada, Kadotani, Yokoi, Akazawa, Shigemoto, Mizuno, Masu: Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. in The Journal of biological chemistry 1993 (PubMed)
    Show all 2 references for 968802

  5. Human Monoclonal NMDAR2A Primary Antibody for ICC, IF - ABIN2483897 : Teng, Cai, Zhou, Zhang, Liu, Wang, Dai, Zhao, Sun: Evolutionary mode and functional divergence of vertebrate NMDA receptor subunit 2 genes. in PLoS ONE 2010 (PubMed)

  6. Cow (Bovine) Polyclonal NMDAR2A Primary Antibody for IHC, WB - ABIN2776120 : Kim, Chang, Nagpal, Yamashita, Baek, Dasgupta, Wu, Osada, Woo, Westra, Trink, Ratovitski, Moon, Sidransky: The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth. in Oncogene 2008 (PubMed)

  7. Rat (Rattus) NMDAR2A Primary Antibody for ELISA, WB - ABIN1742591 : Wang, Liu, Fu, Wang, Lu: Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors. in Nature neuroscience 2003 (PubMed)

More Antibodies against NMDAR2A Interaction Partners

Human Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) interaction partners

  1. 2-methoxyestradiol impacts on glycine/serine-mediated metabolic reprogramming in osteosarcoma cells by its interaction with GRIN1 (show GRIN1 Antibodies)/GluN2A receptors.

  2. a de novo missense mutation in the GRIN2A gene in a patient with childhood focal epilepsy and acquired epileptic aphasia. The mutant decreases NMDAR (show GRIN1 Antibodies) activation suggesting NMDAR (show GRIN1 Antibodies) hypofunction may contribute to the epilepsy pathogenesis.

  3. genetic association studies in population in China: Data suggest that one SNP in GRIN2A (rs2650429; but not rs6497540 or rs9302415) is associated with lead-induced neurotoxicity; in this case-control study, cases were lead-exposed workers from battery plants. Lead-exposed individuals have lower serum GRIN2A levels compared with controls; lead decreases GRIN2A expression levels in HEK293 cell.

  4. Two adjacent phenylalanines in the NMDA receptor GluN2A subunit M3 domain interactively regulate alcohol sensitivity and ion channel gating.

  5. The GRIN2A genotype was not associated with the rate of clinical progression of PD in the placebo group.

  6. most rare variants in GluN2A were associated with epilepsy, whereas GluN2B (show GRIN2B Antibodies) variants were associated with intellectual disability with or without seizures

  7. the gain-of-function M817V mutation causes overactivation of NMDAR (show GRIN1 Antibodies) and drives neuronal hyperexcitability.

  8. To determine genetic variability within the N-methyl-D-aspartate receptor 2A sub-unit (GRIN2A) gene promoter and its association with concussion recovery time.

  9. Knockdown of PKD1 (show PKD1 Antibodies) did not affect NMDAR (show GRIN1 Antibodies) internalization but prevented the phosphorylation and inhibition of remaining surface NMDARs and NMDAR (show GRIN1 Antibodies)-mediated synaptic functions.

  10. Findings suggest that mutations in GRIN2A preferentially are involved in genetic variance of pediatric idiopathic generalized epilepsy and do not contribute significantly to either adult focal epilepsies as temporal lobe epilepsy or generalized epilepsies

Mouse (Murine) Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) interaction partners

  1. This study demonstrated that Increasing the GluN2A/GluN2B (show GRIN2B Antibodies) Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

  2. Grin2aPKC mice exhibit reduced anxiety in the open field test, light dark emergence test, and elevated plus maze. Overall, these results suggest that at least one of those PKC (show PKC Antibodies)-mediated phosphorylation sites regulates NMDAR (show GRIN1 Antibodies)-mediated signaling that modulates anxiety.

  3. These data suggest that chronic early postnatal SSS influences spatial learning and memory ability, levels of hippocampal NR2B (show GRIN2B Antibodies), and NR2A/NR2B (show GRIN2B Antibodies) ratios in adult males.

  4. Rph3A (show RPH3A Antibodies) interacts with GluN2A and PSD-95 (show DLG4 Antibodies) forming a complex that regulates NMDARs stabilization at postsynaptic membranes.

  5. Egr-1 (show EGR1 Antibodies) is involved in NMDAR (show GRIN1 Antibodies)-mediated PSD-95 (show DLG4 Antibodies) down-regulation and AMPAR endocytosis, a process important in the expression of long term depression

  6. Study demonstrated that GluN2A carboxy-terminal domain is responsible for the impaired long-term olfactory and social memory observed in the GluN2A overexpression mice

  7. Results establish the GluN2A subunit as a significant contributor to both bidirectional synaptic plasticity and spatial pattern separation in the dentate gyrus

  8. Best1 (show BEST1 Antibodies)-mediated astrocytic glutamate (show GRIN1 Antibodies) activates the synaptic N-methyl-D-aspartate receptor (show GRIN1 Antibodies) (NMDAR (show GRIN1 Antibodies)) and modulates NMDAR (show GRIN1 Antibodies)-dependent synaptic plasticity.

  9. Data suggest a role for GluN2A in ethanol tolerance.

  10. We conclude that TSPYL2 (show TSPYL2 Antibodies) contributes to cognitive variability through regulating the expression of Grin2a and Grin2b (show GRIN2B Antibodies).

NMDAR2A (GRIN2A) Antigen Profile

Antigen Summary

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NMDAR2A (GRIN2A)

  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A) antibody
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A (grin2a) antibody
  • glutamate receptor ionotropic, NMDA 2A-like (LOC524212) antibody
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A (Grin2a) antibody
  • glutamate receptor, ionotropic, NMDA2A (epsilon 1) (Grin2a) antibody
  • EPND antibody
  • GluN2A antibody
  • GRIN2A antibody
  • NMDAR2A antibody
  • NR2A antibody

Protein level used designations for GRIN2A

N-methyl-D-aspartate receptor subunit NR2A , glutamate receptor, ionotropic, N-methyl D-aspartate 2A , glutamate [NMDA] receptor subunit epsilon-1-like , N-methyl D-aspartate receptor subtype 2A , N-methyl-D-aspartate receptor channel, subunit epsilon-1 , N-methyl-D-aspartate receptor subunit 2A , NMDA receptor subtype 2A , glutamate [NMDA] receptor subunit epsilon-1 , glutamate receptor ionotropic, NMDA 2A , hNR2A , glutamate [NMDA] receptor subunit epsilon 1 , glutamate receptor, ionotropic, N-methyl-D-aspartate subunit 2A , GluRepsilon1

GENE ID SPECIES
778440 Taeniopygia guttata
100127346 Xenopus laevis
100411569 Callithrix jacchus
100438553 Pongo abelii
100584731 Nomascus leucogenys
524212 Bos taurus
2903 Homo sapiens
24409 Rattus norvegicus
100727265 Cavia porcellus
490012 Canis lupus familiaris
427678 Gallus gallus
454396 Pan troglodytes
14811 Mus musculus
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