Browse our anti-PRKCE (PRKCE) Antibodies

Full name:
anti-Protein Kinase C, epsilon Antibodies (PRKCE)
On are 193 Protein Kinase C, epsilon (PRKCE) Antibodies from 27 different suppliers available. Additionally we are shipping PRKCE Kits (50) and PRKCE Proteins (22) and many more products for this protein. A total of 273 PRKCE products are currently listed.
5830406C15Rik, fj59b07, nPKC-epsilon, pkc-epsilon, Pkce, PKCepsilon, PKC[e], prkce, PRKCH, R75156, wu:fj59b07
list all antibodies Gene Name GeneID UniProt
PRKCE 5581 Q02156
PRKCE 18754 P16054
PRKCE 29340 P09216

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anti-Human PRKCE Antibodies:

anti-Mouse (Murine) PRKCE Antibodies:

anti-Rat (Rattus) PRKCE Antibodies:

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Top referenced anti-PRKCE Antibodies

  1. Chicken Monoclonal PRKCE Primary Antibody for IF, IP - ABIN967734 : Balafanova, Bolli, Zhang, Zheng, Pass, Bhatnagar, Tang, Wang, Cardwell, Ping: Nitric oxide (NO) induces nitration of protein kinase Cepsilon (PKCepsilon ), facilitating PKCepsilon translocation via enhanced PKCepsilon -RACK2 interactions: a novel mechanism of no-triggered activation of PKCepsilon. in The Journal of biological chemistry 2002 (PubMed)
    Show all 6 references for 967734

  2. Human Polyclonal PRKCE Primary Antibody for EIA, IHC (p) - ABIN359064 : Gray, Zhou, Schafhalter-Zoppoth, Zhu, Mochly-Rosen, Messing: Preservation of base-line hemodynamic function and loss of inducible cardioprotection in adult mice lacking protein kinase C epsilon. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for 359064

  3. Mouse (Murine) Polyclonal PRKCE Primary Antibody for ELISA, WB - ABIN1574296 : Breitkreutz, Braiman-Wiksman, Daum, Denning, Tennenbaum: Protein kinase C family: on the crossroads of cell signaling in skin and tumor epithelium. in Journal of cancer research and clinical oncology 2007 (PubMed)
    Show all 3 references for 1574296

  4. Human Polyclonal PRKCE Primary Antibody for ELISA, WB - ABIN1532522 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

  5. Human Polyclonal PRKCE Primary Antibody for IHC (p), WB - ABIN391007 : Tang, Bouyer, Mykoniatis, Buschmann, Matlin, Matthews: Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1. in The Journal of biological chemistry 2010 (PubMed)

More Antibodies against PRKCE Interaction Partners

Human Protein Kinase C, epsilon (PRKCE) interaction partners

  1. PKCdelta (show PKCd Antibodies) and PKCepsilon work as a functional couple with opposite roles on thrombopoiesis, and the modulation of their balance strongly impacts platelet production.

  2. Curcumin inhibited phorbol ester-induced membrane translocation of protein kinase C-epsilon (PKCepsilon) mutants, in which the epsilonC1 domain was replaced with alphaC1, but not the protein kinase C-alpha (PKCalpha (show PKCa Antibodies)) mutant in which alphaC1 was replaced with the epsilonC1 domain, suggesting that alphaC1 is a determinant for curcumin's inhibitory effect.

  3. we demonstrate that PKCepsilon cooperates with the loss of the tumor suppressor Pten (show PTEN Antibodies) for the development of prostate cancer in a mouse model. Mechanistic analysis revealed that PKCe overexpression and Pten (show PTEN Antibodies) loss individually and synergistically upregulate the production of the chemokine (show CCL1 Antibodies) CXCL13 (show CXCL13 Antibodies), which involves the transcriptional activation of the CXCL13 (show CXCL13 Antibodies) gene

  4. These results indicate that PKC (show PRRT2 Antibodies) promotes synaptogenesis by activating PSD-95 (show DLG4 Antibodies) phosphorylation directly through JNK1 (show MAPK8 Antibodies) and calcium/calmodulin-dependent kinase (show CAMK2 Antibodies) II and also by inducing expression of PSD-95 (show DLG4 Antibodies) and synaptophysin (show SYP Antibodies).

  5. epsilonPKC phosphorylation and its coevolution with ALDH2 (show ALDH2 Antibodies) play an important role in the regulation and protection of ALDH2 (show ALDH2 Antibodies) enzyme activity.

  6. PKCepsilon down-regulation suppresses sorting and the cancer stem-like phenotype of renal cell carcinoma (show MOK Antibodies) 769P side population cells through the regulation of ABCB1 (show ABCB1 Antibodies) transporter and the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies), Stat3 (show STAT3 Antibodies) and MAPK/ERK (show MAPK1 Antibodies) pathways that are dependent on the phosphorylation effects.

  7. PRKCE plays two major roles in cardiac muscle cells: it takes part in regulating cardiac muscle contraction via targeting the sarcomeric proteins, as well as it modulates cardiac cell energy production and metabolism by targeting cardiac mitochondria. (Review)

  8. PKCepsilon is a key factor for driving the formation of bone metastasis by prostate cancer cells and is a potential therapeutic target for advanced stages of the disease.

  9. Docosahexaenoic acid increase the efficacy of docetaxel in mammary cancer cells by downregulating Akt (show AKT1 Antibodies) and PKCepsilon/delta-induced ERK (show EPHB2 Antibodies) pathways.

  10. Depletion of PKCepsilon not only enhanced HGF-induced phosphorylation of JNK and paxillin (Ser178) but also prevented c-Met degradation.

Mouse (Murine) Protein Kinase C, epsilon (PRKCE) interaction partners

  1. that PKC-epsilon activation mediates 1) dysfunction of complexes I and III of the respiratory chain, 2) oxidant production, 3) morphological damage to the kidney, and 4) decreases in renal functions after ischemia

  2. Sstudy provides evidence that PKCepsilon-ALDH2 (show ALDH2 Antibodies) pathway positively regulates adipocyte differentiation by regulation of PPARgamma (show PPARG Antibodies) transcriptional activity.

  3. Data suggest that PKCe positively regulates beta-catenin (show CTNNB1 Antibodies) expression and stabilization in a glycogen synthase kinase 3beta-independent manner; beta-catenin (show CTNNB1 Antibodies) exhibits a perinuclear localization pattern in podocytes; however, beta-catenin (show CTNNB1 Antibodies) is predominantly localized to nucleus in podocytes from PKCe knockout mice. (PKCe = protein kinase C epsilon)

  4. Results demonstrate that specific inhibition of PKCepsilon reduces ethanol consumption and prolongs ethanol intoxication, support the development of inhibitors of PKCepsilon catalytic activity as a strategy to reduce ethanol consumption, and they demonstrate that the AS- PKCepsilon mouse is a useful tool to study the role of PKCepsilon in behavior.

  5. inhibition of mu-opioid receptor expression blocks morphine and DAMGO increases in the translocation of NF-kB p65 protein in microglia.a low dose of morphine, exerting its effects via the mu-opioid receptor, increases the DNA-binding activity of NF-kB via PKCepsilon, while a high dose of morphine triggers a nonopiate receptor response mediated by TLR4 and, interestingly, PKC signalling

  6. PKCepsilon signaling in both the nucleus accumbens and central nucleus of the amygdala is a major contributor to binge alcohol drinking and to the genetic propensity to consume excessive amounts of alcohol.

  7. with strain there was significant PKCepsilon translocation to the Z-disc and co-localization with CapZbeta1 or alpha-actinin (show ACTN1 Antibodies), which was quantified on confocal images.

  8. Protein kinase C epsilon phosphorylates the alpha4 nAChR (show CHRNA4 Antibodies) subunit and regulates recovery from receptor desensitization.

  9. PKCepsilon-CREB (show CREB1 Antibodies)-Nrf2 (show NFE2L2 Antibodies) signalling induces HO-1 (show HMOX1 Antibodies) in the vascular endothelium and enhances resistance to inflammation and apoptosis.

  10. acidosis in inflamed tissues may be a decisive factor to regulate switching of PKA and PKCepsilon dependence via proton-sensing G-protein-coupled receptors.

Cow (Bovine) Protein Kinase C, epsilon (PRKCE) interaction partners

  1. These data identify PKCepsilon as a key regulator of cilia slowing in response to combined smoke and alcohol-induced lung injury.

  2. deltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS (show NOS3 Antibodies) post-translational modification

  3. Differential expression of protein kinase C epsilon and an elevation of [Ca(2 (show CA2 Antibodies)+)]i are important for acquisition of luteolytic response to PGF2 alpha

  4. By regulating VEGFR2 (show KDR Antibodies) expression and activation, PKC-epsilon expression is critical for activation of Akt (show AKT1 Antibodies) and eNOS (show NOS3 Antibodies) by VEGF (show VEGFA Antibodies) and contributes to VEGF (show VEGFA Antibodies)-stimulated Erk (show MAPK1 Antibodies) activation, whereas PKC-alpha (show PKCa Antibodies) has opposite effects.

Rabbit Protein Kinase C, epsilon (PRKCE) interaction partners

  1. Activation of PKC (show PKC Antibodies) induces the translocation of Nrf2 (show NFE2L2 Antibodies) and the enhancement of endogenous antioxidant defenses in ischemic preconditioned rabbit heart.

  2. in contrast to protective effects of PKC-epsilon activation in cardiomyocytes, sustained PKC-epsilon activation is detrimental to mitochondrial function and viability in renal proximal tubule cells

  3. Preferential glucose utilization by PKCepsilon hearts is orchestrated by a p-GSK3beta (show GSK3b Antibodies)/HIF-1alpha (show HIF1A Antibodies)-mediated mechanism.

PRKCE Antigen Profile

Antigen Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

Alternative names and synonyms associated with PRKCE

  • protein kinase C, epsilon (PRKCE) antibody
  • protein kinase C, epsilon a (prkcea) antibody
  • protein kinase C, epsilon (prkce) antibody
  • protein kinase C, epsilon (Prkce) antibody
  • 5830406C15Rik antibody
  • fj59b07 antibody
  • nPKC-epsilon antibody
  • pkc-epsilon antibody
  • Pkce antibody
  • PKCepsilon antibody
  • PKC[e] antibody
  • prkce antibody
  • PRKCH antibody
  • R75156 antibody
  • wu:fj59b07 antibody

Protein level used designations for PRKCE

protein kinase C epsilon type , protein kinase C, epsilon , protein kinase C epsilon type-like , npkc-epsilon , pkc epsilon , nPKC-epsilon , PKC-epsilon , protein kinase C, eta

714533 Macaca mulatta
100468967 Ailuropoda melanoleuca
100005075 Danio rerio
100135720 Xenopus (Silurana) tropicalis
100440778 Pongo abelii
100543758 Meleagris gallopavo
100567346 Anolis carolinensis
100606298 Nomascus leucogenys
5581 Homo sapiens
18754 Mus musculus
29340 Rattus norvegicus
507041 Bos taurus
100009103 Oryctolagus cuniculus
449005 Sus scrofa
609934 Canis lupus familiaris
421409 Gallus gallus
101110314 Ovis aries
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