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anti-Rat (Rattus) LEF1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended LEF1 Antibody (supplied by: Log in to see )

Antigen
Lymphoid Enhancer-Binding Factor 1 (LEF1) Antibodies
  • 3000002B05
  • AI451430
  • LEF-1
  • Lef-1
  • LEF1
  • TCF1ALPHA
  • TCF7L3
  • TCF10
Reactivity
Human, Mouse (Murine), Rat (Rattus)
118
32
24
7
4
4
3
2
1
1
1
1
1
Host
Rabbit
53
45
16
5
Clonality
Polyclonal
Conjugate
This LEF1 antibody is un-conjugated
3
3
3
3
3
3
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
108
62
20
12
5
4
3
2
2
1
1
1
1
Supplier
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Catalog No. ABIN735248
$ 269.50
Plus shipping costs $45.00

Top referenced anti-LEF1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-LEF1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 18 Antibodies 18 Antibodies 63 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 7 Antibodies 8 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 1 Antibodies 3 Antibodies
Western Blotting (WB) 21 Antibodies 29 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 5 Antibodies
Immunofluorescence (IF) 2 Antibodies
Biochemical Assay (BCA) 2 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 1 Antibodies

General

Antigen Lymphoid Enhancer-Binding Factor 1 (LEF1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(118), (32), (24), (7), (4), (4), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(53), (45), (16), (5)
Clonality
Polyclonal
Conjugate This LEF1 antibody is un-conjugated
(3), (3), (3), (3), (3), (3)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(108), (62), (20), (12), (5), (4), (3), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-LEF1 Antibody

Target Details LEF1 Application Details Handling References for anti-LEF1 Antibody (ABIN735248) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human LEF-1
Isotype IgG

Target Details LEF1

Product Details anti-LEF1 Antibody Application Details Handling References for anti-LEF1 Antibody (ABIN735248) Images back to top
Antigen
Alternative Name Lef-1 (LEF1 Antibody Abstract)
Background

Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP3. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity). Isoform 3 lacks the CTNNB1 interaction domain and may be an antagonist for Wnt signaling. Isoform 5 transcriptionally activates the fibronectin promoter, binds to and represses transcription from the E-cadherin promoter in a CTNNB1-independent manner, and is involved in reducing cellular aggregation and increasing cell migration of pancreatic cancer cells. Isoform 1 transcriptionally activates MYC and CCND1 expression and enhances proliferation of pancreatic tumor cells.

Subcellular location: Nucleus


Synonyms: LEF-1, TCF1, TCF7L3, TCF1ALPHA, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha, TCF1-alpha, LEF1
Gene ID 51176
UniProt Q9UJU2
Pathways WNT Signaling

Application Details

Product Details anti-LEF1 Antibody Target Details LEF1 Handling References for anti-LEF1 Antibody (ABIN735248) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-LEF1 Antibody Target Details LEF1 Application Details References for anti-LEF1 Antibody (ABIN735248) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-LEF1 Antibody (ABIN735248)

Product Details anti-LEF1 Antibody Target Details LEF1 Application Details Handling Images back to top
Product cited in:

Xu, Zhao, Zhang, Xu, Yang, Wang, Liu: "Resveratrol Attenuates Hyperoxia-induced Oxidative Stress, Inflammation and Fibrosis and Suppresses Wnt/β-catenin Signaling in Lungs of Neonatal Rats." in: Clinical and experimental pharmacology & physiology, 2015

Wang, Xie, Xie, Wan, Ma, Qi, Yang: "MiR-27a regulates Wnt/beta-catenin signaling through targeting SFRP1 in glioma." in: Neuroreport, Vol. 26, Issue 12, pp. 695-702, 2015

Song, Man, Wang, Bai, Wei, Liu, Liu, Gu, Wang: "The Regenerating Spinal Cord of Gecko Maintains Unaltered Expression of ?-Catenin Following Tail Amputation." in: Journal of molecular neuroscience : MN, 2014

Images

Product Details anti-LEF1 Antibody Target Details LEF1 Application Details Handling References for anti-LEF1 Antibody (ABIN735248) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-LEF1 antibody (Lymphoid Enhancer-Binding Factor 1) (ABIN735248) Formalin-fixed and paraffin embedded human colon carcinoma tissue labeled with Anti-L...
Immunohistochemistry (IHC) image for anti-LEF1 antibody (Lymphoid Enhancer-Binding Factor 1) (ABIN735248) Formalin-fixed and paraffin embedded rat liver tissue labeled with Anti-LEF-1 Polyclo...
SDS-PAGE (SDS) image for anti-LEF1 antibody (Lymphoid Enhancer-Binding Factor 1) (ABIN735248) L1 rat brain lysates L2 human colon carcinoma lysates probed with Anti IL-2R gamma/CD...
Western Blotting (WB) image for anti-LEF1 antibody (Lymphoid Enhancer-Binding Factor 1) (ABIN735248) Mouse lymph node lysates probed with Rabbit Anti-LEF-1 Polyclonal Antibody, Unconjuga...