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Browse our anti-Aconitase 1 (ACO1) Antibodies

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anti-Aconitase 1 Antibodies (ACO1)
On are 81 Aconitase 1 (ACO1) Antibodies from 9 different suppliers available. Additionally we are shipping Aconitase 1 Proteins (15) and Aconitase 1 Kits (11) and many more products for this protein. A total of 112 Aconitase 1 products are currently listed.
Aco-1, AI256519, Irebp, Irp1
list all antibodies Gene Name GeneID UniProt
ACO1 11428 P28271

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Most Popular Reactivities for anti-Aconitase 1 (ACO1) Antibodies

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anti-Mouse (Murine) Aconitase 1 Antibodies:

anti-Human Aconitase 1 Antibodies:

anti-Rat (Rattus) Aconitase 1 Antibodies:

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Top referenced anti-Aconitase 1 Antibodies

  1. Human Polyclonal Aconitase 1 Primary Antibody for ICC, IF - ABIN4277661 : Dongiovanni, Lanti, Gatti, Rametta, Recalcati, Maggioni, Fracanzani, Riso, Cairo, Fargion, Valenti: High fat diet subverts hepatocellular iron uptake determining dysmetabolic iron overload. in PLoS ONE 2015 (PubMed)
    Show all 2 references for ABIN4277661

  2. Human Polyclonal Aconitase 1 Primary Antibody for ELISA, WB - ABIN4277660 : Wang, Di, DAgostino, Torti, Torti: Excess capacity of the iron regulatory protein system. in The Journal of biological chemistry 2007 (PubMed)

More Antibodies against Aconitase 1 Interaction Partners

Mouse (Murine) Aconitase 1 (ACO1) interaction partners

  1. Using whole RNA sequencing of bone marrow cells in iron-overloaded mice, it was observed that Idh1 (show IDH1 Antibodies) and Aco1, enzymes involved in the TCA cycle, were elevated.

  2. The Irp1-/- mice develop polycythemia and pulmonary hypertension, and suggesting that Irp1 plays an essential role in erythropoiesis and in the pulmonary and cardiovascular systems.

  3. IRP1 and IRP2 (show IREB2 Antibodies) mutant mice rapidly succumb to systemic infection with Salmonella Typhimurium, a pathogenic bacterium that multiplies within macrophages, with increased bacterial burdens in liver and spleen.

  4. results uncover an unexpected protective role of IRP1 in pathological conditions associated with altered Fe-S metabolism

  5. Aco1 KD in fully differentiated 3T3-L1 adipocytes decreased lipogenic, Idh1 (show IDH1 Antibodies), Adipoq (show ADIPOQ Antibodies), and Glut4 (show SLC2A4 Antibodies) gene expression.

  6. impaired mitochondrial [Fe-S] cluster biogenesis in Mfrn1 (show SLC25A37 Antibodies)(gt/gt (show FABP6 Antibodies)) cells results in elevated IRP1 RNA-binding that attenuates ALAS2 (show ALAS2 Antibodies) mRNA translation and protoporphyrin accumulation

  7. Data indicate that JTR-009, a benzimidazole, operated by preventing iron-regulatory protein-1 (IRP1) from binding to the iron-responsive element (IRE) in APP (show APP Antibodies) mRNA.

  8. Human ACO1 is a moonlighting protein that has both aconitase (show ACO2 Antibodies) enzyme activity as well as an mRNA binding function.

  9. Aco1 is a moonlighting protein that has aconitase (show ACO2 Antibodies) activity as well as mRNA binding ability.

  10. IRP1 is the principal regulator of HIF2alpha (show EPAS1 Antibodies) mRNA translation

Aconitase 1 (ACO1) Antigen Profile

Antigen Summary

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity). Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding (By similarity).

Alternative names and synonyms associated with Aconitase 1 (ACO1)

  • aconitase 1 (Aco1) antibody
  • Aco-1 antibody
  • AI256519 antibody
  • Irebp antibody
  • Irp1 antibody

Protein level used designations for anti-Aconitase 1 (ACO1) Antibodies

IRE-BP 1 , citrate hydro-lyase , cytoplasmic aconitase , cytoplasmic aconitate hydratase , iron regulatory protein 1 , iron-responsive element-binding protein 1

11428 Mus musculus
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