Chemokine (C-C Motif) Ligand 20 Proteins (CCL20)

chemokine upregulated in ischemic brain tissue [RGD, Feb 2006].. Additionally we are shipping CCL20 Antibodies (180) and CCL20 Kits (112) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCL20 6364 P78556
CCL20 20297 O89093
CCL20 29538 P97884
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Top CCL20 Proteins at

Showing 10 out of 74 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
Escherichia coli (E. coli) Mouse Un-conjugated 100 μg 1 to 2 Days
Escherichia coli (E. coli) Human Un-conjugated 100 μg 1 to 2 Days
Escherichia coli (E. coli) Human Un-conjugated Validation with Western Blot 20 μg 4 to 8 Days
Escherichia coli (E. coli) Mouse His tag 100 μg 15 to 18 Days
Escherichia coli (E. coli) Rat His tag,GST tag 100 μg 15 to 18 Days
Escherichia coli (E. coli) Mouse Un-conjugated Validation with Western Blot 20 μg 4 to 8 Days
Escherichia coli (E. coli) Human GST tag Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 27-95), (full length) protein (GST tag) 1 mg 60 to 71 Days
Escherichia coli (E. coli) Rat Un-conjugated Validation with Western Blot 10 μg 4 to 8 Days

CCL20 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) , ,
Rat (Rattus) ,

Top referenced CCL20 Proteins

  1. Human CCL20 Protein expressed in - ABIN621130 : Galli, Basilico, Cortese, Di Giusto: [Spontaneous hematoma of the abdominal wall. Review of a clinical case load]. in Minerva chirurgica 1990 (PubMed)
    Show all 2 Pubmed References

More Proteins for Chemokine (C-C Motif) Ligand 20 (CCL20) Interaction Partners

Pig (Porcine) Chemokine (C-C Motif) Ligand 20 (CCL20) interaction partners

  1. results suggest that CCL20 may improve the endometrial receptivity through inducing proliferative signal transduction in the porcine endometrium during the early gestational period

Rhesus Monkey Chemokine (C-C Motif) Ligand 20 (CCL20) interaction partners

  1. Hypoxia is a transcriptional inducer of CCL20 in human mononuclear phagocytes.

Human Chemokine (C-C Motif) Ligand 20 (CCL20) interaction partners

  1. The serum CCL20 level was significantly elevated in patients with vitiligo. The level of serum CCL20 was higher in active than in the stable stage. Patients with active vitiligo had elevated numbers of circulating Th1/17 cells and Tc1/17 cells, and upregulated expression of CCR6 in PBMCs and lesions.

  2. CCL20 enhanced doxorubicin resistance of OC cells by regulating ABCB1 expression

  3. High CCL20 level is associated with Abdominal Aortic Aneurysm.

  4. expression of CCL20, an important inflammatory mediator, is increased in Nonalcoholic fatty liver disease fibrosis.

  5. Elevated CCL20 production by airway smooth muscle cells, possibly resulting from dysregulated expression of the anti-inflammatory miR-146a-5p, may contribute to enhanced mucus production in asthma.

  6. We postulate CCL20 does not activate CCR6 through the canonical two-step/two-site mechanism of chemokine-chemokine receptor activation

  7. CCL20 can be a novel predictive marker for taxane response, and the blockade of CCL20 or its downstream pathway might reverse the taxane resistance in breast cancer patients.

  8. CCL20, which is regulated by HuR and secreted into the bone microenvironment, enhances the metastatic ability and bone metastasis of breast cancer cells by stimulating cancer cells and osteoblastic cells in both autocrine and paracrine manners.

  9. CCl20 and CXCL13 synergistically increased B-cell migration form peripheral blood of rheumatoid arthritis patients.

  10. CCL20 role in glioblastoma.CCL20 expression in astrocytes during hypoxia.CCL20 up-regulates HIF-1alpha through NF-kappaB activation.

  11. S1P induced the expression of some asthma-related genes, such as ADRB2, PTGER4, and CCL20, in bronchial epithelial cells. The knock-down of SIPR3 suppressed the expression of S1P-inducing CCL20.

  12. CCL20 was upregulated in giant cell tumor of bone patients and correlated with tumor progression and poor prognosis. CCL20 recruited mononuclear cells and induced osteoclastogenesis by over-activating the AKT and NF-kappa B signaling pathways.

  13. CCL20 may play an important role in the pathogenesis of MS. Both allelic variation of (rs6749704) within CCL20 gene and (rs763780) within IL-17F gene can be considered risk factor for development of MS in Egyptian patients.

  14. These results provide evidence that necrotic cells induce the expression of CCL2/MCP-1 and CCL20/MIP-3alpha in glioblastoma cells through activation of NF-kappaB and AP-1 and facilitate the infiltration of microglia into tumor tissues.

  15. CCN1 stimulates CCL20 production in vitro and in vivo, and thus supports the notion that overexpressed CCN1 in hyperproliferating keratinocyte is functionally involved in the recruitment of inflammatory cells to skin lesions affected by psoriasis.

  16. Results demonstrated that F. nucleatum ssp. animalis and dysregulated CCL20 protein expression are important factors associated with human colorectal cancer progression.

  17. There was underexpression of the majority of genes after sunitinib treatment. The lower expression levels of IGFBP1, CCL20, CXCL6 and FGB were confirmed by qRT-PCR in all cases. The downregulation of gene expression leads us to search for methylation as a mechanism of action of the tyrosine kinase inhibitors

  18. CCL20 contributed to invasion and epithelial-mesenchymal transition of RANK over-expressed endometrial cancer cells

  19. High expression of CCL20 is associated with cutaneous T-cell lymphoma.

  20. These results showed that the higher levels of CXCL10, CCL20 and CCL22 were associated with ischemic heart disease. The serum levels of chemokines may influence by the certain traditional risk factors of IHD and some studied SNPs, but did not influence by treatment and gender of patients.

Mouse (Murine) Chemokine (C-C Motif) Ligand 20 (CCL20) interaction partners

  1. Study provides evidence that CCL20 expression and its mRNA level are regulated by TDAG8.

  2. Obesity-induced IL-6 shifts macrophage polarization towards tumor-promoting macrophages that produce the CCL-20 in the colitis-associated colorectal cancer (CAC) microenvironment. CCL-20 promotes CAC progression by recruiting CCR6-expressing B-cells and gammadelta T cells via chemotaxis.

  3. Blocking or knockdown CCN1 expression ameliorated skin inflammation and reduced the expression of CCL20 in both imiquimod and IL-23-induced psoriasis-like mouse models.

  4. these data indicate that CCL20/CCR6 signaling may play an important role in regulating bone mass accrual, potentially by modulating osteoblast maturation, survival, and the recruitment of osteoblast-supporting cells.

  5. We crossed Ptf1a(Cre/+) ;Kras(G12D/+) mice with JNK1(-/-) mice to generate Ptf1a(Cre/+) ;Kras(G12D/+) ;JNK1(-/-) (Kras;JNK1(-/-) ) mice. Tumor weight was significantly lower in Kras;JNK1(-/-) mice than in Kras;JNK1(+/-) mice, whereas histopathological features were similar.we concluded that inhibition of activated JNK in pancreatic tumor stroma could be a potential therapeutic target to increase Ccl20 secretion

  6. mutually exclusive transcriptional regulation by AP-1 (cjun/cfos) and non-canonical NF-kappaB (RelB/p52) downstream of MEK-ERK and NIK-IKK-alpha-NF-kappaB2 (p100) phosphorylation, respectively was responsible for persistent Ccl20 expression in the colonic cells.

  7. Taken together, these data show that, in adipose tissues, IL-17A contributes to exacerbating insulin resistance-enhancing IL-6 production and promotes the infiltration of Th17 cells in cooperation with TNFalpha; these findings represent a novel hypothesis for the association between IL-17A-producing cells and type 2 diabetes.

  8. Data (including data from studies in knockout/mutant mice) suggest that expression of Ahr (aryl-hydrocarbon receptor) and its translocation into nucleus are necessary for Ahr ligand-mediated synergistic induction of Ccl20; here, TCDD is Ahr ligand.

  9. alpha-hemolytic streptococcus may exacerbate kidney damage in IgA nephropathy through CCL20 response to the effect of Th17 cells.

  10. Acquired mtDNA mutations may promote tumorigenic phenotypes through up-regulation of chemokine CCL20.

  11. Overexpression of CCL20 in human proximal tubular cells is inhibited by blockade of KCa3.1 under diabetic conditions through inhibition of the NF-kappaB pathway.

  12. Our data indicate that estradiol is important in regulating the effects of keratinocyte growth factor on mouse uterine epithelial cell secretion of CCL20 and CXCL1.

  13. CCL20 blockage lead to a diminished cerebral immune response in experimental pneumococcal meningitis.

  14. This study suggests that CCL20/IL-15 can induce a strong antitumor immune response in tumor tissues and it is a suitable candidate for cancer immunotherapy.

  15. Estrogen receptors alpha regulates CCL20/CXCL1 secretion in the female reproductive tract.

  16. Cardiac fibroblasts could recruit Th17 cells infiltration into myocardium by secreting CCL20 in acute viral myocarditis.

  17. Data indicate that a CCR6/CCL20 chemokine loop instructed rapid increase of B cells in the spleen in response to systemic administration of Nod1 agonists in a TNF-alpha-dependent manner.

  18. Neutralization of CCL20 before induction of sepsis increased mortality during sepsis accompanied with increasing epithelial apoptosis in the jejunum and augmenting serum TNF-alpha.

  19. CXCR3 promotes recruitment of Th17 cells from the blood into the liver in both human and murine liver injury. Their subsequent positioning near bile ducts is dependent on CCR6 and cholangiocyte-secreted CCL20.

  20. Findings suggest that TNF-alpha is essential in the induction of autoimmune hepatitis (AIH) through upregulation of hepatic CCL20 expression, which allows migration of dysregulated splenic T cells.

CCL20 Protein Profile

Protein Summary

chemokine upregulated in ischemic brain tissue

Gene names and symbols associated with CCL20

  • C-C motif chemokine ligand 20 (CCL20)
  • chemokine (C-C motif) ligand 20b (ccl20b)
  • chemokine (C-C motif) ligand 20 (Ccl20)
  • C-C motif chemokine ligand 20 (Ccl20)
  • CCL20 protein
  • CKb4 protein
  • exodus-1 protein
  • LARC protein
  • MIP-3-alpha protein
  • MIP-3A protein
  • MIP-3ALPHA protein
  • MIP-3[a] protein
  • MIP3A protein
  • Scya20 protein
  • si:dkey-150o13.1 protein
  • ST38 protein

Protein level used designations for CCL20

C-C motif chemokine 20 , maacrophage inflammatory protein 3alpha , CC chemokine ligand 20 , chemokine (C-C motif) ligand 20 , chemokine CCL20/MIP-3ALPHA , chemokine CCL-C24a , CC chemokine LARC , beta chemokine exodus-1 , liver and activation-regulated chemokine , macrophage inflammatory protein 3 alpha , small inducible cytokine subfamily A (Cys-Cys), member 20 , small-inducible cytokine A20 , CC chemokine ST38 , MIP-3-alpha , beta-chemokine exodus-1 , small inducible cytokine subfamily A20

395082 Gallus gallus
448790 Canis lupus familiaris
459991 Pan troglodytes
553951 Sus scrofa
574182 Macaca mulatta
563152 Danio rerio
6364 Homo sapiens
20297 Mus musculus
29538 Rattus norvegicus
281666 Bos taurus
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