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CARD11 antibody (N-Term)
CARD11
Reactivity: Human, Mouse
WB, IHC, ICC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CARD11 Antibody
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Target
See all CARD11 Antibodies
CARD11
(Caspase Recruitment Domain Family, Member 11 (CARD11))
Binding Specificity
All epitopes for CARD11 antibodies
AA 1-221, N-Term
Reactivity
All reactivities for CARD11 antibodies
Human, Mouse
Host
All hosts for CARD11 antibodies
Rabbit
Clonality
All clonalities for CARD11 antibodies
Polyclonal
Conjugate
All conjugates for CARD11 antibodies
This CARD11 antibody is un-conjugated
Application
All applications for CARD11 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Specificity
Recognizes human and mouse CARMA1. Detects a band of ~130Dka by Western blot.
Cross-Reactivity
Human, Mouse (Murine)
Immunogen
N-terminal human CARMA1 (aa 1-221 containing the CARD domain).
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Discover our top product CARD11 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
Target Details for CARD11
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Target
CARD11
(Caspase Recruitment Domain Family, Member 11 (CARD11))
Alternative Name
CARMA1 (CARD11 Products )
Synonyms
BENTA antibody, BIMP3 antibody, CARMA1 antibody, PPBL antibody, 0610008L17Rik antibody, 2410011D02Rik antibody, CARD11 antibody, LOC100232755 antibody, caspase recruitment domain family member 11 antibody, caspase recruitment domain family, member 11 antibody, caspase recruitment domain-containing protein 11 antibody, CARD11 antibody, Card11 antibody, LOC100550812 antibody, card11 antibody
Background
CARMA1 is involved in the costimulatory signal essential for T cell receptor (TCR)-mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK.
UniProt
Q9BXL7
Pathways
TCR Signaling , Fc-epsilon Receptor Signaling Pathway , BCR Signaling
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