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Browse our Thyroperoxidase Proteins (TPO)

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Thyroid Peroxidase Proteins (TPO)
On are 57 Thyroid Peroxidase (TPO) Proteins from 15 different suppliers available. Additionally we are shipping Thyroperoxidase Antibodies (211) and Thyroperoxidase Kits (72) and many more products for this protein. A total of 347 Thyroperoxidase products are currently listed.
LOC100218312, MSA, TDH2A, TPO, TPX, xtpo
list all proteins Gene Name GeneID UniProt
TPO 7173 P07202
TPO 22018 P35419
TPO 54314  

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Thyroperoxidase Proteins (TPO) by Origin

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Top referenced Thyroperoxidase Proteins

  1. Human Thyroperoxidase Protein expressed in Escherichia coli (E. coli) - ABIN413833 : Kinzfogl, Hangoc, Broxmeyer: Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells. in Blood 2011 (PubMed)

More Proteins for Thyroperoxidase Interaction Partners

Human Thyroid Peroxidase (TPO) interaction partners

  1. Studies suggest that Thyroid Peroxidase autoantibodies in early to mid-pregnancy is associated with concurrent depression and may be predictive of depression in the postpartum period.

  2. Anti-thyroid peroxidase (TPO) antibodies and male gender were significantly associated with glucose impairment in patients with beta thalassemia major.

  3. Lower pretreatment serum CXCL10 (show CXCL10 Proteins) levels are associated with thyroid dysfunction. Thyroid dysfunction prevalence increases in female patients and patients who are positive for TPOAb at baseline.

  4. Two novel inactivating mutations (c.1970T> C and c.2665G> T) in the TPO (show THPO Proteins) gene cause congenital hypothyroidism.

  5. function and autoantigenicity of TPO (show THPO Proteins)

  6. This study confirms the pathogenicity of Y55X mutation in two patients with congenital hypothyroidism and demonstrates that a nonsense mutation in the amino-terminal coding region of the TPO (show THPO Proteins) gene could totally abolish the function of the TPO (show THPO Proteins) enzyme leading to total iodide organification defect.

  7. analysis of thyroid peroxidase autoantibody levels in type 1 diabetes in discordant twin pairs

  8. Data show that thyroperoxidase (TPO) single nucleotide polymorphisms (SNPs) rs4927611 TT and rs732609 CC are genotypes associated with potential risk for the congenital hypothyroidism (CH).

  9. A single base deletion in the carboxyl-terminal coding region of the TPO (show THPO Proteins) gene could cause congenital hypothyroidism and helps to establish a genotype/phenotype correlation associated with the mutation.

  10. Molecular cloning and functional studies of wild type and mutant forms harboring missense mutations in TPO (show THPO Proteins) gene showed decreased activity in the three mutants, higher Km values and lower reaction efficiencies (Vmax/Km).

Mouse (Murine) Thyroid Peroxidase (TPO) interaction partners

  1. Hearing impairment in hypothyroid dwarf (show POU1F1 Proteins) mice caused by mutations of the thyroid peroxidase gene.

  2. Findings demonstrate a novel aspect of murine and human thyroid autoimmunity, namely breaking B cell self-tolerance occurs first for Tg and subsequently for TPO (show THPO Proteins).

  3. A novel hypothyroid dwarfism is due to the missense mutation Arg479Cys of the thyroid peroxidase gene in the mouse.

Pig (Porcine) Thyroid Peroxidase (TPO) interaction partners

  1. TPO gene was mapped

Thyroperoxidase (TPO) Protein Profile

Protein Summary

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.

Alternative names and synonyms associated with Thyroperoxidase (TPO)

  • thyroid peroxidase (TPO)
  • thyroid peroxidase (tpo)
  • thyroid peroxidase (LOC100218312)
  • thyroid peroxidase (Tpo)
  • LOC100218312 protein
  • MSA protein
  • TDH2A protein
  • TPO protein
  • TPX protein
  • xtpo protein

Protein level used designations for Thyroid Peroxidase Proteins (TPO)

thyroid peroxidase , thyroid peroxidase-like , thyroid microsomal antigen , thyroperoxidase , thyroid peroxidase (332 AA)

721610 Macaca mulatta
100036738 Xenopus (Silurana) tropicalis
100218312 Taeniopygia guttata
100386952 Callithrix jacchus
100456793 Pongo abelii
100547103 Meleagris gallopavo
100600125 Nomascus leucogenys
7173 Homo sapiens
22018 Mus musculus
54314 Rattus norvegicus
525013 Bos taurus
403521 Canis lupus familiaris
445522 Sus scrofa
776120 Gallus gallus
100723704 Cavia porcellus
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