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Browse our CCR5 Proteins (CCR5)

Full name:
C-C Chemokine Receptor Type 5 Proteins (CCR5)
On www.antibodies-online.com are 9 C-C Chemokine Receptor Type 5 (CCR5) Proteins from 6 different suppliers available. Additionally we are shipping CCR5 Antibodies (466) and CCR5 Kits (39) and many more products for this protein. A total of 525 CCR5 products are currently listed.
Synonyms:
AM4-7, CC-CKR-5, CCCKR5, CCR-5, CCR5, CD195, CKR-5, CKR5, CMKBR5, GPCR, IDDM22
list all proteins Gene Name GeneID UniProt
CCR5 12774 P51682
CCR5 117029 O08556
CCR5 1234 P51681

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CCR5 Proteins (CCR5) by Origin

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More Proteins for CCR5 Interaction Partners

Mouse (Murine) C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. In West Nile virus infection of the central nervous system, CCR5 activity is required to limit viral burden in the cerebral cortex.

  2. CCR5 blockade suppresses B16 melanoma growth by inhibiting of IL-6 (show IL6 Proteins)-Stat3 (show STAT3 Proteins) signaling pathway via upregulation of SOCS3 (show SOCS3 Proteins).

  3. Data show that the activation of mammalian target of rapamycin (show FRAP1 Proteins) complex mTORC1 during encephalomyocarditis virus infection is chemokine (C-C) receptor 5-dependent and promotes the translation of inducible NO synthase (iNOS (show NOS2 Proteins)) and cyclooxygenase (COX)-2.

  4. CCL5-induced endothelial progenitor cell migration was increased by overexpression of CCR5 and that increase was abolished by addition of CCL5 antibody, suggesting CCL5/CCR5 interaction is involved in chemotactic effects of endothelial progenitor cells.

  5. These findings show that migration and activation of immune cells via CCR5 is required for controlling N. caninum parasites during the early phase of the infection.

  6. our results suggest that the detrimental effects of C5a in this model are partly mediated through CCR5 activation downstream of C5aR1 (show C5AR1 Proteins), which may be evaluated for potential therapeutic exploitation in ALI/ARDS.

  7. CCR5 blockade promotes M2 macrophage activation and improves locomotor activity after spinal cord injury in mice.

  8. CCR5 KO mice show less cartilage degeneration but no change in bone or synovial response to medial meniscal destabilization.

  9. Results indicate that CCR5 deficiency modifies the nigrostriatal dopaminergic neuronal system and bidirectional interaction between neurons and glial cells via CCR5 might be important for dopaminergic neuronal survival

  10. These data bring new insights on the association between viral infections and the chemokine receptor CCR5.

Cow (Bovine) C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CCR5 expression.

Rhesus Monkey C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. CCR5 inhibition may provide a cardioprotective benefit in SIV infection by preventing cardiomyocyte CCR5 signaling.

  2. A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251.

  3. CCR5 downregulation on CD4(+) T cells by TCR activation has no measurable effect on susceptibility to SAIDS.

  4. CD4 and CD8 T cells are more vulnerable to SIV infection, indicating the the ability to express CCR5 may activate and hassten T cell death by SIV infection in vitro.

  5. Results estimate the infectivity of CCR5-tropic simian immunodeficiency virus SIV(mac251) in the gut (show GUSB Proteins).

  6. observed a significantly higher loss of CCR5(+) CD45RA(-) CD4 (show CD4 Proteins)(+) T cells in CD8 (show CD8A Proteins)(+) lymphocyte-depleted macaques than in controls

  7. Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 and CXCR4 (show CXCR4 Proteins) for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 (show CXCR4 Proteins) almost exclusively

Human C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. The authors provide the first evidence that shows CCR5 interaction with a dual-tropic HIV-1 Env (show ERVW-1 Proteins) played a significant role in Env (show ERVW-1 Proteins)-induced depletion of CD4 (show CD4 Proteins) T cells.

  2. Data indicate that on addition of the heat-shock proteins GroEL-GroES molecular chaperone system, the folding of the nascent chemokine receptor type 5 (CCR5) was significantly enhanced.

  3. The results of this study infer CCR5 and CCL5 (show CCL5 Proteins) participate in the response to tick-borne encephalitis virus, as well as to other neurotropic pathogens.

  4. Enhanced susceptibility of activated endocervical CD4+ T cells to HIV may be related to increased CCR5 expression by these cell subsets, but did not appear to be due to direct interaction of integrins a4b7 or a4b1 with HIV envelope.

  5. individuals carrying heterozygous or homozygous genotypes (GA+AA) for CCR2-64I polymorphisms seem to be at lower risk for cervical lesion [odds ratio (OR) = 0.37, p = 0.0008)]. The same was observed for the A allele (OR = 0.39, p = 0.0002), while no association was detected (p > 0.05) with CCR5-Delta32 polymorphism.

  6. The residues on the N-loop and beta-sheets of MIP-1a are close to both CCR1 and CCR5, and those in the C-terminal helix region are close to CCR5.

  7. Study provides the evidence that the chemokine receptor CCR5 is highly expressed and associated with poor prognosis in human glioblastoma. Mechanistically, CCL5 (show CCL5 Proteins)-CCR5 mediates activation of Akt (show AKT1 Proteins), and subsequently induces proliferation and invasive responses in U87 and U251 cells.

  8. CCR5-Delta32 polymorphism is associated with susceptibility to cancer.

  9. The relationship between CCR5 variation, HIV-1 reservoir size, lymphocyte activation, and CCR (show POR Proteins)% expression in patients receiving ant-HIV therapy is reported.

  10. the CCR5Delta32 polymorphism does not seem to influence the different clinical manifestations of Chagas disease but there is involvement of the CCR5 59029 A/G polymorphism in susceptibility to the different forms of chronic Chagas disease.

CCR5 Protein Profile

Protein Summary

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with CCR5

  • chemokine (C-C motif) receptor 5 (Ccr5)
  • chemokine (C-C motif) receptor 5 (CCR5)
  • chemokine (C-C motif) receptor 5 (gene/pseudogene) (CCR5)
  • AM4-7 protein
  • CC-CKR-5 protein
  • CCCKR5 protein
  • CCR-5 protein
  • CCR5 protein
  • CD195 protein
  • CKR-5 protein
  • CKR5 protein
  • CMKBR5 protein
  • GPCR protein
  • IDDM22 protein

Protein level used designations for CCR5

C-C CKR-5 , C-C chemokine receptor type 5 , CC-CKR-5 , CCR-5 , MIP-1 alpha receptor , chemokine (C-C) receptor 5 , C-C chemokine receptor 5 , CC chemokine receptor 5 , chemokine C-C motif receptor 5 , chemokine (C-C motif) receptor 5 , C-C motif chemokine receptor 5 A159A , HIV-1 fusion coreceptor , chemokine receptor CCR5 , chemr13

GENE ID SPECIES
12774 Mus musculus
117029 Rattus norvegicus
100101579 Oryctolagus cuniculus
484789 Canis lupus familiaris
497017 Bos taurus
735311 Macaca mulatta
100126710 Papio anubis
450128 Pan troglodytes
100190809 Pongo abelii
1234 Homo sapiens
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