anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antibodies

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters.

list all antibodies Gene Name GeneID UniProt
Anti-Human ABCB1 ABCB1 5243 P08183
Anti-Rat ABCB1 ABCB1 170913  
Anti-Mouse ABCB1 ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 287 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Log in to see 4 to 6 Days
$280.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-ABCB1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC Immunohistochemistry: MDR1/ABCB1 Antibody (1A7) [NBP2-46466] - Analysis of Adenocarcinoma of Human breast tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min) Immunohistochemistry: MDR1/ABCB1 Antibody (1A7) [NBP2-46466] - Analysis of Carcinoma of Human pancreas tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. Western blot using  affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. Personal Communication, Anna Calcagno, CCR-NCI, Bethesda, MD. 100 μg Log in to see 1 to 2 Days
$389.00
Details
Human Mouse Un-conjugated ICC, IHC (fro), IHC (p), WB   100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Mouse Un-conjugated IHC, IHC (p) 100 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: MDR1/ABCB1 Antibody [NBP1-90291] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. Immunohistochemistry-Paraffin: MDR1/ABCB1 Antibody  - Staining of human liver shows cytoplasmic positivity in hepatocytes. 0.1 mL Log in to see 10 to 13 Days
$491.63
Details
Dog Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 8 to 11 Days
$619.30
Details
Hamster Rabbit Un-conjugated IHC, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$727.83
Details

Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies

  1. Human Polyclonal ABCB1 Primary Antibody for IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. in Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724927 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724923 : Rubi?, Ho?ysz, Barczak, Gryczka, ?aci?ski, Jagielski, Czernikiewicz, Pó?rolniczak, Wojewoda, Perz, Bia?ek, Morze, Kandu?a, Lisiak, Mrozikiewicz, Grodecka-Gazdecka, Rybczy?ska: Study of ABCB1 polymorphism frequency in breast cancer patients from Poland. in Pharmacological reports : PR 2013 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal ABCB1 Primary Antibody for IHC (fro), FACS - ABIN2479419 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN2479422 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN2479424 : Koziolek, Riess, Geiger, Thévenod, Hauser: Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. in Kidney international 2001 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN2479421 : Park, Lomri, Simeoni, Fruehauf, Mechetner: Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003 (PubMed)
    Show all 4 Pubmed References

  8. Human Polyclonal ABCB1 Primary Antibody for IHC (fro), IHC (p) - ABIN3043967 : Gao, Liu, Wang, Lin, Zhang: Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells. in Medical oncology (Northwood, London, England) 2010 (PubMed)
    Show all 2 Pubmed References

  9. Human Monoclonal ABCB1 Primary Antibody for ICC, IHC (fro) - ABIN3043101 : Wang, Deng, Lu, Xu, Yan, Ye, Chen et al.: Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 ... in Basic & clinical pharmacology & toxicology 2012 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal ABCB1 Primary Antibody for ELISA, WB - ABIN129711 : Al-Shawi, Omote: The remarkable transport mechanism of P-glycoprotein: a multidrug transporter. in Journal of bioenergetics and biomembranes 2006 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Interaction Partners

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. these findings indicated that CH reversed Pglycoprotein-mediated MDR in Ovarian cancer A2780/Taxol cells by inhibiting the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway.

  2. ABCB1 hypomethylation is associated with lower drug absorption, higher platelet reactivity, and an increased risk of ischemic events in our patients.

  3. MDR1 (show TBC1D9 Antibodies) gene variants and haplotypes were associated with ulcerative colitis in Serbian patients.

  4. The novel role of HCAR1 (show GPR81 Antibodies) in development of chemoresistance in cervical carcinoma HeLa cells via ABCB1 transporter up-regulation.

  5. ABCB1 genotype rs1045642 AA is associated with fentanyl administration in a cohort of children admitted to the pediatric intensive care unit, likely because of decreased expression and activity of p-glycoprotein

  6. These results suggested that ABCB1 rs1045642 and UGT2B7 rs7439366 may affect oxcarbazepine pharmacokinetics and therapeutic efficacy in Han Chinese patients with epilepsy

  7. results suggest that the ABCB1 3435C > T SNP, the 2677G > T/A SNP and 1236T/2677T/3435C haplotype are significantly associated with AD susceptibility

  8. MDR1 (show TBC1D9 Antibodies) polymorphisms could affect the prognosis of multiple myeloma.

  9. The MDR1 (show TBC1D9 Antibodies)/CYP3A4 (show CYP3A4 Antibodies)/OPRM1 (show OPRM1 Antibodies) gene polymorphisms influenced the fentanyl consumption and the physiological effects of intravenous analgesia in the Chinese women who received lower segment caesarean section surgeries.

  10. Compared with palonosetron, ramosetron may be superior for reducing PONV severity, especially in patients with ABCB1 3435TT or 2677TT genotype

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (show ABCB4 Antibodies), Bcrp and Mrp1 (show ABCC1 Antibodies) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Data suggest that the overexpression of P-gp (show ABCB4 Antibodies) in neoplastic cells may be associated with alterations in O-glycosylated cell surface proteins, including mucins, and this alteration may be responsible for the reduced cell sensitivity to the O-glycosylation inhibitor GalNAc-alpha-O-benzyl.

  2. We conclude that mdr1b and bcrp are essential to ovarian protection from chemotoxicity and may have an important physiological role in the ovary.

  3. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp (show ABCB4 Antibodies), multi-drug resistance protein, MDR1 (show ABCB4 Antibodies)).Drugs with ER < 1 (show MIER1 Antibodies) almost do not bind the main binding cavity (MBC (show CACNA1C Antibodies)) of P-gp (show ABCB4 Antibodies).

  4. conclusion, MDR1 (show ABCB4 Antibodies) and BCRP are expressed on apical membranes of the rodent placental SynT (show STX1A Antibodies)-II layer.

  5. Mdr1 (show ABCB4 Antibodies) enforces T Cell homeostasis in the presence of intestinal bile acids.

  6. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  7. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (show ABCB4 Antibodies) ATPase (show DNAH8 Antibodies) activity

  8. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  9. Chrysosplenetin inhibited P-gp (show ABCB4 Antibodies) activity and reverse the up-regulated P-gp (show ABCB4 Antibodies) and MDR1 (show ABCB4 Antibodies) levels induced by artemisinin.

  10. Tamsulosin and tolterodine with P-gp (show ABCB4 Antibodies) gene expression and activity in an enantiomer-specific way.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP binding cassette subfamily B member 1 (ABCB1) antibody
  • ATP binding cassette subfamily B member 1A (Abcb1a) antibody
  • ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP binding cassette subfamily B member 1 (Abcb1) antibody
  • ABC20 antibody
  • ABCB1 antibody
  • CD243 antibody
  • CLCS antibody
  • GP170 antibody
  • mdr antibody
  • Mdr1 antibody
  • Mdr1a antibody
  • Mdr1b antibody
  • p-gp antibody
  • PGP1 antibody
  • Pgy-1 antibody
  • Pgy1 antibody
  • xemdr antibody

Protein level used designations for ABCB1

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , bovine P-glycoprotein , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B

GENE ID SPECIES
5243 Homo sapiens
170913 Rattus norvegicus
281585 Bos taurus
403879 Canis lupus familiaris
397812 Xenopus laevis
463516 Pan troglodytes
18669 Mus musculus
100682536 Cricetulus griseus
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