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anti-Human CARD11 antibody for Enzyme Immunoassay

Recommended CARD11 Antibody (supplied by: Log in to see )

Antigen
Caspase Recruitment Domain Family, Member 11 (CARD11) Antibodies
  • 0610008L17Rik
  • 2410011D02Rik
  • BENTA
  • BIMP3
  • CARD11
  • CARMA1
  • LOC100232755
  • PPBL
Reactivity
Human, Mouse (Murine)
70
30
4
4
4
1
1
Host
Rabbit
53
19
1
1
Clonality
Polyclonal
Conjugate
This CARD11 antibody is un-conjugated
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
67
40
36
16
7
6
4
3
1
1
Supplier
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Catalog No. ABIN499539
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008870071 ABIN614918 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal

Top referenced anti-CARD11 antibody for Enzyme Immunoassay

Similar anti-CARD11 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 16 Antibodies 35 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Immunochromatography (IC) 1 Antibodies 3 Antibodies
Immunocytochemistry (ICC) 4 Antibodies 7 Antibodies
Immunofluorescence (IF) 4 Antibodies 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 15 Antibodies 40 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies
Western Blotting (WB) 28 Antibodies

General

Antigen Caspase Recruitment Domain Family, Member 11 (CARD11) Antibodies
Reactivity Human, Mouse (Murine)
(70), (30), (4), (4), (4), (1), (1)
Host Rabbit
(53), (19), (1), (1)
Clonality
Polyclonal
Conjugate This CARD11 antibody is un-conjugated
(1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(67), (40), (36), (16), (7), (6), (4), (3), (1), (1)
Pubmed 4 references available
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Product Details anti-CARD11 Antibody

Target Details CARD11 Application Details Handling References for anti-CARD11 Antibody (ABIN499539) Images
Specificity CARMA1 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARMA1.
Purification Affinity chromatography purified via peptide column
Immunogen Human CARMA1 Peptide
Isotype IgG

Target Details CARD11

Product Details anti-CARD11 Antibody Application Details Handling References for anti-CARD11 Antibody (ABIN499539) Images back to top
Antigen
Alternative Name CARD11 / CARMA1 (CARD11 Antibody Abstract)
Background CARMA proteins belong to the membrane-associated guan-ylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules (1). CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types (2-4). Both CARMA1 and CARMA3 associate with NEMO, the regulatory subunit of the I?K complex, thereby regulating activation of the NF-kappaB transcription factor (5). Also, gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS, indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems (6).Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 11
Gene ID 84433
UniProt Q9BXL7
Research Area Apoptosis/Necrosis
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-CARD11 Antibody Target Details CARD11 Handling References for anti-CARD11 Antibody (ABIN499539) Images back to top
Application Notes ELISA. Western Blot: CARMA1 antibody can be used for detection of CARMA1 at 0.5 to 2 μg/mL. Aband at approximately 125 kDa can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CARD11 Antibody Target Details CARD11 Application Details References for anti-CARD11 Antibody (ABIN499539) Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-CARD11 Antibody (ABIN499539)

Product Details anti-CARD11 Antibody Target Details CARD11 Application Details Handling Images back to top
Background publications

McAllister-Lucas, Inohara, Lucas, Ruland, Benito, Li, Chen, Chen, Yamaoka, Verma, Mak, Núñez: "Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction." in: The Journal of biological chemistry, Vol. 276, Issue 33, pp. 30589-97, 2001

Gaide, Martinon, Micheau, Bonnet, Thome, Tschopp: "Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation." in: FEBS letters, Vol. 496, Issue 2-3, pp. 121-7, 2001

Bertin, Wang, Guo, Jacobson, Poyet, Srinivasula, Merriam, DiStefano, Alnemri: "CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B." in: The Journal of biological chemistry, Vol. 276, Issue 15, pp. 11877-82, 2001

Fanning, Anderson: "Protein modules as organizers of membrane structure." in: Current opinion in cell biology, Vol. 11, Issue 4, pp. 432-9, 1999

Images

Product Details anti-CARD11 Antibody Target Details CARD11 Application Details Handling References for anti-CARD11 Antibody (ABIN499539) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CARD11 antibody (Caspase Recruitment Domain Family, Member 11) (ABIN499539) Immunohistochemistry of CARMA1 in mouse thymus with CARMA1 antibody at 10 μg/ml.
Western Blotting (WB) image for anti-CARD11 antibody (Caspase Recruitment Domain Family, Member 11) (ABIN499539) Western blot analysis of CARMA1 expression in mouse thymus cell lysate with AP30186PU...