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anti-Rat (Rattus) LAT antibody for Enzyme Immunoassay

Recommended LAT Antibody (supplied by: Log in to see )

Antigen
Linker For Activation of T Cells (LAT) Antibodies
  • LAT
  • lat
  • LAT1
  • pp36
  • linker for activation of T cells
  • LAT
  • lat
  • Lat
Epitope
C-Term
24
19
19
17
11
10
9
8
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
242
122
106
3
2
2
1
1
Host
Goat
142
109
12
2
Clonality
Polyclonal
Conjugate
This LAT antibody is un-conjugated
9
9
8
8
8
6
5
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
189
68
51
47
39
39
21
21
14
6
2
2
1
1
1
1
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Catalog No. ABIN374446
$ 379.50
Plus shipping costs $45.00

Top referenced anti-LAT antibody for Enzyme Immunoassay

Similar anti-LAT Antibodies

Application / Reactivity Mouse (Murine) Rat (Rattus) Human
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 1 Antibodies
Cytometry by Time of Flight (CyTOF) 1 Antibodies
Western Blotting (WB) 81 Antibodies 67 Antibodies 167 Antibodies
Intracellular Staining (ICS) 6 Antibodies
Immunoprecipitation (IP) 12 Antibodies 9 Antibodies 29 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 47 Antibodies 14 Antibodies 10 Antibodies
Immunohistochemistry (IHC) 20 Antibodies 4 Antibodies 3 Antibodies

General

Antigen Linker For Activation of T Cells (LAT) Antibodies
Epitope C-Term
(24), (19), (19), (17), (11), (10), (9), (8), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(242), (122), (106), (3), (2), (2), (1), (1)
Host Goat
(142), (109), (12), (2)
Clonality
Polyclonal
Conjugate This LAT antibody is un-conjugated
(9), (9), (8), (8), (8), (6), (5), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(189), (68), (51), (47), (39), (39), (21), (21), (14), (6), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-LAT Antibody

Target Details LAT Application Details Handling References for anti-LAT Antibody (ABIN374446) Images
Sequence C-GAPDYENLQE LN
Specificity This antibody is expected to recognize isoform a (NP_055202.1), isoform b (NP_001014987.1 and NP_001014989.1) and isoform c (NP_001014988.1).
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse and Rat.
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Immunogen Peptide from the C Terminus of the protein sequence according to NP_055202.1, NP_001014987.1, NP_001014989.1, NP_001014988.1

Target Details LAT

Product Details anti-LAT Antibody Application Details Handling References for anti-LAT Antibody (ABIN374446) Images back to top
Antigen
Alternative Name LAT (LAT Antibody Abstract)
Background Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.Synonyms: 36 kDa Phospho-Tyrosine Adapter Protein, Linker For Activation of T-Cells Family Member 1, p36-38, pp36
Molecular Weight 27.9kDa (NP_055202.1).
Gene ID 27040
NCBI Accession NP_001014987
UniProt O43561
Research Area Signaling, Adaptive Immunity
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-LAT Antibody Target Details LAT Handling References for anti-LAT Antibody (ABIN374446) Images back to top
Application Notes Peptide ELISA: 1/2,000. Western Blot: 1-3 μg/mL. Detects a band of Approx 35 kDa in Human PBMC lysates(Predicted Molecular Weight: 35 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-LAT Antibody Target Details LAT Application Details References for anti-LAT Antibody (ABIN374446) Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C.

References for anti-LAT Antibody (ABIN374446)

Product Details anti-LAT Antibody Target Details LAT Application Details Handling Images back to top
Background publications

Finco, Kadlecek, Zhang, Samelson, Weiss: "LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway." in: Immunity, Vol. 9, Issue 5, pp. 617-26, 1998

Images

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Supplier Images
 image for anti-LAT antibody (Linker For Activation of T Cells) (C-Term) (ABIN374446) anti-Linker For Activation of T Cells (LAT) (C-Term) antibody