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anti-Human Adenomatous Polyposis Coli antibody for Enzyme Immunoassay

Recommended Adenomatous Polyposis Coli Antibody (supplied by: Log in to see )

Antigen
Adenomatous Polyposis Coli (APC) Antibodies
  • AI047805
  • APC1
  • AU020952
  • AW124434
  • BTPS2
  • CC1
  • dp2
  • DP2
  • DP2.5
  • dp2.5
  • DP3
  • dp3
  • fap
  • fpc
  • GS
  • mAPC
  • Min
  • PPP1R46
  • RATAPC
  • xapc
Reactivity
Human, Mouse (Murine), Rat (Rattus)
152
89
57
6
4
2
2
1
1
Host
Rabbit
142
33
15
2
Clonality
Polyclonal
Conjugate
Un-conjugated
9
8
6
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
129
61
61
48
43
27
23
22
13
3
2
1
1
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Catalog No. ABIN265313
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088582124 ABIN2716236 EIA Rabbit IgG Log in to see Polyclonal

Similar anti-Adenomatous Polyposis Coli Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 12 Antibodies 33 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 3 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 20 Antibodies 23 Antibodies
Immunofluorescence (IF) 21 Antibodies 32 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 31 Antibodies 30 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 27 Antibodies 28 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 39 Antibodies
FLISA 1 Antibodies

General

Antigen Adenomatous Polyposis Coli (APC) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(152), (89), (57), (6), (4), (2), (2), (1), (1)
Host Rabbit
(142), (33), (15), (2)
Clonality
Polyclonal
Conjugate Un-conjugated
(9), (8), (6), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(129), (61), (61), (48), (43), (27), (23), (22), (13), (3), (2), (1), (1)
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Product details

Target details Application Details Handling Images
Specificity This antibody detects endogenous levels of APC / DP2.5 protein (region surrounding Gln2829).
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
Purity > 95 % pure by SDS-PAGE

Target details

Product details Application Details Handling Images back to top
Antigen
Alternative Name APC / DP2.5 (APC Antibody Abstract)
Background Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling. APC regulates ß-catenin levels through Wnt-signaling and is involved in actin cytoskeletal integrity, cell-cell adhesion and cell migration. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.Synonyms: Adenomatous polyposis coli protein, Deleted in polyposis 2.5
Molecular Weight approx. 310 kDa
Gene ID 324
NCBI Accession NP_000029
UniProt P25054
Research Area Coagulation
Pathways WNT Signaling

Application Details

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Application Notes ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product details Target details Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

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Supplier Images
 image for anti-Adenomatous Polyposis Coli (APC) antibody (ABIN265313) anti-Adenomatous Polyposis Coli (APC) antibody
 image for anti-Adenomatous Polyposis Coli (APC) antibody (ABIN265313) anti-Adenomatous Polyposis Coli (APC) antibody (Image 2)