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anti-Human VAV1 antibody for Immunocytochemistry

Recommended VAV1 Antibody (supplied by: Log in to see )

Antigen
Vav 1 Oncogene (VAV1) Antibodies
  • VAV
  • Vav
  • vav-T
Epitope
C-Term
35
21
19
15
13
12
5
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
143
64
63
1
1
1
Host
Rabbit
128
15
Clonality
Monoclonal
Conjugate
This VAV1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
120
57
25
12
10
10
7
3
1
1
1
1
Supplier
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Available images

Catalog No. ABIN258533
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0009962841 ABIN4364879 ICC IF IHC IHC (p) Rabbit IgG Log in to see Polyclonal

Similar anti-VAV1 Antibodies

Application / Reactivity Human
ELISA 57 Antibodies
ELISA (Capture) 1 Antibodies
Flow Cytometry (FACS) 7 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies
Immunohistochemistry (IHC) 26 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 122 Antibodies

General

Antigen Vav 1 Oncogene (VAV1) Antibodies
Epitope C-Term
(35), (21), (19), (15), (13), (12), (5), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(143), (64), (63), (1), (1), (1)
Host Rabbit
(128), (15)
Clonality (Clone)
Monoclonal   ( )
Conjugate This VAV1 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(120), (57), (25), (12), (10), (10), (7), (3), (1), (1), (1), (1)
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Product Details anti-VAV1 Antibody

Target Details VAV1 Application Details Handling Images
No Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification IgG purified
Immunogen A synthetic peptide corresponding to residues near the C-terminus of human Vav was used as an immunogen.
Clone EP482Y
Isotype IgG

Target Details VAV1

Product Details anti-VAV1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name VAV1 (VAV1 Antibody Abstract)
Background The Vav family are Rho/Rac guanosine nucleotide exchange factors (GEFs), consistingof three members in mammalian cells (Vav, Vav2, Vav3) and one in nematodes(CelVav) (1). First discovered based on its transforming properties, Vav is expressedmainly in hematopoietic cells and a few non-hematopoietic tissues, such as thepancreas and tooth enamels (2). As a signaling transducer, Vav is involved in T-cellactivated transduction of T-cell antigen receptor (TCR). T-cell stimulated and tyrosinephosphorylated Vav acts as a catalyst in the exchange of guanosine nucleotides onRac-1, a GTP binding protein (3). Using a mouse model, Vav expression has beendetermined to play an essential role in the cyctosketetal, proliferative, and apoptoticpathways for developing lymphoid cells and its signal response (2). Alternate Names: anti-Vav 3 oncogene antibody, anti-Protein vav 2 antibody, anti-Protein vav 3 antibody,anti-Proto oncogene vav antibody, anti-VAV antibody, anti-Vav 1 oncogene antibody,anti-Vav 2 oncogene antibody.
Gene Symbol: VAV1
Gene ID 7409, 22324, 25156
Research Area Cancer, Transcription Factors
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-VAV1 Antibody Target Details VAV1 Handling Images back to top
Application Notes This product is useful for: Western Blot, Immunocytochemistry, Immunoprecipitation. In Western blot this antibody detects a band at approximately 95kDa.
Recommended dilutions: Immunocytochemistry/Immunofluorescence 1:50, Immunoprecipitation 1:50, Western Blot 1:2000
Restrictions For Research Use only

Handling

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Images back to top
Format Liquid
Buffer PBS 49 % , Glycerol 50 % , BSA 0.05 % , Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment -20 °C.

Images

Product Details anti-VAV1 Antibody Target Details VAV1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-VAV1 antibody (Vav 1 Oncogene) (C-Term) (ABIN258533) Western blot analysis on Jurkat cell lysate using anti-Vav RabMAb (cat. # 110-57639),...