anti-Rat (Rattus) LRP5 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended LRP5 Antibody (supplied by: Log in to see )

Antigen
Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies
  • Xlrp5
  • bmnd1
  • evr1
  • evr4
  • hbm
  • lr3
  • lrp5-A
  • lrp7
  • oppg
  • ops
  • opta1
  • vbch2
  • LRP5
  • LRP6
  • BMND1
  • EVR1
  • EVR4
  • HBM
  • LR3
  • LRP7
  • OPPG
  • OPS
  • OPTA1
  • VBCH2
  • mKIAA4142
  • low density lipoprotein receptor-related protein 5
  • LRP5
  • lrp5
  • LOC100220027
  • Lrp5
Epitope
Internal Region
33
15
15
15
10
9
9
5
5
5
3
3
2
2
2
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
105
81
48
3
2
1
1
1
1
Host
Goat
98
15
12
2
Clonality
Polyclonal
Conjugate
This LRP5 antibody is un-conjugated
8
8
7
5
5
5
3
3
3
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
82
61
36
29
13
7
5
3
2
2
2
1
Supplier
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Catalog No. ABIN5553094
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN754078 IF (p) IHC (p) WB Rabbit IgG AA 500-550 Log in to see Polyclonal
1 ABIN801618 IF (p) IHC (p) WB Rabbit IgG AA 1470-1520, pThr1492 Log in to see Polyclonal
1 ABIN754087 IHC (p) WB HRP Rabbit IgG AA 500-550 Log in to see Polyclonal
1 ABIN801627 IHC (p) WB HRP Rabbit IgG AA 1470-1520, pThr1492 Log in to see Polyclonal
1 ABIN754080 IHC (p) WB Biotin Rabbit IgG AA 500-550 Log in to see Polyclonal
1 ABIN801620 IHC (p) WB Biotin Rabbit IgG AA 1470-1520, pThr1492 Log in to see Polyclonal
1 ABIN1804577 IHC (p) WB Rabbit Log in to see Polyclonal

Similar anti-LRP5 Antibodies

Application / Reactivity Human Rat (Rattus) Mouse (Murine)
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 1 Antibodies
Cytometry by Time of Flight (CyTOF) 1 Antibodies
Western Blotting (WB) 61 Antibodies 48 Antibodies 16 Antibodies
Immunoprecipitation (IP) 2 Antibodies 4 Antibodies 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies 12 Antibodies 8 Antibodies
Immunohistochemistry (IHC) 33 Antibodies 13 Antibodies 6 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 29 Antibodies 29 Antibodies 29 Antibodies

General

Antigen Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibodies
Epitope Internal Region
(33), (15), (15), (15), (10), (9), (9), (5), (5), (5), (3), (3), (2), (2), (2), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(105), (81), (48), (3), (2), (1), (1), (1), (1)
Host Goat
(98), (15), (12), (2)
Clonality
Polyclonal
Conjugate This LRP5 antibody is un-conjugated
(8), (8), (7), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(82), (61), (36), (29), (13), (7), (5), (3), (2), (2), (2), (1)
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Product Details anti-LRP5 Antibody

Target Details LRP5 Application Details Handling Images
Specificity This antibody recognizes LRP5.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen Peptide with sequence C-ERVEKTTGDKRT, from the internal region of the protein sequence Genename: LRP5

Target Details LRP5

Product Details anti-LRP5 Antibody Application Details Handling Images back to top
Antigen
Alternative Name LRP5 (LRP5 Antibody Abstract)
Background LRP5 is involved in the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. Defects in LRP5 are a cause of autosomal dominant and autosomal recessive familial exudative vitreoretinopathy (FEVR). Autosomal dominant FEVR is also referred to as exudative vitreoretinopathy 1 (EVR1), also known as Criswick-Schepens syndrome. FEVR is a disorder of the retinal vasculature characterized by an abrupt cessation of growth of peripheral capillaries, leading to an avascular peripheral retina. This may lead to compensatory retinal neovascularization, which is thought to be induced by hypoxia from the initial avascular insult. New vessels are prone to leakage and rupture causing exudates and bleeding, followed by scarring, retinal detachment and blindness. FEVR is reported to have a penetrance of 100 % , but clinical features can be highly variable, even within the same family. Patients with mild forms of the disease are asymptomatic, and their only disease-related abnormality is an arc of avascular retina in the extreme temporal periphery.Synonyms: LRP-5, LRP7, Low-density lipoprotein receptor-related protein 5
Gene ID 4041, 9606
UniProt O75197
Research Area Extracellular Matrix, Stem Cells, Wnt, Wnt Signaling
Pathways WNT Signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-LRP5 Antibody Target Details LRP5 Handling Images back to top
Application Notes Peptide ELISA: Detection Limit: 1/128000. Immunohistochemistry: 3-6 μg/mL. In Paraffin Embedded Human Kidney shows primarily nuclear envelope staining in PCT-.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-LRP5 Antibody Target Details LRP5 Application Details Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.