anti-Human VAV1 antibody for Flow Cytometry

Recommended VAV1 Antibody (supplied by: Log in to see )

Antigen
Vav 1 Oncogene (VAV1) Antibodies
  • VAV
  • Vav
  • vav-T
  • vav 1 guanine nucleotide exchange factor
  • vav 1 oncogene
  • VAV1
  • Vav1
  • vav1
Epitope
AA 121-324
37
25
23
20
15
10
9
8
6
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
184
76
73
4
4
2
2
2
2
1
Host
Mouse
135
50
Clonality
Monoclonal
Conjugate
This VAV1 antibody is un-conjugated
5
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
157
70
26
22
14
14
11
6
3
1
1
1
1
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Catalog No. ABIN969581
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.996978 ABIN4364878 CyTOF ELISA FACS WB Mouse IgG1 Log in to see 2E11
13.996978 ABIN1845807 FACS ELISA WB Mouse IgG1 AA 121-324 Log in to see
1 ABIN1490879 FACS ELISA WB Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN4881134 ELISA FACS WB Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN229274 FACS IP ELISA WB Rabbit IgG pTyr174 Log in to see Polyclonal
1 ABIN5600167 ELISA FACS WB DyLight 405 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600173 ELISA FACS FITC Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600161 ELISA FACS WB Alexa Fluor 488 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600160 ELISA FACS WB Alexa Fluor 405 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600176 FACS PE Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600164 FACS Allophycocyanin Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600175 FACS PerCP Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600163 ELISA FACS WB Alexa Fluor 700 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600162 ELISA FACS WB Alexa Fluor 647 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600166 ELISA FACS WB DyLight 350 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600169 ELISA FACS WB DyLight 550 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600168 ELISA FACS WB DyLight 488 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600172 ELISA FACS WB DyLight 755 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600170 ELISA FACS WB DyLight 650 Mouse IgG1 AA 121-324 Log in to see 2E11
1 ABIN5600171 ELISA FACS WB DyLight 680 Mouse IgG1 AA 121-324 Log in to see 2E11

General

Antigen Vav 1 Oncogene (VAV1) Antibodies
Epitope AA 121-324
(37), (25), (23), (20), (15), (10), (9), (8), (6), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(184), (76), (73), (4), (4), (2), (2), (2), (2), (1)
Host Mouse
(135), (50)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VAV1 antibody is un-conjugated
(5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(157), (70), (26), (22), (14), (14), (11), (6), (3), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-VAV1 Antibody

Target Details VAV1 Application Details Handling References for anti-VAV1 antibody (ABIN969581) Images
Purification Purified
Immunogen Purified recombinant fragment of human VAV1 (AA 121-324) expressed in E. Coli.
Clone 2-00E-11
Isotype IgG1

Target Details VAV1

Product Details anti-VAV1 Antibody Application Details Handling References for anti-VAV1 antibody (ABIN969581) Images back to top
Antigen
Alternative Name VAV1 (VAV1 Antibody Abstract)
Background The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.
Molecular Weight 98.3 kDa
Gene ID 7409
HGNC 7409
Research Area Cancer, Transcription Factors
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events

Application Details

Product Details anti-VAV1 Antibody Target Details VAV1 Handling References for anti-VAV1 antibody (ABIN969581) Images back to top
Application Notes ELISA: 1:10000, WB: 1:250, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details References for anti-VAV1 antibody (ABIN969581) Images back to top
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-VAV1 antibody (ABIN969581)

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling Images back to top
Product cited in:

Bertagnolo, Nika, Brugnoli, Bonora, Grassilli, Pinton, Capitani: "Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells." in: Cell and tissue research, Vol. 345, Issue 1, pp. 163-75, 2011

Yin, Wan, Li, Du, Zhang, Zhou, Cao: "The distinct role of guanine nucleotide exchange factor Vav1 in Bcl-2 transcription and apoptosis inhibition in Jurkat leukemia T cells." in: Acta pharmacologica Sinica, Vol. 32, Issue 1, pp. 99-107, 2011

Images

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling References for anti-VAV1 antibody (ABIN969581) back to top
Supplier Images
ELISA image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 2: Flow cytometric analysis of HeLa cells using VAV1 mouse mAb (green) and neg...
Western Blotting (WB) image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 3: Western blot analysis using VAV1 mouse mAb against Jurkat (1) cell lysate.
Western Blotting (WB) image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 4: Western blot analysis using VAV1 mAb against human VAV1 recombinant protein...
Western Blotting (WB) image for anti-Vav 1 Oncogene (VAV1) (AA 121-324) antibody (ABIN969581) Figure 5: Western blot analysis using VAV1 mAb against HEK293 (1) and VAV1 (AA: 121-3...