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anti-Rat (Rattus) LRP5 antibody for Enzyme Immunoassay

Recommended LRP5 Antibody (supplied by: Log in to see )

Antigen
Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies
  • bmnd1
  • BMND1
  • evr1
  • EVR1
  • EVR4
  • evr4
  • HBM
  • hbm
  • lr3
  • LR3
  • LRP5
  • lrp5-A
  • LRP6
  • LRP7
  • lrp7
  • mKIAA4142
  • OPPG
  • oppg
  • OPS
  • ops
  • OPTA1
  • opta1
  • VBCH2
  • vbch2
  • Xlrp5
Epitope
Internal Region
41
16
13
13
13
11
5
4
3
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
98
59
39
1
1
1
1
1
Host
Goat
92
14
12
2
Clonality
Polyclonal
Conjugate
This LRP5 antibody is un-conjugated
8
8
7
5
5
5
3
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
76
59
32
23
13
6
3
3
2
2
2
Supplier
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Catalog No. ABIN374570
$ 379.50
Plus shipping costs $45.00

Top referenced anti-LRP5 antibody for Enzyme Immunoassay

Similar anti-LRP5 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 57 Antibodies 33 Antibodies 12 Antibodies
Immunoprecipitation (IP) 1 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies 9 Antibodies 8 Antibodies
Immunohistochemistry (IHC) 32 Antibodies 8 Antibodies 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 23 Antibodies 23 Antibodies 23 Antibodies
Immunofluorescence (IF) 2 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies

General

Antigen Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies
Epitope Internal Region
(41), (16), (13), (13), (13), (11), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(98), (59), (39), (1), (1), (1), (1), (1)
Host Goat
(92), (14), (12), (2)
Clonality
Polyclonal
Conjugate This LRP5 antibody is un-conjugated
(8), (8), (7), (5), (5), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(76), (59), (32), (23), (13), (6), (3), (3), (2), (2), (2)
Pubmed 1 reference available
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Product Details anti-LRP5 Antibody

Target Details LRP5 Application Details Handling References for anti-LRP5 Antibody (ABIN374570) Images
Specificity This antibody recognizes LRP5.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen Peptide with sequence C-ERVEKTTGDKRT, from the internal region of the protein sequence Genename: LRP5

Target Details LRP5

Product Details anti-LRP5 Antibody Application Details Handling References for anti-LRP5 Antibody (ABIN374570) Images back to top
Antigen
Alternative Name LRP5 (LRP5 Antibody Abstract)
Background LRP5 is involved in the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. Defects in LRP5 are a cause of autosomal dominant and autosomal recessive familial exudative vitreoretinopathy (FEVR). Autosomal dominant FEVR is also referred to as exudative vitreoretinopathy 1 (EVR1), also known as Criswick-Schepens syndrome. FEVR is a disorder of the retinal vasculature characterized by an abrupt cessation of growth of peripheral capillaries, leading to an avascular peripheral retina. This may lead to compensatory retinal neovascularization, which is thought to be induced by hypoxia from the initial avascular insult. New vessels are prone to leakage and rupture causing exudates and bleeding, followed by scarring, retinal detachment and blindness. FEVR is reported to have a penetrance of 100 % , but clinical features can be highly variable, even within the same family. Patients with mild forms of the disease are asymptomatic, and their only disease-related abnormality is an arc of avascular retina in the extreme temporal periphery.Synonyms: LRP-5, LRP7, Low-density lipoprotein receptor-related protein 5
Gene ID 4041, 9606
UniProt O75197
Research Area Stem Cells, Wnt, Extracellular Matrix, Wnt Signaling
Pathways WNT Signaling

Application Details

Product Details anti-LRP5 Antibody Target Details LRP5 Handling References for anti-LRP5 Antibody (ABIN374570) Images back to top
Application Notes Peptide ELISA: Detection Limit: 1/128000. Immunohistochemistry: 3-6 μg/mL. In Paraffin Embedded Human Kidney shows primarily nuclear envelope staining in PCT-.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-LRP5 Antibody Target Details LRP5 Application Details References for anti-LRP5 Antibody (ABIN374570) Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-LRP5 Antibody (ABIN374570)

Product Details anti-LRP5 Antibody Target Details LRP5 Application Details Handling Images back to top
Background publications

He, Semenov, Tamai, Zeng: "LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way." in: Development (Cambridge, England), Vol. 131, Issue 8, pp. 1663-77, 2004

Images

Product Details anti-LRP5 Antibody Target Details LRP5 Application Details Handling References for anti-LRP5 Antibody (ABIN374570) back to top
Supplier Images
 image for anti-LRP5 antibody (Low Density Lipoprotein Receptor-Related Protein 5) (Internal Region) (ABIN374570) anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (Internal Region) antibody