Browse our CCR5 Proteins (CCR5)

Full name:
C-C Chemokine Receptor Type 5 Proteins (CCR5)
On www.antibodies-online.com are 12 C-C Chemokine Receptor Type 5 (CCR5) Proteins from 6 different suppliers available. Additionally we are shipping CCR5 Antibodies (503) and CCR5 Kits (35) and many more products for this protein. A total of 561 CCR5 products are currently listed.
Synonyms:
AM4-7, CC-CKR-5, CCCKR5, CCR-5, CCR5, CD195, CKR-5, CKR5, CMKBR5, GPCR, IDDM22
list all proteins Gene Name GeneID UniProt
CCR5 12774 P51682
CCR5 117029 O08556
CCR5 1234 P51681

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CCR5 Proteins (CCR5) by Origin

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More Proteins for CCR5 Interaction Partners

Mouse (Murine) C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. The upregulation of CCR5 on the surface of the CD8 (show CD8A Proteins)(+) T cells increases the number of contacts with Ag-bearing dendritic cells, which ultimately results in increased CD8 (show CD8A Proteins)(+) T cell response to Ag rechallenge.

  2. CCL4-CCR5 axis can contribute to breast cancer metastasis to bone by mediating the interaction between cancer cells and fibroblasts in bone cavity.

  3. Cytokine-induced killer cells interact with tumor lysate-pulsed dendritic cells via CCR5 signaling.

  4. this study shows that diosgenin-mediated anti-allergic effects are associated with increased number of Foxp3+ Treg cells expressing CCR5

  5. CCR5 deficiency increased the production of TNF-alpha (show TNF Proteins) following LPS (show TLR4 Proteins) treatment through increased activation of the p38 (show CRK Proteins) pathway in the kidney, resulting in renal apoptosis and leukocyte infiltration and led to exacerbation of LPS (show TLR4 Proteins)-induced acute kidney injury.

  6. In West Nile virus infection of the central nervous system, CCR5 activity is required to limit viral burden in the cerebral cortex.

  7. CCR5 blockade suppresses B16 melanoma growth by inhibiting of IL-6 (show IL6 Proteins)-Stat3 (show STAT3 Proteins) signaling pathway via upregulation of SOCS3 (show SOCS3 Proteins).

  8. Data show that the activation of mammalian target of rapamycin (show FRAP1 Proteins) complex mTORC1 during encephalomyocarditis virus infection is chemokine (C-C) receptor 5-dependent and promotes the translation of inducible NO synthase (iNOS (show NOS2 Proteins)) and cyclooxygenase (COX)-2.

  9. CCL5-induced endothelial progenitor cell migration was increased by overexpression of CCR5 and that increase was abolished by addition of CCL5 antibody, suggesting CCL5/CCR5 interaction is involved in chemotactic effects of endothelial progenitor cells.

  10. These findings show that migration and activation of immune cells via CCR5 is required for controlling N. caninum parasites during the early phase of the infection.

Cow (Bovine) C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CCR5 expression.

Rhesus Monkey C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. CCR5 inhibition may provide a cardioprotective benefit in SIV infection by preventing cardiomyocyte CCR5 signaling.

  2. A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251.

  3. CCR5 downregulation on CD4(+) T cells by TCR activation has no measurable effect on susceptibility to SAIDS.

  4. CD4 and CD8 T cells are more vulnerable to SIV infection, indicating the the ability to express CCR5 may activate and hassten T cell death by SIV infection in vitro.

  5. Results estimate the infectivity of CCR5-tropic simian immunodeficiency virus SIV(mac251) in the gut (show GUSB Proteins).

  6. observed a significantly higher loss of CCR5(+) CD45RA(-) CD4 (show CD4 Proteins)(+) T cells in CD8 (show CD8A Proteins)(+) lymphocyte-depleted macaques than in controls

  7. Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 and CXCR4 (show CXCR4 Proteins) for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 (show CXCR4 Proteins) almost exclusively

Human C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. study revealed that while HIV-1 gp120 and Staph aureus LukED both target CCR5, they bind to different regions of the receptor, highlighting the divergence of the pathogens

  2. Genetic variation of CCR5 gene demonstrates a possible association with hypertension, diabetes mellitus and atherosclerosis comorbidity in patient treated with hemodialysis.

  3. Findings indicate the importance of chemokine (CC motif) ligand 5 (CCL5) genetic variability and CCL5-CCR5 (CC chemokine receptor 5) axis on the susceptibility to HCV.

  4. The transferred nuclear Overhauser effect (TRNOE) crosspeaks in the ternary complex were assigned to the specific Tyr protons in the human C-C chemokine receptor 5 (CCR5) chemokine receptor peptide and to methyl protons, predominantly of isoleucine residues, and also of leucine and/or valine residues of HIV-1 gp120 envelope protein.

  5. Intermolecular interactions of RANTES with its receptor CCR5 have been reported based on NMR spectroscopy measurements.

  6. Binding of J113863 to CCR2 or CCR5 also induced the recruitment of beta-arrestin 2, whereas UCB35625 did not. UCB35625 induced the chemotaxis of L1.2 cells expressing CCR2 or CCR5. In contrast, J113863 induced the migration of L1.2-CCR2 cells but antagonized the chemokine-induced migration of L1.2-CCR5 cells.

  7. The higher frequency of CCR5 wild-type allele among leishmaniasis patients may suggest an increased risk of HIV infection and also support its facilitative role in Leishmania infection

  8. CCR5 is reduced following low-intensity strength exercise with blood flow restriction.

  9. Mouse leukemia cell lines that could express hCD4 and CCR5 were thus established to facilitate normal entry of HIV-1 so that a human CD4/CCR5 transgenic mice cell model can be used to investigate the transmission and pathogenesis of HIV/AIDS and potential antiviral drugs against this disease.

  10. Macrophages promote glioblastoma cell invasion by the CCL4-CCR5 axis, and hypoxia enhances the interaction between these two types of cells by upregulating both CCL4 and CCR5 expression, respectively.

CCR5 Protein Profile

Protein Summary

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with CCR5

  • chemokine (C-C motif) receptor 5 (Ccr5)
  • chemokine (C-C motif) receptor 5 (CCR5)
  • chemokine (C-C motif) receptor 5 (gene/pseudogene) (CCR5)
  • AM4-7 protein
  • CC-CKR-5 protein
  • CCCKR5 protein
  • CCR-5 protein
  • CCR5 protein
  • CD195 protein
  • CKR-5 protein
  • CKR5 protein
  • CMKBR5 protein
  • GPCR protein
  • IDDM22 protein

Protein level used designations for CCR5

C-C CKR-5 , C-C chemokine receptor type 5 , CC-CKR-5 , CCR-5 , MIP-1 alpha receptor , chemokine (C-C) receptor 5 , C-C chemokine receptor 5 , CC chemokine receptor 5 , chemokine C-C motif receptor 5 , chemokine (C-C motif) receptor 5 , C-C motif chemokine receptor 5 A159A , HIV-1 fusion coreceptor , chemokine receptor CCR5 , chemr13

GENE ID SPECIES
12774 Mus musculus
117029 Rattus norvegicus
100101579 Oryctolagus cuniculus
484789 Canis lupus familiaris
497017 Bos taurus
735311 Macaca mulatta
100126710 Papio anubis
450128 Pan troglodytes
100190809 Pongo abelii
1234 Homo sapiens
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