Browse our anti-CD45 (PTPRC) Antibodies

Full name:
anti-Protein tyrosine Phosphatase, Receptor Type, C Antibodies (PTPRC)
On www.antibodies-online.com are 2507 Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) Antibodies from 39 different suppliers available. Additionally we are shipping CD45 Proteins (33) and CD45 Kits (18) and many more products for this protein. A total of 2567 CD45 products are currently listed.
Synonyms:
B220, cd45, CD45R, GP180, L-CA, Lca, loc, Ly-5, LY5, Lyt-4, PTPRC, RT7, si:dkeyp-47c5.1, T200
list all antibodies Gene Name GeneID UniProt
PTPRC 5788 P08575
PTPRC 19264  
Anti-Rat PTPRC PTPRC 24699 P04157

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All available anti-CD45 Antibodies

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Top referenced anti-CD45 Antibodies

  1. Cat (Feline) Monoclonal CD45 Primary Antibody for FACS, IHC (fro) - ABIN118214 : Ballas, Rasmussen: Lymphokine-activated killer (LAK) cells. IV. Characterization of murine LAK effector subpopulations. in Journal of immunology (Baltimore, Md. : 1950) 1990 (PubMed)
    Show all 16 references for 118214

  2. Dog (Canine) Monoclonal CD45 Primary Antibody for FACS, IHC (fro) - ABIN118681 : Beverley, Merkenschlager, Terry: Phenotypic diversity of the CD45 antigen and its relationship to function. in Immunology. Supplement 1988 (PubMed)
    Show all 10 references for 118681

  3. Rat (Rattus) Monoclonal CD45 Primary Antibody for FACS, IHC (fro) - ABIN114375 : Brouard, Vanhove, Gagne, Neumann, Douillard, Moreau, Cuturi, Soulillou: T cell repertoire alterations of vascularized xenografts. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 5 references for 114375

  4. Human Polyclonal CD45 Primary Antibody for EIA, FACS - ABIN357138 : Stanton, Boxall, Hirai, Dawes, Tonks, Yasui, Kanaoka, Yuldasheva, Ishiko, Bodmer, Beverley, Tchilian: A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 5 references for 357138

  5. Rat (Rattus) Monoclonal CD45 Primary Antibody for FACS - ABIN114377 : Brown, Williams: Lymphocyte cell surface glycoproteins which bind to soybean and peanut lectins. in Immunology 1982 (PubMed)
    Show all 5 references for 114377

  6. Rat (Rattus) Monoclonal CD45 Primary Antibody for FACS - ABIN120474 : Butcher: A list of monoclonal antibodies specific for alloantigens of the rat. in Journal of immunogenetics 1988 (PubMed)
    Show all 3 references for 120474

  7. Mouse (Murine) Monoclonal CD45 Primary Antibody for FACS - ABIN114218 : Bottomly, Luqman, Greenbaum, Carding, West, Pasqualini, Murphy: A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines. in European journal of immunology 1989 (PubMed)
    Show all 2 references for 114218

  8. Mouse (Murine) Monoclonal CD45 Primary Antibody for FACS, IHC (fro) - ABIN114222 : Hathcock, Hirano, Hodes: CD45 expression by murine B cells and T cells: alteration of CD45 isoforms in subpopulations of activated B cells. in Immunologic research 1993 (PubMed)
    Show all 2 references for 114222

  9. Human Monoclonal CD45 Primary Antibody for FACS - ABIN1106398 : Lee, Huang, Chiang, Chiou, Chen, Hsieh, Jiang: Multipotential mesenchymal stem cells from femoral bone marrow near the site of osteonecrosis. in Stem cells (Dayton, Ohio) 2003 (PubMed)

More Antibodies against CD45 Interaction Partners

Human Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) interaction partners

  1. A phosphosite within the SH2 Domain of Lck regulates its activation by CD45. A negative feedback loop that responds to signaling events tunes active Lck amounts and TCR sensitivity.

  2. Our findings suggest that CD45 is a key regulator of BCR (show BCR Antibodies)-signaling thresholds mediated by T-cell help

  3. we demonstrate for the first time the physiological existence of ct-CD45 in human plasma and show that it may be an extrinsic factor contributing to the maintenance of human T-cell quiescence.

  4. Our findings suggest that if w/h ratio on SSC (show CYP11A1 Antibodies) versus CD45 plot is less than 1.6, AML (show RUNX1 Antibodies) may be considered, and if it is more than 1.6, ALL may be diagnosed. Using morphometric analysis of the blast cluster on SSC (show CYP11A1 Antibodies) versus CD45, it was possible to distinguish between ALL and AML (show RUNX1 Antibodies), and their subtypes.

  5. Use of the common leukocyte marker CD45 increases the sensitivity of the diagnosis of lymphocytic myocarditis.

  6. Review/Meta-analysis: Rheumatoid arthritis patients with PTPRC rs10919563 A allele show a poor response to anti-TNF (show TNF Antibodies) therapy.

  7. Data suggest that CD41 and CD45 expression marked the onset of haemangioblastoma (HB) neovascularisation and the stepwise development of the angioformative period, and also the underlying therapeutic targets of anti-vascular treatment.

  8. PTPRC has become the most replicated genetic biomarker of response to TNF (show TNF Antibodies) inhibitors

  9. CD45RO+ memory T-cells produce IL-17 (show IL17A Antibodies) in patients with atherosclerosis.

  10. Data show the structural basis for, and the potent signaling effects of, local CD45 antigen and kinase segregation.

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) interaction partners

  1. A phosphosite within the SH2 Domain of Lck regulates its activation by CD45. A negative feedback loop that responds to signaling events tunes active Lck amounts and TCR sensitivity.

  2. T cell receptor / TLR2 (show TLR2 Antibodies) co-stimulation expands CD25 (show IL2RA Antibodies)+CD45Rbhi T cells.

  3. Both the number of lung CD31 (show PECAM1 Antibodies)-CD45-Sca-1 (show Ly6a Antibodies)+ cells and the expression levels of the Shh (show SHH Antibodies) signaling pathway were downregulated in the lung tissues of mice with pulmonary emphysema. These cells and Shh (show SHH Antibodies) signaling pathway are reactivated during acute adenovirus infection.

  4. the transient upregulation of IL-1beta (show IL1B Antibodies) and PTPRC/CD45 during the early phase as well as the increased expression of collagen type I at later stages of repair and validate the differential expression of miR (show MLXIP Antibodies)-204, miR (show MLXIP Antibodies)-205, and miR (show MLXIP Antibodies)-31 in skin wounds.

  5. Increased numbers of CD4 (show CD4 Antibodies)(+)CD45RA(-)FoxP3 (show FOXP3 Antibodies)(low) cells may cause an imbalance between Treg and Th17 cells that is mainly localized to the colon.

  6. Use of the common leukocyte marker CD45 increases the sensitivity of the diagnosis of lymphocytic myocarditis.

  7. Aging induces loss of stemness with concomitant gain of myogenic properties of a pure population of CD34 (show CD34 Antibodies)+/CD45- muscle derived stem cells.

  8. deletion of Pten (show PTEN Antibodies) in CD45-expressing cells induces development of T-cell acute lymphoblastic leukemia and lymphoma, but not other hematologic malignancies

  9. A noncatalytic role for CD45 in regulating tonic, but not antigen-mediated, B-cell antigen receptor (BCR (show BCR Antibodies)) signaling through modulation of the function of the inhibitory coreceptor CD22 (show CD22 Antibodies), was identified.

  10. CD45 ligation specifically reduced Treg motility in an integrin-dependent manner, resulting in enhanced interactions between Tregs and DCs in vivo.

CD45 (PTPRC) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.

Alternative names and synonyms associated with CD45 (PTPRC)

  • protein tyrosine phosphatase, receptor type, C (PTPRC) antibody
  • protein tyrosine phosphatase, receptor type, C (ptprc) antibody
  • protein tyrosine phosphatase, receptor type, C (Ptprc) antibody
  • B220 antibody
  • cd45 antibody
  • CD45R antibody
  • GP180 antibody
  • L-CA antibody
  • Lca antibody
  • loc antibody
  • Ly-5 antibody
  • LY5 antibody
  • Lyt-4 antibody
  • PTPRC antibody
  • RT7 antibody
  • si:dkeyp-47c5.1 antibody
  • T200 antibody

Protein level used designations for PTPRC

receptor-type tyrosine-protein phosphatase C , leukocyte common antigen, CD45 , protein tyrosine phosphatase, receptor type, C , CD45 antigen , leukocyte common antigen , receptor-type tyrosine-protein phosphatase C-like , T200 glycoprotein , T200 leukocyte common antigen , protein tyrosine phosphatase, receptor type, c polypeptide , lymphocyte antigen 5 , lymphocyte common antigen , Protein tyrosine phosphatase, receptor-type, c polypeptide , leucocyte common antigen , leukocyte common antigen A , leukocyte common antigen B , membrane tyrosine phosphatase

GENE ID SPECIES
386580 Gallus gallus
457607 Pan troglodytes
490255 Canis lupus familiaris
559154 Danio rerio
100026890 Monodelphis domestica
100061950 Equus caballus
100074271 Ornithorhynchus anatinus
100358807 Oryctolagus cuniculus
100446144 Pongo abelii
100474611 Ailuropoda melanoleuca
100522631 Sus scrofa
100546661 Meleagris gallopavo
5788 Homo sapiens
19264 Mus musculus
24699 Rattus norvegicus
407152 Bos taurus
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