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Thyroperoxidase Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

TPO Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733688
  • Target See all Thyroperoxidase (TPO) Proteins
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 8
    • 6
    • 2
    Human
    Source
    • 6
    • 5
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Thyroperoxidase protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Thyroid peroxidase (TPO) (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TPO Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Abstract
    TPO Products
    Synonyms
    MSA Protein, TDH2A Protein, TPX Protein, TPO Protein, msa Protein, tpx Protein, xtpo Protein, LOC100218312 Protein, thyroid peroxidase Protein, TPO Protein, Tpo Protein, tpo Protein, LOC100547103 Protein
    Background
    This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
    Molecular Weight
    102.8 kDa
    NCBI Accession
    NP_000538
    Pathways
    Thyroid Hormone Synthesis
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