anti-Acetyl-CoA Acetyltransferase 2 (ACAT2) Antibodies

The product of ACAT2 is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. Additionally we are shipping ACAT2 Kits (30) and ACAT2 Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACAT2 39 Q9BWD1
ACAT2 110460 Q8CAY6
ACAT2 308100 Q5XI22
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Top anti-ACAT2 Antibodies at antibodies-online.com

Showing 10 out of 109 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-ACAT2 Antibody Titration: </b>1.0ug/ml<br><b>Positive Control: </b>K562 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-ACAT2 Antibody Titration: </b>2.0ug/ml<br><b>Positive Control: </b>K562 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$245.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: ACAT2 Antibody [NBP1-89525] - Staining of human testis shows strong cytoplasmic positivity in leydig cells. Immunocytochemistry/ Immunofluorescence: ACAT2 Antibody [NBP1-89525] - Staining of human cell line A-431 shows positivity in cytoplasm & mitochondria. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: ACAT2 Antibody [NBP1-89526] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: ACAT2 Antibody [NBP1-89526] - Immunohistochemical staining of human testis shows strong cytoplasmic positivity in leydig cells. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Bat Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Cow Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-ACAT2 mouse monoclonal antibody (ABIN2453825) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACAT2 (RC201821). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACAT2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ACAT2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Dog Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$493.17
Details

ACAT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)


Rat (Rattus)
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Top referenced anti-ACAT2 Antibodies

  1. Human Polyclonal ACAT2 Primary Antibody for IHC, IHC (p) - ABIN4277554 : Go, Srivastava, Hernandez-Ono, Gang, Smith, Booth, Ginsberg, Mani: The combined hyperlipidemia caused by impaired Wnt-LRP6 signaling is reversed by Wnt3a rescue. in Cell metabolism 2014 (PubMed)

  2. Human Polyclonal ACAT2 Primary Antibody for ICC, IF - ABIN4277555 : Martinez-Outschoorn, Lin, Whitaker-Menezes, Howell, Sotgia, Lisanti: Ketone body utilization drives tumor growth and metastasis. in Cell cycle (Georgetown, Tex.) 2012 (PubMed)

More Antibodies against ACAT2 Interaction Partners

Human Acetyl-CoA Acetyltransferase 2 (ACAT2) interaction partners

  1. Lipid-induced stabilization of ACAT2 ameliorates lipotoxicity from excessive cholesterol and fatty acid. Cysteine ubiquitylation of ACAT2 constitutes an important mechanism for sensing lipid-overload-induced ROS and fine-tuning lip (show ROS1 Antibodies)id homeostasis.

  2. data demonstrate that the ACAT2 expression of human leukocytes is responsible for the excretion of lipoproteins containing cholesteryl/steryl esters (CE/SE), and suggest that the excretion of lipoproteins containing the ACAT2-catalyzed CS/SE may avoid cytotoxicity

  3. results demonstrate that the low-level expression of human ACAT2 gene with specific CpG-hypomethylated promoter is regulated by the C/EBP transcription factors in monocytic cells, and imply that the lowly expressed ACAT2 catalyzes the synthesis of certain CE/SE that are assembled into lipoproteins for the secretion

  4. Low ACAT2 expression is associated with clear cell renal cell carcinoma (show MOK Antibodies).

  5. results show that the enzymatic activity of mutant Glu(14)Gly is approximately two times higher than wildtype, and that this increase is primarily due to the increased expression and/or stability of the mutant ACAT2 protein

  6. Results show that DLAT (show DLAT Antibodies) and ACAT2 as upstream acetyltransferases of K76 and K294 in 6PGD (show PGD Antibodies) protein.

  7. Reduced ACAT2 is associated with impaired butyrate oxidation in ulcerative colitis.

  8. HNF4alpha positively regulates ACAT2 gene expression at mRNA level. Overexpression of HNF4alpha increased ACAT2 expression, whereas knockdown of HNF4alpha decreased ACAT2 expression.

  9. Describe a gender-related difference in hepatic ACAT2 activity in normolipidemic non-obese Chinese patients suggesting a possible role for ACAT2 in the regulation of cholesterol metabolism in humans.

  10. Data describe the high resolution structure of human cytosolic acetoacetyl-CoA thiolase (CT), both unliganded (at 2.3 angstroms resolution) and in complex with CoA (at 1.6 angstroms resolution).

Mouse (Murine) Acetyl-CoA Acetyltransferase 2 (ACAT2) interaction partners

  1. lipid-induced stabilization of ACAT2 (show SOAT2 Antibodies) ameliorates lipotoxicity from excessive cholesterol and fatty acid. This unconventional cysteine ubiquitylation of ACAT2 (show SOAT2 Antibodies) constitutes an important mechanism for sensing lipid-overload-induced ROS (show ROS1 Antibodies) and fine-tuning lipid homeostasis.

  2. Intestine-specific MTP (show LAPTM4A Antibodies) and global ACAT2 (show SOAT2 Antibodies) deficiency lowers acute cholesterol absorption with chylomicrons and HDLs (show CSF1R Antibodies)

  3. ACAT2 (show SOAT2 Antibodies) seems to be a hepatic player affecting the cholesterol fluxes fated to VLDL or to HDL (show HSD11B1 Antibodies), the latter via up-regulation of ABCA1 (show ABCA1 Antibodies)

  4. handling of sterols by the intestine involves both G5G8 and ACAT2 but that an additional factor (possibly Niemann-Pick C1-like 1) may be key in determining absorption efficiency

  5. inhibition of intestinal or hepatic ACAT2 improves atherogenic hyperlipidemia and limits hepatic cholesteryl ester accumulation

  6. Pyripyropene ACAT2-selective inhibition in the intestine and the liver can be effective against atherosclerosis.

  7. Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (show SOAT2 Antibodies) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization.

  8. ACAT2 (show SOAT2 Antibodies) provides core CE of newly secreted VLDL, whereas LCAT (show LCAT Antibodies) adds CE during LDL particle formation

  9. ABCA1 (show ABCA1 Antibodies), especially in the absence of ACAT2 (show SOAT2 Antibodies), can have a significant effect on cholesterol absorption, although ACAT2 (show SOAT2 Antibodies) has a more substantial role in this process than ABCA1 (show ABCA1 Antibodies)

  10. depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss

Arabidopsis thaliana Acetyl-CoA Acetyltransferase 2 (ACAT2) interaction partners

  1. The AACT2-derived acetoacetyl CoA pool generates isoprenoids that are required for normal growth and development. AACT2 is essential and cannot be replaced by AACT1. AACT1 and AACT2 exhibit differential spatial and temporal expression patterns.

Pig (Porcine) Acetyl-CoA Acetyltransferase 2 (ACAT2) interaction partners

  1. ACAT2 might contribute more to metabolic processes than ACAA2 (show ACAA2 Antibodies) in swine.

ACAT2 Antigen Profile

Protein Summary

The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.

Gene names and symbols associated with ACAT2

  • acetyl-CoA acetyltransferase 2 (ACAT2) antibody
  • acetyl-Coenzyme A acyltransferase 2 (CNA05060) antibody
  • acetyl-CoA acetyltransferase 2 (acat2) antibody
  • acetyl-Coenzyme A acetyltransferase 2 (Acat2) antibody
  • acetyl-CoA acetyltransferase 2 (Acat2) antibody
  • acetyl-CoA acetyltransferase 2 S homeolog (acat2.S) antibody
  • acetoacetyl-CoA thiolase 2 (ACAT2) antibody
  • Ab2-076 antibody
  • Acat3 antibody
  • acetoacetyl-CoA thiolase 2 antibody
  • AW742799 antibody
  • EMB1276 antibody
  • EMBRYO DEFECTIVE 1276 antibody
  • fb10a06 antibody
  • fb53f08 antibody
  • MIF21.12 antibody
  • MIF21_12 antibody
  • Tcp-1x antibody
  • Tcp1-rs1 antibody
  • wu:fb10a06 antibody
  • wu:fb53f08 antibody

Protein level used designations for ACAT2

acetoacetyl Coenzyme A thiolase , acetyl-CoA acetyltransferase, cytosolic , acetyl-CoA transferase-like protein , cytosolic acetoacetyl-CoA thiolase , acetyl-Coenzyme A acyltransferase 2 , etID39354.20 , t-complex protein 1, related sequence 1 , acetyl-Coenzyme A acetyltransferase 2 , acetyl-Coenzyme A acetyltransferase 3 , acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) , acetyl-CoA acetyltransferase 2 , acetyl-CoA acetyltransferase, cytosolic-like

GENE ID SPECIES
39 Homo sapiens
3253349 Cryptococcus neoformans var. neoformans JEC21
30643 Danio rerio
110460 Mus musculus
308100 Rattus norvegicus
394562 Xenopus (Silurana) tropicalis
398120 Xenopus laevis
421587 Gallus gallus
484063 Canis lupus familiaris
497249 Monodelphis domestica
512044 Bos taurus
834876 Arabidopsis thaliana
100172365 Pongo abelii
100410799 Callithrix jacchus
100477493 Ailuropoda melanoleuca
100152303 Sus scrofa
100714379 Cavia porcellus
101111975 Ovis aries musimon
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