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Molecular chaperone\; assists the folding of proteins upon ATP hydrolysis. Additionally we are shipping Chaperonin Containing TCP1, Subunit 8 (Theta) Antibodies (80) and Chaperonin Containing TCP1, Subunit 8 (Theta) Kits (3) and many more products for this protein.
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Study demonstrated that CCT8 expression is widely upregulated in esophageal squamous cell carcinoma (ESCC), and enhanced the migration and invasion of ESCC cells, indicating that ectopic CCT8 expression contributes to the highly aggressive nature of ESCC probably by increasing alpha-actin and beta-tubulin expression.
Ectopic expression of CCT8 also ameliorates the age-associated demise of proteostasis and corrects proteostatic deficiencies in worm models of Huntington's disease.
data suggest that the GRP94/CCT8/c-Jun/EMT signaling cascade might be a new therapeutic target for HCC
showed that high CCT8 protein expression might be related to poor outcome of glioma
CCT8 mRna levels are associated with male fertility.
transcription of the Cctq gene is regulated by TCFs under the control of the Ras/MAPK pathway, probably independently of serum response factor.
Molecular chaperone\; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
chaperonin containing TCP1, subunit 8 (theta)
, T-complex protein 1 subunit theta
, T-complex protein 1 subunit theta-like
, T-complex protein 1, theta subunit
, renal carcinoma antigen NY-REN-15
, chaperonin subunit 8 (theta)
, bette davis
, chaperonin subunit 8 theta