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Browse our anti-TAB1 (TAB1) Antibodies

Full name:
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 Antibodies (TAB1)
On www.antibodies-online.com are 173 TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Antibodies from 26 different suppliers available. Additionally we are shipping TAB1 Proteins (7) and TAB1 Kits (3) and many more products for this protein. A total of 193 TAB1 products are currently listed.
Synonyms:
3'-Tab1, 2310012M03Rik, b2b449Clo, Map3k7ip1
list all antibodies Gene Name GeneID UniProt
TAB1 10454 Q15750
TAB1 66513 Q8CF89
TAB1 315139  

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anti-Human TAB1 Antibodies:

anti-Mouse (Murine) TAB1 Antibodies:

anti-Rat (Rattus) TAB1 Antibodies:

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Top referenced anti-TAB1 Antibodies

  1. Human Monoclonal TAB1 Primary Antibody for WB - ABIN393632 : McGovern, Jones, Taylor, Marciante, Yan, Dubinsky, Ippoliti, Vasiliauskas, Berel, Derkowski, Dutridge, Fleshner, Shih, Melmed, Mengesha, King, Pressman, Haritunians, Guo, Targan, Rotter,: Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. in Human molecular genetics 2010 (PubMed)
    Show all 5 references for ABIN393632

  2. Human Monoclonal TAB1 Primary Antibody for IF, WB - ABIN393549 : Scholz, Sidler, Thali, Winssinger, Cheung, Neumann: Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular process. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN393549

  3. Human Polyclonal TAB1 Primary Antibody for EIA, WB - ABIN401658 : Arch, Gedrich, Thompson: Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death. in Genes & development 1998 (PubMed)
    Show all 2 references for ABIN401658

  4. Human Polyclonal TAB1 Primary Antibody for EIA, WB - ABIN453175 : Yamaguchi, Nagai, Ninomiya-Tsuji, Nishita, Tamai, Irie, Ueno, Nishida, Shibuya, Matsumoto: XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. in The EMBO journal 1999 (PubMed)
    Show all 2 references for ABIN453175

  5. Human Polyclonal TAB1 Primary Antibody for IF, IHC (p) - ABIN303281 : Shibuya, Yamaguchi, Shirakabe, Tonegawa, Gotoh, Ueno, Irie, Nishida, Matsumoto: TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. in Science (New York, N.Y.) 1996 (PubMed)

  6. Chicken Polyclonal TAB1 Primary Antibody for WB - ABIN2785275 : Neil, Schiemann: Altered TAB1:I kappaB kinase interaction promotes transforming growth factor beta-mediated nuclear factor-kappaB activation during breast cancer progression. in Cancer research 2008 (PubMed)

More Antibodies against TAB1 Interaction Partners

Human TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) interaction partners

  1. miR (show MLXIP Antibodies)-29a repressed TAB1-mediated TIMP-1 (show TIMP1 Antibodies) production in dermal fibroblasts, demonstrating that miR (show MLXIP Antibodies)-29a may be a therapeutic target in SSc (show CYP11A1 Antibodies).

  2. Data indicate that mitogen-activated protein kinase (show MAPK1 Antibodies) (MAPK) p38 (show MAPK1 Antibodies) activation is triggered by AMP (show APRT Antibodies)-activated protein kinases (AMPK (show PRKAA1 Antibodies)) and mediated by TAB1 protein.

  3. The amino acid sequence between positions 373 and 502 of TAB1 is required for TP interaction.

  4. USP18 (show USP18 Antibodies) inhibits NF-kappaB (show NFKB1 Antibodies) and NFAT (show NFATC1 Antibodies) activation during Th17 differentiation by deubiquitinating the TAK1 (show MAP3K7 Antibodies)-TAB1 complex.

  5. We found that endothelial TAK1 (show MAP3K7 Antibodies) and TAB2 (show TAB2 Antibodies), but not TAB1, were critically involved in vascular formation

  6. TAK1 (show MAP3K7 Antibodies) plays a critical role in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation.

  7. data suggest a complex role of aa 452-457 of TAB1 in controlling p38 MAPK (show MAPK14 Antibodies) activity and subcellular localization and implicate these residues in TAK1 (show MAP3K7 Antibodies)- or p38 MAPK (show MAPK14 Antibodies)-dependent post-transcriptional control of gene expression

  8. Phosphorylation and polyubiquitination of TAK1 (show MAP3K7 Antibodies) are necessary for activation of NF-kappaB (show NFKB1 Antibodies) by the Kaposi's sarcoma-associated herpesvirus vGPCR.

  9. Co-expression of TAK1 (show MAP3K7 Antibodies) and TAB1 resulted in a functional and active TAK1 (show MAP3K7 Antibodies)-TAB1 complex capable of directly activating full-length heterotrimeric mammalian AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)) in vitro.

  10. interaction with p38alpha (show MAPK14 Antibodies) leads to autophosphorylation and activation of p38alpha (show MAPK14 Antibodies)

Mouse (Murine) TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) interaction partners

  1. We confirmed that PGC (show PGC Antibodies)-1b inhibited downstream inflammatory signals via binding with TAB1 and thus preventing TAB1/TAK1 (show NR2C2 Antibodies) binding and TAK1 (show NR2C2 Antibodies) activation.

  2. The E3 ubiquitin ligase (show MUL1 Antibodies) Itch inhibits p38alpha (show MAPK14 Antibodies) signaling and skin inflammation through the ubiquitylation of Tab1.

  3. TAB1 and TAB2 (show TAB2 Antibodies) are required for activated macrophages, making TAB1 and TAB2 (show TAB2 Antibodies) effective targets to control inflammation by modulating macrophage survival.

  4. Both the MEKK1 (show MAP2K1 Antibodies) PHD (show PDC Antibodies) and TAB1 are critical for ES-cell differentiation

  5. The enhanced JNK (show MAPK8 Antibodies) and IkappaB kinase (show CHUK Antibodies) activation in DUSP14 (show DUSP14 Antibodies)-deficient T cells was attenuated by TAB1 short hairpin RNA knockdown.

  6. TAB1 binding stabilizes active p38alpha (show MAPK14 Antibodies) and induces rearrangements within the activation segment by helical extension of the Thr (show TRH Antibodies)-Gly-Tyr (show TYR Antibodies) motif, allowing autophosphorylation in cis (show CISH Antibodies)

  7. We found that endothelial TAK1 (show NR2C2 Antibodies) and TAB2 (show TAB2 Antibodies), but not TAB1, were critically involved in vascular formation

  8. O-GlcNAcylation of TAB1 is required for full TAK1 (show NR2C2 Antibodies) activation upon stimulation with IL-1 (show IL1A Antibodies)/osmotic stress.

  9. Epithelial TAK1 (show NR2C2 Antibodies) activity is regulated through two unique, TAB1-dependent basal & TAB2 (show TAB2 Antibodies)-mediated stimuli-dependent mechanisms.

  10. XIAP (show XIAP Antibodies)-TAB1-TAK1 (show NR2C2 Antibodies) complex is dependent on NRAGE (show MAGED1 Antibodies) for IKK-alpha (show CHUK Antibodies)/beta phosphorylation and NF-kappaB (show NFKB1 Antibodies) activation.

TAB1 Antigen Profile

Antigen Summary

The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with TAB1

  • TGF-beta activated kinase 1/MAP3K7 binding protein 1 (TAB1) antibody
  • TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1) antibody
  • 3'-Tab1 antibody
  • 2310012M03Rik antibody
  • b2b449Clo antibody
  • Map3k7ip1 antibody

Protein level used designations for TAB1

TAK1-binding protein 1 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 , mitogen-activated protein kinase kinase kinase 7-interacting protein 1 , transforming growth factor beta-activated kinase-binding protein 1 , TGF-beta-activated kinase 1-binding protein 1 , Tak1-binding protein 1 , beta activated kinase-1 binding protein-1 , mitogen activated protein kinase kinase kinase 7 interacting protein 1 , mitogen-activated protein kinase kinase kinase 7 interacting protein 1

GENE ID SPECIES
10454 Homo sapiens
66513 Mus musculus
315139 Rattus norvegicus
100358246 Oryctolagus cuniculus
418014 Gallus gallus
481245 Canis lupus familiaris
519958 Bos taurus
100153785 Sus scrofa
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