anti-Rat (Rattus) LRP5 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended LRP5 Antibody (supplied by: Log in to see )

Antigen
Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies
  • Xlrp5
  • bmnd1
  • evr1
  • evr4
  • hbm
  • lr3
  • lrp5-A
  • lrp7
  • oppg
  • ops
  • opta1
  • vbch2
  • LRP5
  • LRP6
  • BMND1
  • EVR1
  • EVR4
  • HBM
  • LR3
  • LRP7
  • OPPG
  • OPS
  • OPTA1
  • VBCH2
  • mKIAA4142
  • low density lipoprotein receptor-related protein 5
  • LRP5
  • lrp5
  • LOC100220027
  • Lrp5
Epitope
AA 500-550
33
15
15
14
11
9
9
5
5
5
3
3
2
2
2
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
105
81
48
3
2
1
1
1
1
Host
Rabbit
97
16
12
2
Clonality
Polyclonal
Conjugate
This LRP5 antibody is un-conjugated
8
8
7
5
5
5
3
3
3
2
2
2
2
2
2
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
81
61
36
28
13
7
5
4
2
2
2
1
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Catalog No. ABIN754078
$ 295.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN801618 IF (p) IHC (p) WB Rabbit IgG AA 1470-1520, pThr1492 Log in to see Polyclonal
1 ABIN5553094 EIA IHC (p) Goat Internal Region Log in to see Polyclonal
1 ABIN754087 IHC (p) WB HRP Rabbit IgG AA 500-550 Log in to see Polyclonal
1 ABIN801627 IHC (p) WB HRP Rabbit IgG AA 1470-1520, pThr1492 Log in to see Polyclonal
1 ABIN754080 IHC (p) WB Biotin Rabbit IgG AA 500-550 Log in to see Polyclonal
1 ABIN801620 IHC (p) WB Biotin Rabbit IgG AA 1470-1520, pThr1492 Log in to see Polyclonal
1 ABIN1804577 IHC (p) WB Rabbit Log in to see Polyclonal

General

Antigen Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies
Epitope AA 500-550
(33), (15), (15), (14), (11), (9), (9), (5), (5), (5), (3), (3), (2), (2), (2), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(105), (81), (48), (3), (2), (1), (1), (1), (1)
Host Rabbit
(97), (16), (12), (2)
Clonality
Polyclonal
Conjugate This LRP5 antibody is un-conjugated
(8), (8), (7), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(81), (61), (36), (28), (13), (7), (5), (4), (2), (2), (2), (1)
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Product Details anti-LRP5 Antibody

Target Details LRP5 Application Details Handling Images
Specificity This antibody will recognize LRP6 due to high sequence similarity.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human LRP5
Isotype IgG

Target Details LRP5

Product Details anti-LRP5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name LRP5 (LRP5 Antibody Abstract)
Background

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Appears be required for postnatal control of vascular regression in the eye. Required for posterior patterning of the epiblast during gastrulation.

Subcellular location: Extracellular

Synonyms: HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, LRP-5, OPTA1, VBCH2, Low-density lipoprotein receptor-related protein 5, LRP5

Gene ID 4041
UniProt O75197
Research Area Stem Cells, Wnt, Extracellular Matrix
Pathways WNT Signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-LRP5 Antibody Target Details LRP5 Handling Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-LRP5 Antibody Target Details LRP5 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-LRP5 Antibody Target Details LRP5 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) (AA 500-550) antibody (ABIN754078) Formalin-fixed and paraffin embedded mouse colon carcinoma labeled with Rabbit Anti L...