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Browse our Thyroperoxidase Proteins (TPO)

Full name:
Thyroid Peroxidase Proteins (TPO)
On www.antibodies-online.com are 50 Thyroid Peroxidase (TPO) Proteins from 14 different suppliers available. Additionally we are shipping Thyroperoxidase Antibodies (209) and Thyroperoxidase Kits (72) and many more products for this protein. A total of 339 Thyroperoxidase products are currently listed.
Synonyms:
LOC100218312, MSA, TDH2A, TPO, TPX, xtpo
list all proteins Gene Name GeneID UniProt
TPO 7173 P07202
TPO 22018 P35419
TPO 54314  

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Thyroperoxidase Proteins (TPO) by Origin

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Top referenced Thyroperoxidase Proteins

  1. Human Thyroperoxidase Protein expressed in Escherichia coli (E. coli) - ABIN413833 : Kinzfogl, Hangoc, Broxmeyer: Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells. in Blood 2011 (PubMed)

More Proteins for Thyroperoxidase Interaction Partners

Human Thyroid Peroxidase (TPO) interaction partners

  1. The results of the study suggest that rs11675434 SNP located near TPO (show THPO Proteins) is associated with the development of Graves ophthalmopathy, especially in males and patients with later age of the disease onset.

  2. Mutations in the TPO (show THPO Proteins) gene are associated with Congenital hypothyroidism and thyroid dyshormonogenesis.

  3. Compound heterozygous mutations in the TPO (show THPO Proteins) gene are associated with congenital hypothyroidism.

  4. Mutations in the genes for thyroglobulin (show TG Proteins) and thyroid peroxidase cause thyroid dyshormonogenesis and autosomal-recessive intellectual disability

  5. Studies suggest that Thyroid Peroxidase autoantibodies in early to mid-pregnancy is associated with concurrent depression and may be predictive of depression in the postpartum period.

  6. Anti-thyroid peroxidase (TPO) antibodies and male gender were significantly associated with glucose impairment in patients with beta thalassemia major.

  7. Lower pretreatment serum CXCL10 (show CXCL10 Proteins) levels are associated with thyroid dysfunction. Thyroid dysfunction prevalence increases in female patients and patients who are positive for TPOAb at baseline.

  8. Two novel inactivating mutations (c.1970T> C and c.2665G> T) in the TPO (show THPO Proteins) gene cause congenital hypothyroidism.

  9. function and autoantigenicity of TPO (show THPO Proteins)

  10. This study confirms the pathogenicity of Y55X mutation in two patients with congenital hypothyroidism and demonstrates that a nonsense mutation in the amino-terminal coding region of the TPO (show THPO Proteins) gene could totally abolish the function of the TPO (show THPO Proteins) enzyme leading to total iodide organification defect.

Mouse (Murine) Thyroid Peroxidase (TPO) interaction partners

  1. Hearing impairment in hypothyroid dwarf (show POU1F1 Proteins) mice caused by mutations of the thyroid peroxidase gene.

  2. Findings demonstrate a novel aspect of murine and human thyroid autoimmunity, namely breaking B cell self-tolerance occurs first for Tg and subsequently for TPO (show THPO Proteins).

  3. A novel hypothyroid dwarfism is due to the missense mutation Arg479Cys of the thyroid peroxidase gene in the mouse.

Pig (Porcine) Thyroid Peroxidase (TPO) interaction partners

  1. TPO gene was mapped

Thyroperoxidase (TPO) Protein Profile

Protein Summary

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.

Alternative names and synonyms associated with Thyroperoxidase (TPO)

  • thyroid peroxidase (TPO)
  • thyroid peroxidase (tpo)
  • thyroid peroxidase (LOC100218312)
  • thyroid peroxidase (Tpo)
  • LOC100218312 protein
  • MSA protein
  • TDH2A protein
  • TPO protein
  • TPX protein
  • xtpo protein

Protein level used designations for Thyroid Peroxidase Proteins (TPO)

thyroid peroxidase , thyroid peroxidase-like , thyroid microsomal antigen , thyroperoxidase , thyroid peroxidase (332 AA)

GENE ID SPECIES
721610 Macaca mulatta
100036738 Xenopus (Silurana) tropicalis
100218312 Taeniopygia guttata
100386952 Callithrix jacchus
100456793 Pongo abelii
100547103 Meleagris gallopavo
100600125 Nomascus leucogenys
7173 Homo sapiens
22018 Mus musculus
54314 Rattus norvegicus
525013 Bos taurus
403521 Canis lupus familiaris
445522 Sus scrofa
776120 Gallus gallus
100723704 Cavia porcellus
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