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|Application / Reactivity||Human|
|Dot Blot (DB)||1 Antibodies|
|Enzyme Immunoassay (EIA)||3 Antibodies|
|Flow Cytometry (FACS)||6 Antibodies|
|Immunocytochemistry (ICC)||4 Antibodies|
|Immunofluorescence (IF)||4 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||2 Antibodies|
|Immunohistochemistry (IHC)||5 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||6 Antibodies|
|Immunoprecipitation (IP)||7 Antibodies|
|Western Blotting (WB)||88 Antibodies|
|Antigen||IL2-Inducible T-Cell Kinase (ITK) Antibodies|
|Conjugate||This ITK antibody is un-conjugated Alternatives|
Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-ITK AntibodyTarget Details ITK Application Details Handling References for anti-ITK Antibody (ABIN969222) Images
|Immunogen||Purified recombinant fragment of human ITK expressed in E. coli.|
Target Details ITKProduct Details anti-ITK Antibody Application Details Handling References for anti-ITK Antibody (ABIN969222) Images back to top
|Alternative Name||ITK (ITK Antibody Abstract)|
|Background||This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.|
|Molecular Weight||72 kDa|
|Research Area||Signaling, Tyrosine Kinases|
|Pathways||TCR Signaling, Fc-epsilon Receptor Signaling Pathway|
Application DetailsProduct Details anti-ITK Antibody Target Details ITK Handling References for anti-ITK Antibody (ABIN969222) Images back to top
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
|Restrictions||For Research Use only|
HandlingProduct Details anti-ITK Antibody Target Details ITK Application Details References for anti-ITK Antibody (ABIN969222) Images back to top
|Buffer||Ascitic fluid containing 0.03 % sodium azide.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store at 4 °C or at -20 °C for long term.|
References for anti-ITK Antibody (ABIN969222)Product Details anti-ITK Antibody Target Details ITK Application Details Handling Images back to top
|Product cited in:||
Kogina, Shoda, Yamaguchi et al.: "Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4(+) T cells." in: Molecules and cells, Vol. 28, Issue 2, pp. 125-30, 2009 (PubMed).
Huck, Feyen, Niehues et al.: "Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation." in: The Journal of clinical investigation, Vol. 119, Issue 5, pp. 1350-8, 2009 (PubMed).
ImagesProduct Details anti-ITK Antibody Target Details ITK Application Details Handling References for anti-ITK Antibody (ABIN969222) back to top