anti-Human CD4 antibody for ELISA (Capture)

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • L3T4
  • Ly-4
  • CD4mut
  • W3/25
  • p55
  • CD4 molecule
  • CD4 antigen
  • T-cell surface glycoprotein CD4
  • Cd4 molecule
  • CD4
  • cd4
  • Cd4
Reactivity
Human
1250
656
235
78
68
41
36
28
27
26
22
21
19
16
15
15
13
10
10
9
7
6
5
5
5
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
Host
Mouse
1421
611
283
16
6
1
1
1
Clonality
Monoclonal
Conjugate
This CD4 antibody is conjugated to Alexa Fluor 488
264
232
170
108
54
54
53
48
36
34
34
33
30
26
22
21
21
20
19
19
18
18
18
18
16
15
15
13
13
9
9
8
8
6
5
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA (Capture)
1823
495
453
353
323
311
161
156
98
78
41
39
38
30
30
25
18
14
14
11
9
9
6
6
5
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
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Catalog No. ABIN2657417
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General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Human
(1250), (656), (235), (78), (68), (41), (36), (28), (27), (26), (22), (21), (19), (16), (15), (15), (13), (10), (10), (9), (7), (6), (5), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(1421), (611), (283), (16), (6), (1), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD4 antibody is conjugated to Alexa Fluor 488
(264), (232), (170), (108), (54), (54), (53), (48), (36), (34), (34), (33), (30), (26), (22), (21), (21), (20), (19), (19), (18), (18), (18), (18), (16), (15), (15), (13), (13), (9), (9), (8), (8), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA (Capture)
(1823), (495), (453), (353), (323), (311), (161), (156), (98), (78), (41), (39), (38), (30), (30), (25), (18), (14), (14), (11), (9), (9), (6), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling References for anti-CD4 antibody (ABIN2657417) Images
Purification The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
Clone SK3
Isotype IgG1 kappa

Target Details CD4

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Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling References for anti-CD4 antibody (ABIN2657417) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details References for anti-CD4 antibody (ABIN2657417) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C

References for anti-CD4 antibody (ABIN2657417)

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling Images back to top
Background publications

Arnó, Ruiz, Juan, Jou, Balagué, Zayat, Marfil, Martínez-Picado, Martínez, Romeu, Pujol-Borrell, Lane, Clotet: "Efficacy of low-dose subcutaneous interleukin-2 to treat advanced human immunodeficiency virus type 1 in persons with in: The Journal of infectious diseases, Vol. 180, Issue 1, pp. 56-60, 1999

Center, Kornfeld, Cruikshank: "Interleukin 16 and its function as a CD4 ligand." in: Immunology today, Vol. 17, Issue 10, pp. 476-81, 1997

Gaubin, Autiero, Houlgatte, Basmaciogullari, Auffray, Piatier-Tonneau: "Molecular basis of T lymphocyte CD4 antigen functions." in: European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, Vol. 34, Issue 9, pp. 723-8, 1997

Muench, Roncarolo, Namikawa: "Phenotypic and functional evidence for the expression of CD4 by hematopoietic stem cells isolated from human fetal liver." in: Blood, Vol. 89, Issue 4, pp. 1364-75, 1997

Evans, Wall, Platsoucas, Siegal, Fikrig, Testa, Good: "Thymus-dependent membrane antigens in man: inhibition of cell-mediated lympholysis by monoclonal antibodies to TH2 antigen." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, Issue 1, pp. 544-8, 1981

Images

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Supplier Images
Flow Cytometry (FACS) image for anti-CD4 Molecule (CD4) antibody (Alexa Fluor 488) (ABIN2657417) anti-CD4 Molecule (CD4) antibody (Alexa Fluor 488)