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|Application / Reactivity||Rat (Rattus)|
|Blocking Reagent (BR)||1 Antibodies|
|Dot Blot (DB)||1 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies|
|Flow Cytometry (FACS)||30 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Immunofluorescence (IF)||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||5 Antibodies|
|Immunohistochemistry (Acetone-fixed) (IHC (af))||3 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||3 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||3 Antibodies|
|Immunoprecipitation (IP)||8 Antibodies|
|Western Blotting (WB)||10 Antibodies|
|Reactivity||Rat (Rattus) Alternatives|
|Conjugate||This CD80 antibody is un-conjugated Alternatives|
Immunohistochemistry (Acetone-fixed) (IHC (af)), Flow Cytometry (FACS), Immunoprecipitation (IP)
|Supplier||Log in to see|
Product Details anti-CD80 AntibodyTarget Details CD80 Application Details Handling Images
Mouse anti Rat CD80, clone 3H5 specifically recognizes rat CD80, otherwise known as B7-1, a type I transmembrane glycoprotein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells.
CD80 is a B cell activation antigen, which functions in the CD28-CD80/CD86 co-stimulatory pathway vital for T cell activation and proliferation. In contrast, the interaction of CD80 with CD152 has an inhibitory effect on T cell responses.
Clone 3H5 has been shown to block the co-stimulatory activity of rat CD80.
Mouse Anti Rat Cd80
Protein Size: 321
|Immunogen||The immunogen for anti-Cd80 antibody: hTLV-1 transformed Lewis-S1 cells|
Target Details CD80Product Details anti-CD80 Antibody Application Details Handling Images back to top
|Alternative Name||Cd80 (CD80 Antibody Abstract)|
|Background||Mouse Anti Rat Cd80|
|Pathways||TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway|
Application DetailsProduct Details anti-CD80 Antibody Target Details CD80 Handling Images back to top
|Application Notes||Flow Cytometry: Use 10 μL of the suggested working dilution to label 1 x106 cells in 100 μL.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD80 Antibody Target Details CD80 Application Details Images back to top
|Handling Advice||Avoid repeated freezing and thawing as this may denature the antibody|
|Storage||4 °C,-20 °C|
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
ImagesProduct Details anti-CD80 Antibody Target Details CD80 Application Details Handling back to top